Results 101 to 110 of about 42,785 (261)

Intracranial Hemorrhage Due to Secondary Hypertension from Intracranial Large Vessel Occlusion [PDF]

, 2020
Simultaneous hemorrhagic and ischemic strokes have been previously reported in the literature. Typically, these occur in patients secondary to dialysis, cerebral amyloid angiopathy, or thrombotic thrombocytopenic purpura.1,2,3 However, this is the unique
Khan, Asif A., Rawal, Amit, Saeed, Omar, Waldman, Alex   +3 more
core  

Association of TDP-43 proteinopathy, cerebral amyloid angiopathy, and Lewy bodies with cognitive impairment in individuals with or without Alzheimer’s disease neuropathology

Scientific Reports, 2020
Alzheimer’s disease patients typically present with multiple co-morbid neuropathologies at autopsy, but the impact of these pathologies on cognitive impairment during life is poorly understood.
David X. Thomas, Sumali Bajaj, K. McRae-McKee, C. Hadjichrysanthou, Roy M. Anderson, J. Collinge   +5 more
semanticscholar   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Minocycline in Severe Cerebral Amyloid Angiopathy: A Single‐Center Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Evidence from animal studies suggests that minocycline may reduce lobar intracerebral hemorrhage (ICH) recurrence in cerebral amyloid angiopathy, possibly by inhibiting perivascular extracellular matrix degradation in cerebral small vessels ...
Francesco Bax, Andrew Warren, Avia Abramovitz Fouks, Hilde van den Brink, Susanne J. van Veluw, Mariel G. Kozberg, Steven M. Greenberg   +6 more
doaj   +1 more source

Blood-Brain Barrier Dysfunction in Small Vessel Disease Related Intracerebral Hemorrhage

Frontiers in Neurology, 2018
Background and Purpose: Hypertensive vasculopathy and cerebral amyloid angiopathy are the two most common forms of cerebral small vessel disease.
Whitney M. Freeze, Whitney M. Freeze, Heidi I. L. Jacobs, Heidi I. L. Jacobs, Floris H. B. M. Schreuder, Robert J. van Oostenbrugge, Walter H. Backes, Frans R. Verhey, Catharina J. M. Klijn   +8 more
doaj   +1 more source

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

The Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor, Miguel Martin‐Aragon Baudel, Eric Pereira da Silva, Johannes W. Hell, Madeline Nieves‐Cintron, Manuel F. Navedo   +5 more
wiley   +1 more source

Monoaminergic Neuropathology in Alzheimer's disease [PDF]

, 2016
Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira, Buée, Luc, Delalle, Ivana, Giovanni, Giuseppe Di, Harrington, Charles R., Hof, Patrick R., Jovanov-Milošević, Nataša, Leko, Mirjana Babić, Silva, Rohan de, Wischik, Claude M., Wray, Selina, Šimić, Goran   +11 more
core   +1 more source

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

Lancet Neurology, 2022
A. Charidimou, G. Boulouis, M. Frosch, J. Baron, M. Pasi, J. Albucher, G. Banerjee, Carmen Barbato, F. Bonneville, S. Brandner, L. Calvière, F. Caparros, B. Casolla, C. Cordonnier, M. Delisle, V. Deramecourt, M. Dichgans, E. Gokcal, J. Herms, M. Hernández-Guillamon, H. Jäger, Z. Jaunmuktane, J. Linn, S. Martinez-Ramirez, E. Martínez-Sáez, C. Mawrin, J. Montaner, S. Moulin, J. Olivot, F. Piazza, L. Puy, N. Raposo, M. Rodrigues, S. Roeber, J. R. Romero, N. Samarasekera, J. Schneider, S. Schreiber, F. Schreiber, Corentin Schwall, Colin Smith, L. Szalardy, P. Varlet, A. Viguier, J. Wardlaw, Andrew D. Warren, F. Wollenweber, M. Zedde, M. Buchem, M. Gurol, A. Viswanathan, R. Salman, E. Smith, D. Werring, S. Greenberg   +54 more
semanticscholar   +1 more source

Association of residential neighborhood disadvantage with amyloid PET positivity among cognitively impaired individuals

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 1, March 2026.
Abstract INTRODUCTION Relationships between Alzheimer's disease neuropathology, residential neighborhood, and cognitive impairment remain incompletely understood. METHODS We examined whether residence within a disadvantaged neighborhood was associated with amyloid positron emission tomography (PET) positivity.
Charles C. Windon, Elena Tsoy, Jennifer Livaudais‐Toman, Torsten B. Neilands, Nynikka R. Palmer, Margo B. Heston, Julene K. Johnson, Lucy Hanna, Constantine Gatsonis, Justin Romanoff, Jon Steingrimsson, Maria C. Carrillo, Peggye Dilworth‐Anderson, Bruce E. Hillner, Barry A. Siegel, Rachel A. Whitmer, Consuelo H. Wilkins, Karen Smith, Ganna Blazhenets, Renaud La Joie, Bruce L. Miller, Katherine L. Possin, Gil D. Rabinovici   +22 more
wiley   +1 more source

Endothelial Mitochondrial Dysfunction in Cerebral Amyloid Angiopathy and Alzheimer’s Disease

Journal of Alzheimer's Disease, 2019
Alzheimer’s disease (AD) is the most prevalent form of dementia. Cerebrovascular dysfunction is one of the earliest events in the pathogenesis of AD, as well as in vascular and mixed dementias. Cerebral amyloid angiopathy (CAA), the deposition of amyloid
Rebecca M Parodi-Rullán, J. Y. Sone, S. Fossati   +2 more
semanticscholar   +1 more source