Results 51 to 60 of about 32,043 (291)
Cerebral Amyloid Angiopathy-Related Inflammation following Multiple Cancers and Chemotherapies
Case Reports in Neurology, 2022 Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a rare autoimmune encephalopathy of aging caused by an autoantibody immune response against Aβ protein deposited in the brain of older adults affected by cerebral amyloid angiopathy (CAA) and ...
Christophe Severijns +3 more
doaj +1 more source
Solvent and mutation effects on the nucleation of amyloid $β$-protein folding [PDF]
, 2005 Experimental evidence suggests that the folding and aggregation of the amyloid $\beta$-protein (A$\beta$) into oligomers is a key pathogenetic event in Alzheimer's disease (AD). Inhibiting the pathologic folding and oligomerization of A$\beta$ could be effective in the prevention and treatment of AD.
arxiv +1 more source
Succinct Amyloid and Non-Amyloid Patterns in Hexapeptides [PDF]
arXiv, 2022 Hexapeptides are widely applied as a model system for studying amyloid-forming properties of polypeptides, including proteins. Recently, large experimental databases have become publicly available with amyloidogenic labels. Using these datasets for training and testing purposes, one may build artificial intelligence (AI)-based classifiers for ...
arxiv
Acceleration of amyloid fibril formation by multichannel sonochemical reactor [PDF]
, 2021 Formation of amyloid fibrils of various amyloidogenic proteins is dramatically enhanced by ultrasound irradiation. For applying this phenomenon to the study of protein aggregation science and diagnosis of neurodegenerative diseases, a multichannel ultrasound irradiation system with individually adjustable ultrasound-irradiation conditions is necessary.
arxiv +1 more source
Cerebral Amyloid Angiopathy and Blood-Brain Barrier Dysfunction
The Neuroscientist, 2020 Cerebral hemorrhage, a devastating subtype of stroke, is often caused by hypertension and cerebral amyloid angiopathy (CAA). Pathological evidence of CAA is detected in approximately half of all individuals over the age of 70 and is associated with ...
Monica Gireud-Goss +3 more
semanticscholar +1 more source
Advanced ScienceCerebral amyloid angiopathy (CAA) is the leading cause of vascular dementia among the elderly. Neuropsychiatric symptoms are commonly manifested in cerebral amyloid angiopathy patients but are usually considered as consequences of cerebral amyloid ...
Huipeng Huang +11 more
doaj +1 more source
Label free visualization of amyloid plaques in Alzheimer's disease with polarization-sensitive photoacoustic Mueller matrix tomography [PDF]
arXiv, 2022 The formation of amyloid plaques in the cortical and hippocampal brain regions caused by abnormal deposition of extracellular amyloid \b{eta}-protein (A\b{eta}) is a characteristic pathological hallmark of early Alzheimer's disease (AD), while label-free graphic rendering of diseased amyloid plaques in vivo is still a highly challenging task.
arxiv
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance We found an increased interaction between CAA-linked mutant Aβ and fibrin(ogen) that may not only result in severely altered fibrin structure and function but may also lead to vast amounts of fibrin(ogen)/Aβ codeposition, as well as fibrin ...
Steven A. Cajamarca +4 more
semanticscholar +1 more source
Cerebral Amyloid Angiopathy Is Associated With Higher R2 Relaxation Rate: An MRI and Pathology Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebral amyloid angiopathy (CAA) involves β‐amyloid deposition in the walls of cortical and leptomeningeal small vessels. Transverse relaxation rate (R2) is a major source of contrast in MRI. This study tested the hypothesis that CAA is associated with R2, extracted the spatial pattern of CAA‐related R2 abnormalities, and evaluated ...
Md Tahmid Yasar +6 more
wiley +1 more source
Неврология, нейропсихиатрия, психосоматика, 2020 Idiopathic normal pressure hydrocephalus (NPH) is cerebral ventriculomegaly characterized by a wide range of controversial issues related to the prevalence of the disease, the mechanisms of its development, and nosological independence. Developing in old
E. G. Mendelevich
doaj +1 more source