Results 41 to 50 of about 42,785 (261)

Screening for Familial APP Mutations in Sporadic Cerebral Amyloid Angiopathy [PDF]

, 2010
Background Advances in genetic technology have revealed that variation in the same gene can cause both rare familial and common sporadic forms of the same disease.
A Rovelet-Lecrux, AL Gloyn, Alessandro Biffi, Anna Plourde, B Rosner, C Nilsberth, Christoph Winkler, Claudia M. Prada, D Woo, DA Nickerson, E Bakker, EE Smith, Eric E. Smith, James Gusella, JC Cohen, JC Florez, Jonathan Rosand, JP Vonsattel, KA Knudsen, L Hendriks, L Miravalle, L Obici, M Vaxillaire, Matthew Frosch, MS Fernando, Robert Onofrio, SM Greenberg, Steven M. Greenberg, SX Zhang-Nunes, TJ Grabowski, Yiping Shen, YW Chen   +31 more
core   +9 more sources

Cerebral amyloid angiopathy-related inflammation presenting with a stroke-like episode

European Journal of Case Reports in Internal Medicine, 2023
Cerebral amyloid angiopathy (CAA) is characterised by B-amyloid deposition in the walls of small to medium sized arteries of the cerebral cortex and the leptomeninges.
Ana Rita Gaspar, Catarina Faustino, Mara Sousa, Marta Valentim   +3 more
doaj   +1 more source

Volumetric analysis of carotid plaque components and cerebral microbleeds: a correlative study [PDF]

, 2017
PURPOSE: The purpose of this work was to explore the association between carotid plaque volume (total and the subcomponents) and cerebral microbleeds (CMBs).
Anzidei, Michele, DI MARTINO, Michele, Francone, Marco, Lucatelli, Pierleone, Montisci, Roberto, Porcu, Michele, Saba, Luca, Sanfilippo, Roberto, Suri, Jasjit S.   +8 more
core   +1 more source

Recurrent Subarachnoid Bleeding and Superficial Siderosis in a Patient with Histopathologically Proven Cerebral Amyloid Angiopathy

Case Reports in Neurology, 2011
A 68-year-old man with a history of hypertension presented with recurrent subarachnoid bleeding. Brain MRI showed superficial siderosis, and diagnostic cerebral angiograms did not show any intracranial vascular malformation or arterial aneurism.
P. Profice, F. Pilato, G. Della Marca, C. Colosimo, S. Gaudino, V. Arena, A. Pavone, V. Di Lazzaro   +7 more
doaj   +1 more source

Association Between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy-Related Inflammation.

JAMA Neurology, 2020
Importance Cerebral amyloid angiopathy-related inflammation (CAA-ri), a distinct subtype of cerebral amyloid angiopathy, is characterized by an autoimmune reaction to cerebrovascular β-amyloid deposits.
R. Regenhardt, Jesse M. Thon, Alvin S. Das, Olga R Thon, A. Charidimou, A. Viswanathan, M. Gurol, B. Chwalisz, M. Frosch, Tracey Cho, S. Greenberg   +10 more
semanticscholar   +1 more source

Cerebral Amyloid Angiopathy and the Fibrinolytic System: Is Plasmin a Therapeutic Target?

Stroke, 2021
Cerebral amyloid angiopathy is a devastating cause of intracerebral hemorrhage for which there is no specific secondary stroke prevention treatment. Here we review the current literature regarding cerebral amyloid angiopathy pathophysiology and treatment,
C. Mutimer, Charithani B. Keragala, H. Markus, D. Werring, G. Cloud, R. Medcalf   +5 more
semanticscholar   +1 more source

Cerebral Amyloid Angiopathy: Emerging Concepts [PDF]

Journal of Stroke, 2015
Cerebral amyloid angiopathy (CAA) involves cerebrovascular amyloid deposition and is classified into several types according to the amyloid protein involved.
Masahito Yamada
doaj   +1 more source

STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks

Acta Neuropathologica Communications, 2021
Previous reports indicate a potential role for signal transducer and activator of transcription 3 (STAT3) in amyloid-β (Aβ) processing and neuritic plaque pathogenesis.
J. Mehla, I. Singh, Deepti Diwan, James W. Nelson, Molly Lawrence, Eunjae Lee, A. Bauer, D. Holtzman, G. Zipfel   +8 more
semanticscholar   +1 more source

Convective infux/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways [PDF]

, 2018
Tracers injected into CSF pass into the brain alongside arteries and out again. This has been recently termed the "glymphatic system" that proposes tracers enter the brain along periarterial "spaces" and leave the brain along the walls of veins.
Albargothy, Nazira J., Carare, Roxana O., Hawkes, Cheryl A., Johnston, David A., MacGregor-Sharp, Matthew, Verma, Ajay, Weller, Roy O.   +6 more
core   +1 more source

Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo. [PDF]

, 2009
Amyloid imaging represents a major advance in neuroscience, enabling the detection and quantification of pathologic protein aggregations in the brain. In this review we survey current amyloid imaging techniques, focusing on positron emission tomography ...
Jagust, WJ, Rabinovici, GD
core   +2 more sources