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The major cell classes of the brain differ in their developmental processes, metabolism, signaling, and function. To better understand the functions and interactions of the cell types that comprise these classes, we acutely purified representative ...
Ye Zhang+16 more
semanticscholar +1 more source
A developmental and genetic classification for malformations of cortical development: update 2012. [PDF]
Malformations of cerebral cortical development include a wide range of developmental disorders that are common causes of neurodevelopmental delay and epilepsy. In addition, study of these disorders contributes greatly to the understanding of normal brain
Barkovich, A James+4 more
core +3 more sources
Multiple conserved regulatory domains promote Fezf2 expression in the developing cerebral cortex. [PDF]
BackgroundThe genetic programs required for development of the cerebral cortex are under intense investigation. However, non-coding DNA elements that control the expression of developmentally important genes remain poorly defined. Here we investigate the
Chen, Bin+8 more
core +4 more sources
Correlation between brain injury and dysphagia in adult patients with stroke
Introduction: In the literature, the incidence of oropharyngeal dysphagia in patients with cerebrovascular accident (AVE) ranges 20-90%. Some studies correlate the location of a stroke with dysphagia, while others do not.
Nunes, Maria Cristina de Alencar+6 more
doaj +3 more sources
Mapping the Structural Core of Human Cerebral Cortex
Structurally segregated and functionally specialized regions of the human cerebral cortex are interconnected by a dense network of cortico-cortical axonal pathways.
P. Hagmann+6 more
semanticscholar +1 more source
Hippocampal Network Dynamics during Rearing Episodes
Summary: Animals build a model of their surroundings on the basis of information gathered during exploration. Rearing on the hindlimbs changes the vantage point of the animal, increasing the sampled area of the environment.
Albert M. Barth+4 more
doaj +1 more source
IntroductionMultiple sclerosis (MS) affects the cerebral cortex, inducing cortical atrophy and neuronal and synaptic pathology. Despite the fact that women are more susceptible to getting MS, men with MS have worse disability progression.
Noriko Itoh+4 more
doaj +1 more source
We describe refinements in optogenetic methods for circuit mapping that enable measurements of functional synaptic connectivity with single-neuron resolution.
Christopher A Baker+3 more
doaj +1 more source
Co-transmission of acetylcholine and GABA regulates hippocampal states
Acetylcholine (ACh) release in the central nervous system is thought to be unitary and mediated non-synaptically in volume transmission. Here, Takács and colleagues show cholinergic terminals juxtapose GABAergic synapses anatomically and functionally ...
Virág T. Takács+10 more
doaj +1 more source
Application of digital terrain analysis to the study of cerebral cortex morphology
Objective·To propose a theoretical method based on geosciences for the expression and quantitative description of the surface morphology of the cerebral cortex.Methods·Eighty-five samples of normal cognition (NC) and 84 samples of Alzheimer′s disease (AD)
YANG Zihao, CHEN Nan, LIN Siwei
doaj +1 more source