Results 1 to 10 of about 547,687 (344)

Expression of Fc-gamma receptor type Ⅰ in brain cortex of patients with Alzheimer's disease and the mouse model [PDF]

Jichu yixue yu linchuang, 2022
Objective To explore expression changes of high affinity IgG receptor Fc-gamma Ⅰ type(FcγRⅠ) in brain cortex of patients with Alzheimer's disease(AD). Methods Normal human brain tissue samples and brain tissue samples with neuropathological diagnosis of ...
SUN Jian-ru, QIU Wen-ying, QIAN Xiao-jing, MA Chao
doaj   +1 more source

Development of visual response selectivity in cortical GABAergic interneurons

Nature Communications, 2022
Excitatory neurons in the carnivore and primate visual cortex display orientation selectivity arranged in a modular fashion before the onset of visual experience, but the developmental timeline for visual response selectivity of inhibitory neurons is ...
Jeremy T. Chang, David Fitzpatrick
doaj   +1 more source

Activity and Coupling to Hippocampal Oscillations of Median Raphe GABAergic Cells in Awake Mice

Frontiers in Neural Circuits, 2021
Ascending serotonergic/glutamatergic projection from the median raphe region (MRR) to the hippocampal formation regulates both encoding and consolidation of memory and the oscillations associated with them.
Marta Jelitai, Albert M. Barth, Ferenc Komlósi, Tamás F. Freund, Viktor Varga   +4 more
doaj   +1 more source

Investigation of the Mechanisms Underlying the Development and Evolution of the Cerebral Cortex Using Gyrencephalic Ferrets

Frontiers in Cell and Developmental Biology, 2022
The mammalian cerebral cortex has changed significantly during evolution. As a result of the increase in the number of neurons and glial cells in the cerebral cortex, its size has markedly expanded. Moreover, folds, called gyri and sulci, appeared on its
Yohei Shinmyo, Toshihide Hamabe-Horiike, Kengo Saito, Hiroshi Kawasaki   +3 more
doaj   +1 more source

Aberrant survival of hippocampal Cajal-Retzius cells leads to memory deficits, gamma rhythmopathies and susceptibility to seizures in adult mice

Nature Communications, 2023
Cajal-Retzius neurons number drastically decreases during postnatal life. Here, authors show that their programmed death is required for the construction of functional hippocampal circuits and memory with aberrant survival leading to gamma rhythmopathies
Martina Riva, Stéphanie Moriceau, Annunziato Morabito, Elena Dossi, Candela Sanchez-Bellot, Patrick Azzam, Andrea Navas-Olive, Beatriz Gal, Francesco Dori, Elena Cid, Fanny Ledonne, Sabrina David, Fabrice Trovero, Magali Bartolomucci, Eva Coppola, Nelson Rebola, Antoine Depaulis, Nathalie Rouach, Liset Menendez de la Prida, Franck Oury, Alessandra Pierani   +20 more
doaj   +1 more source

A murine model of variant late infantile ceroid lipofuscinosis recapitulates behavioral and pathological phenotypes of human disease. [PDF]

, 2013
Neuronal ceroid lipofuscinoses (NCLs; also known collectively as Batten Disease) are a family of autosomal recessive lysosomal storage disorders.
Cooper, Jonathan D, Koch, Bettina, Magee, Helen, Morgan, Jeremy P, Nelson, Tarah, Weimer, Jill M, Wong, Andrew   +6 more
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Specific contribution of neurons from the Dbx1 lineage to the piriform cortex

Scientific Reports, 2021
The piriform cortex (PC) is a major cortical processing center for the sense of smell that receives direct inputs from the olfactory bulb. In mice, the PC consists of three neuronal layers, which are populated by cells with distinct developmental origins.
Thando Shabangu, Hung-Lun Chen, Zi-hui Zhuang, Alessandra Pierani, Chien-Fu F. Chen, Shen-Ju Chou   +5 more
doaj   +1 more source

Cerebral cortex and blood transcriptome changes in mouse neonates prenatally exposed to air pollution particulate matter

Journal of Neurodevelopmental Disorders, 2021
Background Prenatal exposure to air pollutants is associated with increased risk for neurodevelopmental and neurodegenerative disorders. However, few studies have identified transcriptional changes related to air pollutant exposure.
Amin Haghani, Jason I. Feinberg, Kristy C. Lewis, Christine Ladd-Acosta, Richard G. Johnson, Andrew E. Jaffe, Constantinos Sioutas, Caleb E. Finch, Daniel B. Campbell, Todd E. Morgan, Heather E. Volk   +10 more
doaj   +1 more source

Prenatal Neurogenesis in Autism Spectrum Disorders. [PDF]

, 2016
An ever-increasing body of literature describes compelling evidence that a subset of young children on the autism spectrum show abnormal cerebral growth trajectories.
Kaushik, Gaurav, Zarbalis, Konstantinos S   +1 more
core   +1 more source

Decreased density of pyramidal cells in the cerebral cortex, and Purkinje cells in the cerebellar cortex of Sprague-Dawley rats after being exposed to filtered kretek cigarette smoke

Journal of Biological Research, 2023
Filtered kretek cigarette smoke is a gas that contains solid components (particulates). Carcinogenic chemicals are present in this type of cigarette smoke. Furthermore, it is said that tobacco has a major negative impact on cerebral structure development,
David Tjahyadi, Edy Parwanto, Husnun Amalia, Reza Aditya Digambiro, Hosea Jaya Edy, Ashaolu Victoria Oladimeji   +5 more
doaj   +1 more source