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The cerebellar nuclei are involved in several brain functions, including the modulation of motor and cognitive performance. To differentiate their participation in these functions, and to analyze their changes in neurodegenerative and other diseases as ...
Stefanie eTellmann +8 more
doaj +2 more sources
The mysterious microcircuitry of the cerebellar nuclei
Abstract The microcircuitry of cerebellar cortex and, in particular, the physiology of its main element, the Purkinje neuron, has been extensively investigated and described. However, activity in Purkinje neurons, either as single cells or populations, does not directly mediate the cerebellar effects on the motor effector systems.
M. Uusisaari, E. De Schutter
semanticscholar +5 more sources
Differential olivo-cerebellar cortical control of rebound activity in the cerebellar nuclei [PDF]
The output of the cerebellar cortex is controlled by two main inputs, (i.e., the climbing fiber and mossy fiber-parallel fiber pathway) and activations of these inputs elicit characteristic effects in its Purkinje cells: that is, the so-called complex spikes and simple spikes.
F. Hoebeek +3 more
semanticscholar +4 more sources
Diffusion spectrum imaging shows the structural basis of functional cerebellar circuits in the human cerebellum in vivo. [PDF]
The cerebellum is a complex structure that can be affected by several congenital and acquired diseases leading to alteration of its function and neuronal circuits.
Cristina Granziera +6 more
doaj +1 more source
Insults to the developing cerebellum can cause motor, language, and social deficits. Here, we investigate whether developmental insults to different cerebellar neurons constrain the ability to acquire cerebellar-dependent behaviors. We perturb cerebellar
Meike E. van der Heijden +6 more
doaj +1 more source
Understanding cerebellar alterations due to healthy aging provides a reference point against which pathological findings in late-onset disease, for example spinocerebellar ataxia type 6 (SCA6), can be contrasted. In the present study, we investigated the
Dominik Jäschke +16 more
doaj +1 more source
Preserved Glucose Metabolism of Deep Cerebellar Nuclei in a Case of Multiple System Atrophy with Predominant Cerebellar Ataxia: F-18 Fluorodeoxyglucose Positron Emission Tomography Study [PDF]
The cerebellar glucose metabolism of multiple system atrophy with predominant cerebellar ataxia (MSA-C) is known to be decreased but is not defined among areas of cerebellum. We encountered a 54-year-old man who developed dizziness and progressive ataxia
Oh Dae Kwon, Chang-Seok Ki
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Memory consolidation in the cerebellar cortex [PDF]
Several forms of learning, including classical conditioning of the eyeblink, depend upon the cerebellum. In examining mechanisms of eyeblink conditioning in rabbits, reversible inactivations of the control circuitry have begun to dissociate aspects of ...
A Gruart +54 more
core +8 more sources
The underpinnings of cerebellar ataxias
The human cerebellum contains more than 60% of all neurons of the brain. Anatomically, the cerebellum is divided into 10 lobules (I-X). The cerebellar cortex is arranged into three layers: the molecular layer (external), the Purkinje cell layer and the ...
Mario Manto
doaj +1 more source

