Results 31 to 40 of about 1,244,067 (429)

An Evidence-Based Review of Related Metabolites and Metabolic Network Research on Cerebral Ischemia [PDF]

open access: yes, 2016
In recent years, metabolomics analyses have been widely applied to cerebral ischemia research. This paper introduces the latest proceedings of metabolomics research on cerebral ischemia.
Hao Zhan   +6 more
core   +2 more sources

Exercise preconditioning exhibits neuroprotective effects on hippocampal CA1 neuronal damage after cerebral ischemia

open access: yesNeural Regeneration Research, 2015
Recent evidence has suggested the neuroprotective effects of physical exercise on cerebral ischemic injury. However, the role of physical exercise in cerebral ischemia-induced hippocampal damage remains controversial.
Nabi Shamsaei   +4 more
doaj   +1 more source

Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]

open access: yes, 2004
Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and ...
Candelario-Jalil, Eduardo   +4 more
core   +1 more source

Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury [PDF]

open access: yesFrontiers in Aging Neuroscience, 2021
Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. In recent years, reperfusion treatments based on thrombolytic and thrombectomy are major managements for ischemic stroke patients, and the recanalization time window has been extended to over 24 h.
Chengmei Sun   +8 more
openaire   +4 more sources

Neuroprotective effect of baicalin on focal cerebral ischemia in rats

open access: yesNeural Regeneration Research, 2018
Baicalin, a flavonoid compound from the root of the herb Scutellaria baicalensis Georgi, has been widely used to treat patients with inflammatory disease.
Jiong Dai   +8 more
doaj   +1 more source

Barrier mechanisms in neonatal stroke. [PDF]

open access: yes, 2014
Clinical data continue to reveal that the incidence of perinatal stroke is high, similar to that in the elderly. Perinatal stroke leads to significant morbidity and severe long-term neurological and cognitive deficits, including cerebral palsy ...
Chip, Sophorn   +2 more
core   +2 more sources

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia

open access: yesNeural Regeneration Research, 2015
The Rho/Rho-kinase signaling pathway plays an important role in cerebral ischemia/reperfusion injury. However, very few studies have examined in detail the changes in the Rho/Rho-kinase signaling pathway in chronic cerebral ischemia.
Ya-yun Yan   +7 more
doaj   +1 more source

Early changes in transient adenosine during cerebral ischemia and reperfusion injury. [PDF]

open access: yesPLoS ONE, 2018
Adenosine is an important neuromodulator in the central nervous system, and tissue adenosine levels increase during ischemic events, attenuating excitotoxic neuronal injury.
Mallikarjunarao Ganesana, B Jill Venton
doaj   +1 more source

microRNA-455-5p alleviates neuroinflammation in cerebral ischemia/reperfusion injury

open access: yesNeural Regeneration Research, 2022
Neuroinflammation is a major pathophysiological factor that results in the development of brain injury after cerebral ischemia/reperfusion. Downregulation of microRNA (miR)-455-5p after ischemic stroke has been considered a potential biomarker and ...
Jian-Song Zhang   +10 more
doaj   +1 more source

CT Perfusion for Detection of Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis [PDF]

open access: yes, 2013
BACKGROUND AND PURPOSE: Delayed cerebral ischemia is a significant cause of morbidity and mortality after aneurysmal SAH, leading to poor outcomes. The purpose of this study was to evaluate the usefulness of CTP in determining delayed cerebral ischemia ...
Dunning, A.   +6 more
core   +3 more sources

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