Results 91 to 100 of about 28,628 (268)
Vascular neurocognitive disorders and the vascular risk factors [PDF]
, 2018 Dementias are clinical neurodegenerative diseases characterized by permanent and progressive transformation of cognitive functions such as memory, learning capacity, attention, thinking, language, passing judgments, calculation or orientation.
Albu, Carmen V. +7 more
core +4 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker +2 more
wiley +1 more source
Enlarged perivascular spaces as a marker of underlying arteriopathy in intracerebral haemorrhage: a multicentre MRI cohort study. [PDF]
, 2013 Small vessel disease (mainly hypertensive arteriopathy and cerebral amyloid angiopathy (CAA)) is an important cause of spontaneous intracerebral haemorrhage (ICH), a devastating and still poorly understood stroke type. Enlarged perivascular spaces (EPVS)
Baron, JC +8 more
core +1 more source
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Journal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli +12 more
wiley +1 more source
Comorbid cerebral amyloid angiopathy in dementia and prodromal stages—Prevalence and effects on cognition [PDF]
, 2023 Robert Haußmann +7 more
openalex +1 more source
Indian Journal of Radiology and Imaging, 2006 Cerebral amyloid angiopathy (CAA) is a very rare entity. This is an age related disease and is not a manifestation of systemic amyloidosis in any of its forms. Sporadic cases are most common, though hereditary cases do exist. Alzheimer's disease predispose to CAA.
BKD Prasad, GS Kejriwal, SN Sahu
openaire +1 more source
Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.Abstract INTRODUCTION In Clarity AD, lecanemab reduced markers of amyloid in early symptomatic Alzheimer's disease and slowed cognitive and functional decline at 18 months. Herein, we report 36‐month data from the ongoing open‐label extension (OLE). METHODS Clarity AD is an 18‐month, randomized study (Core), with an OLE where participants received open‐
Christopher H. van Dyck +9 more
wiley +1 more source
Evaluation of Copper Chelation Therapy in a Transgenic Rat Model of Cerebral Amyloid Angiopathy
, 2023 Ashwin Ambi +6 more
openalex +2 more sources
Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum [PDF]
, 2005 In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease ...
Cruts, Marc +5 more
core +1 more source
CSF markers of vascular injury correlate with tau and cognitive decline in early Alzheimer's disease
Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.Abstract INTRODUCTION Cerebrovascular injury is common in Alzheimer's disease (AD), but its timing in relation to Aβ and tau pathology and cognitive decline remains unclear. METHODS We measured baseline vascular marker levels in cerebrospinal fluid (CSF) and serum from 75 Alzheimer's Disease Neuroimaging Initiative (ADNI) study participants, stratified
J. Scott Miners +3 more
wiley +1 more source