Results 81 to 90 of about 1,244,067 (429)
The critical roles of mitophagy in cerebral ischemia
Protein & Cell, 2016 Mitochondria play a key role in various cell processes including ATP production, Ca2+ homeostasis, reactive oxygen species (ROS) generation, and apoptosis. The selective removal of impaired mitochondria by autophagosome is known as mitophagy.
Yan-Cheng Tang +3 more
semanticscholar +1 more source
Research progress of IGF‐1 and cerebral ischemia
Ibrain, 2021 Cerebral ischemic disease is a group of diseases that cause insufficient blood supply to the cerebrum, cerebellum or brain stem for different reasons, resulting in corresponding nervous system symptoms.
Shun‐Lian Li +3 more
doaj +1 more source
Protective Effect of Mesenchymal Stem Cells on Cerebral Ischemic Reperfusion Injury
Xiehe Yixue Zazhi, 2023 Cerebral ischemia-reperfusion injury, one of the main reasons for poor prognosis in patients with neurological diseases, is also an important cause of paralysis.
WANG Jie, LI Xiangmin
doaj +1 more source
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]
, 2007 Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition ...
Candelario-Jalil, Eduardo +4 more
core +2 more sources
Biomolecules & Therapeutics, 2016 Dexmedetomidine is an α2-adrenergic receptor agonist that exhibits a protective effect on ischemia-reperfusion injury of the heart, kidney, and other organs.
Li-jun Wang +5 more
semanticscholar +1 more source
Cerebral autoregulation in patients with acute lacunar infarction: a reliable predictor of outcome
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective To further investigate the association between dynamic cerebral autoregulation (dCA) and the outcomes in patients with acute lacunar infarction. Methods Patients were prospectively and consecutively enrolled at The First Hospital of Jilin University between 2016 and 2023. dCA was monitored at 1–3 and 7–10 days after the stroke.
Xiang‐Kun Si +7 more
wiley +1 more source
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Objective Patients with spontaneous subarachnoid hemorrhage (SAH) may develop refractory arterial cerebral vasospasm (CVS), which is the leading cause of death in SAH patients. This study explored the clinical diagnostic value of serum miR‐195‐5p levels in CVS after SAH (SAH + CVS) and its relationship with the prognosis of SAH + CVS.
Yong Li +3 more
wiley +1 more source
Higher ventricular rate during atrial fibrillation relates to increased cerebral hypoperfusions and hypertensive events [PDF]
Scientific Reports, 9: 3779, 2019, 2019 Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events; however, it is presently unknown, if ventricular response rate during AF may impact on cerebral hemodynamics.
arxiv +1 more source
Stroke, 2012 Background and Purpose— Mononuclear phagocytes are highly plastic cells that assume diverse phenotypes in response to microenvironmental signals. The phenotype-specific roles of microglia/macrophages in ischemic brain injury are poorly understood.
Xiaoming Hu +7 more
semanticscholar +1 more source
CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh +8 more
wiley +1 more source