Results 31 to 40 of about 86,125 (297)

A novel inhibitory nucleo-cortical circuit controls cerebellar Golgi cell activity

open access: yeseLife, 2015
The cerebellum, a crucial center for motor coordination, is composed of a cortex and several nuclei. The main mode of interaction between these two parts is considered to be formed by the inhibitory control of the nuclei by cortical Purkinje neurons.
Lea Ankri   +7 more
doaj   +1 more source

Possible multiple evolution of indirect telencephalo-cerebellar pathways in teleosts: studies in Carassius auratus and Pantodon buchholzi [PDF]

open access: yes, 1993
Among vertebrates, telencephalo-pontine systems exist only in birds and mammals. However, three nuclei in the diencephalon and mesencephalon of teleost fishes have been indicated — analogous to the pons — to represent relay stations between telencephalon
Meyer, Dietrich L., Wullimann, Mario F.
core   +1 more source

Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum

open access: yesNeural Development, 2011
Background The cerebellum is composed of a diverse array of neuronal subtypes. Here we have used a candidate approach to identify Zac1, a tumor suppressor gene encoding a zinc finger transcription factor, as a new player in the transcriptional network ...
Schuurmans Carol   +6 more
doaj   +1 more source

The cerebellum could solve the motor error problem through error increase prediction [PDF]

open access: yes, 2015
We present a cerebellar architecture with two main characteristics. The first one is that complex spikes respond to increases in sensory errors. The second one is that cerebellar modules associate particular contexts where errors have increased in the ...
O'Reilly, Randall C.   +1 more
core   +2 more sources

The deep cerebellar nuclei to striatum disynaptic connection contributes to skilled forelimb movement

open access: yesCell Reports, 2023
Summary: Cerebellar-thalamo-striatal synaptic communication has been implicated in a wide range of behaviors, including goal-directed actions, and is altered in cerebellar dystonia.
Rubén Contreras-López   +4 more
doaj   +1 more source

Spinocerebellar Ataxia Type 2 [PDF]

open access: yes, 2012
1. Introduction: The autosomal dominant cerebellar ataxias (ADCA) are a clinically, pathologically and genetically heterogeneous group of neurodegenerative disorders caused by degeneration of cerebellum and its afferent and efferent connections.
Auburger, Georg   +3 more
core   +1 more source

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit

open access: yesNature Communications, 2023
Synaptic adhesion molecules (SAMs) shape the structural and functional properties of synapses and thereby control the information processing power of neural circuits.
Alessandra Sclip, Thomas C. Südhof
doaj   +1 more source

The spino-bulbar-cerebellar pathway: organization and neurochemical properties of spinal cells that project to the lateral reticular nucleus in the rat [PDF]

open access: yes, 2015
In addition to classical spinocerebellar pathways, the cerebellum receives information from the spinal cord indirectly via spino-bulbar-cerebellar systems. One of the structures in this pathway is the lateral reticular nucleus (LRt).
Huma, Zilli, Maxwell, David J.
core   +2 more sources

Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction [PDF]

open access: yes, 2018
The brain communicates with the spinal cord through numerous axon tracts that arise from discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination of descending commands.
Blackmore, Murray G.   +4 more
core   +2 more sources

Bilateral lesion of the cerebellar fastigial nucleus: Effects on smooth pursuit acceleration and non-reflexive visually-guided saccades

open access: yesFrontiers in Neurology, 2022
Background“Central dizziness” due to acute bilateral midline cerebellar disease sparing the posterior vermis has specific oculomotor signs. The oculomotor region of the cerebellar fastigial nucleus (FOR) crucially controls the accuracy of horizontal ...
Christoph Helmchen   +8 more
doaj   +1 more source

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