Morphological and Functional Principles Governing the Plasticity Reserve in the Cerebellum: The Cortico-Deep Cerebellar Nuclei Loop Model [PDF]
Biology, 2023 Cerebellar reserve compensates for and restores functions lost through cerebellar damage. This is a fundamental property of cerebellar circuitry. Clinical studies suggest (1) the involvement of synaptic plasticity in the cerebellar cortex for functional ...
Hiroshi Mitoma +3 more
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Cerebellar control of fear learning via the cerebellar nuclei–Multiple pathways, multiple mechanisms? [PDF]
Frontiers in Systems Neuroscience, 2023 Fear learning is mediated by a large network of brain structures and the understanding of their roles and interactions is constantly progressing. There is a multitude of anatomical and behavioral evidence on the interconnection of the cerebellar nuclei ...
Julie D. Urrutia Desmaison +5 more
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Synaptic mechanisms for associative learning in the cerebellar nuclei [PDF]
Nature Communications, 2023 Associative learning during delay eyeblink conditioning (EBC) depends on an intact cerebellum. However, the relative contribution of changes in the cerebellar nuclei to learning remains a subject of ongoing debate.
Robin Broersen +5 more
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The Cerebellar Nuclei and Dexterous Limb Movements. [PDF]
Neuroscience, 2020 Dexterous forelimb movements like reaching, grasping, and manipulating objects are fundamental building blocks of the mammalian motor repertoire. These behaviors are essential to everyday activities, and their elaboration underlies incredible accomplishments by human beings in art and sport. Moreover, the susceptibility of these behaviors to damage and
Thanawalla AR, Chen AI, Azim E.
europepmc +6 more sources
Deep Cerebellar Nuclei Segmentation via Semi-Supervised Deep Context-Aware Learning from 7T Diffusion MRI [PDF]
IEEE Access, 2020 Deep cerebellar nuclei are a key structure of the cerebellum that are involved in processing motor and sensory information. It is thus a crucial step to accurately segment deep cerebellar nuclei for the understanding of the cerebellum system and its ...
Jinyoung Kim +4 more
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Whole-Cell Properties of Cerebellar Nuclei Neurons In Vivo. [PDF]
PLoS ONE, 2016 Cerebellar nuclei neurons integrate sensorimotor information and form the final output of the cerebellum, projecting to premotor brainstem targets. This implies that, in contrast to specialized neurons and interneurons in cortical regions, neurons within
Cathrin B Canto +2 more
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Differentiating Cerebellar Impact on Thalamic Nuclei [PDF]
Cell Reports, 2018 The cerebellum plays a role in coordination of movements and non-motor functions. Cerebellar nuclei (CN) axons connect to various parts of the thalamo-cortical network, but detailed information on the characteristics of cerebello-thalamic connections is ...
Simona V. Gornati +5 more
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Cerebellar Nuclear Neurons Use Time and Rate Coding to Transmit Purkinje Neuron Pauses. [PDF]
PLoS Computational Biology, 2015 Neurons of the cerebellar nuclei convey the final output of the cerebellum to their targets in various parts of the brain. Within the cerebellum their direct upstream connections originate from inhibitory Purkinje neurons. Purkinje neurons have a complex
Shyam Kumar Sudhakar +2 more
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Cerebellar nuclei neurons display aberrant oscillations during harmaline-induced tremor [PDF]
Heliyon, 2021 Summary: Essential tremor, a common, debilitating motor disorder, is thought to be caused by cerebellar malfunction. It has been shown that rhythmic Purkinje cell firing is both necessary and sufficient to induce body tremor.
Yuval Baumel, Hagar G. Yamin, Dana Cohen
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Cross-talk between dopamine and noradrenaline modulates glutamatergic transmission in the deep cerebellar nuclei [PDF]
Scientific ReportsModulation of synaptic transmission in the deep cerebellar nuclei, a major output region of the cerebellum, is essential for regulating motor and non-motor functions by controlling information flow from the cerebellar cortex.
Fumihito Saitow +2 more
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