Results 1 to 10 of about 1,141,462 (162)

A multi-modal parcellation of human cerebral cortex

open access: yesNature, 2016
Understanding the amazingly complex human cerebral cortex requires a map (or parcellation) of its major subdivisions, known as cortical areas. Making an accurate areal map has been a century-old objective in neuroscience.
Matthew F Glasser   +2 more
exaly   +2 more sources

Natural speech reveals the semantic maps that tile human cerebral cortex

open access: yesNature, 2016
The meaning of language is represented in regions of the cerebral cortex collectively known as the ‘semantic system’. However, little of the semantic system has been mapped comprehensively, and the semantic selectivity of most regions is unknown. Here we
Thomas L Griffiths   +2 more
exaly   +2 more sources

Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

open access: yesNature, 2019
Experimental models of the human brain are needed for basic understanding of its development and disease1. Human brain organoids hold unprecedented promise for this purpose; however, they are plagued by high organoid-to-organoid variability2,3.
Silvia Velasco   +2 more
exaly   +2 more sources

Expression of Fc-gamma receptor type Ⅰ in brain cortex of patients with Alzheimer's disease and the mouse model [PDF]

open access: yesJichu yixue yu linchuang, 2022
Objective To explore expression changes of high affinity IgG receptor Fc-gamma Ⅰ type(FcγRⅠ) in brain cortex of patients with Alzheimer's disease(AD). Methods Normal human brain tissue samples and brain tissue samples with neuropathological diagnosis of ...
SUN Jian-ru, QIU Wen-ying, QIAN Xiao-jing, MA Chao
doaj   +1 more source

Development of visual response selectivity in cortical GABAergic interneurons

open access: yesNature Communications, 2022
Excitatory neurons in the carnivore and primate visual cortex display orientation selectivity arranged in a modular fashion before the onset of visual experience, but the developmental timeline for visual response selectivity of inhibitory neurons is ...
Jeremy T. Chang, David Fitzpatrick
doaj   +1 more source

Activity and Coupling to Hippocampal Oscillations of Median Raphe GABAergic Cells in Awake Mice

open access: yesFrontiers in Neural Circuits, 2021
Ascending serotonergic/glutamatergic projection from the median raphe region (MRR) to the hippocampal formation regulates both encoding and consolidation of memory and the oscillations associated with them.
Marta Jelitai   +4 more
doaj   +1 more source

A connectomic study of a petascale fragment of human cerebral cortex

open access: yesbioRxiv, 2021
We acquired a rapidly preserved human surgical sample from the temporal lobe of the cerebral cortex. We stained a 1 mm3 volume with heavy metals, embedded it in resin, cut more than 5000 slices at ∼30 nm and imaged these sections using a high-speed ...
Alexander Shapson-Coe   +28 more
semanticscholar   +1 more source

Aberrant survival of hippocampal Cajal-Retzius cells leads to memory deficits, gamma rhythmopathies and susceptibility to seizures in adult mice

open access: yesNature Communications, 2023
Cajal-Retzius cells (CRs) are transient neurons, disappearing almost completely in the postnatal neocortex by programmed cell death (PCD), with a percentage surviving up to adulthood in the hippocampus. Here, we evaluate CR’s role in the establishment of
Martina Riva   +20 more
doaj   +1 more source

Investigation of the Mechanisms Underlying the Development and Evolution of the Cerebral Cortex Using Gyrencephalic Ferrets

open access: yesFrontiers in Cell and Developmental Biology, 2022
The mammalian cerebral cortex has changed significantly during evolution. As a result of the increase in the number of neurons and glial cells in the cerebral cortex, its size has markedly expanded. Moreover, folds, called gyri and sulci, appeared on its
Yohei Shinmyo   +3 more
doaj   +1 more source

Specific contribution of neurons from the Dbx1 lineage to the piriform cortex

open access: yesScientific Reports, 2021
The piriform cortex (PC) is a major cortical processing center for the sense of smell that receives direct inputs from the olfactory bulb. In mice, the PC consists of three neuronal layers, which are populated by cells with distinct developmental origins.
Thando Shabangu   +5 more
doaj   +1 more source

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