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A multi-modal parcellation of human cerebral cortex
Understanding the amazingly complex human cerebral cortex requires a map (or parcellation) of its major subdivisions, known as cortical areas. Making an accurate areal map has been a century-old objective in neuroscience.
Matthew F Glasser+2 more
exaly +2 more sources
Natural speech reveals the semantic maps that tile human cerebral cortex
The meaning of language is represented in regions of the cerebral cortex collectively known as the ‘semantic system’. However, little of the semantic system has been mapped comprehensively, and the semantic selectivity of most regions is unknown. Here we
Thomas L Griffiths+2 more
exaly +2 more sources
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex
Experimental models of the human brain are needed for basic understanding of its development and disease1. Human brain organoids hold unprecedented promise for this purpose; however, they are plagued by high organoid-to-organoid variability2,3.
Silvia Velasco+2 more
exaly +2 more sources
Expression of Fc-gamma receptor type Ⅰ in brain cortex of patients with Alzheimer's disease and the mouse model [PDF]
Objective To explore expression changes of high affinity IgG receptor Fc-gamma Ⅰ type(FcγRⅠ) in brain cortex of patients with Alzheimer's disease(AD). Methods Normal human brain tissue samples and brain tissue samples with neuropathological diagnosis of ...
SUN Jian-ru, QIU Wen-ying, QIAN Xiao-jing, MA Chao
doaj +1 more source
Development of visual response selectivity in cortical GABAergic interneurons
Excitatory neurons in the carnivore and primate visual cortex display orientation selectivity arranged in a modular fashion before the onset of visual experience, but the developmental timeline for visual response selectivity of inhibitory neurons is ...
Jeremy T. Chang, David Fitzpatrick
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Activity and Coupling to Hippocampal Oscillations of Median Raphe GABAergic Cells in Awake Mice
Ascending serotonergic/glutamatergic projection from the median raphe region (MRR) to the hippocampal formation regulates both encoding and consolidation of memory and the oscillations associated with them.
Marta Jelitai+4 more
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A connectomic study of a petascale fragment of human cerebral cortex
We acquired a rapidly preserved human surgical sample from the temporal lobe of the cerebral cortex. We stained a 1 mm3 volume with heavy metals, embedded it in resin, cut more than 5000 slices at ∼30 nm and imaged these sections using a high-speed ...
Alexander Shapson-Coe+28 more
semanticscholar +1 more source
Cajal-Retzius cells (CRs) are transient neurons, disappearing almost completely in the postnatal neocortex by programmed cell death (PCD), with a percentage surviving up to adulthood in the hippocampus. Here, we evaluate CR’s role in the establishment of
Martina Riva+20 more
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The mammalian cerebral cortex has changed significantly during evolution. As a result of the increase in the number of neurons and glial cells in the cerebral cortex, its size has markedly expanded. Moreover, folds, called gyri and sulci, appeared on its
Yohei Shinmyo+3 more
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Specific contribution of neurons from the Dbx1 lineage to the piriform cortex
The piriform cortex (PC) is a major cortical processing center for the sense of smell that receives direct inputs from the olfactory bulb. In mice, the PC consists of three neuronal layers, which are populated by cells with distinct developmental origins.
Thando Shabangu+5 more
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