Results 81 to 90 of about 1,282,370 (257)

Expensive cerebral blood flow measurements alone are useless and misinformative in comatose patients: a comprehensive alternative [PDF]

Arquivos de Neuro-Psiquiatria, 2003
Since the first report addressing quantification of cerebral blood flow (CBF), concomitant assessment of cerebral oxygen consumption was also carried out.
Julio Cruz
doaj   +1 more source

Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats [PDF]

, 2003
Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury.
Candelario-Jalil, Eduardo, Garcia-Cabrera, Michel, Gonzalez-Falcon, Armando, Leon, Olga S.   +3 more
core  

The Structural Features of Vascular Endothelium in Acute Cerebral Ischemia [PDF]

, 2017
The aim of the research was to study the number and structural properties of desquamated endothelial cells (DECs) in the peripheral blood in carotid ischemic stroke (CIS) and carotid transient ischemic attacks (TIAs) and its connection with the marker of
Kosheleva, A. (Anna)
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DPP-4 inhibition with linagliptin ameliorates cognitive impairment and brain atrophy induced by transient cerebral ischemia in type 2 diabetic mice

Cardiovascular Diabetology, 2015
BackgroundIt is unclear whether dipeptidylpeptidase-4 (DPP-4) inhibition can counteract the impairment of cognitive function and brain injury caused by transient cerebral ischemia in type 2 diabetes.
Mingjie Ma, Yu Hasegawa, Nobutaka Koibuchi, Kensuke Toyama, Ken Uekawa, Takashi Nakagawa, Bowen Lin, S. Kim‐Mitsuyama   +7 more
semanticscholar   +1 more source

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

Neural Regeneration Research
Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient’s condition; this phenomenon is known as cerebral ischemia-reperfusion injury.
Zi Ye, Runqing Liu, Hangxing Wang, Aizhen Zuo, Cen Jin, Nan Wang, Huiqi Sun, Luqian Feng, Hua Yang   +8 more
doaj   +1 more source

Effect of Saponin on Cerebral Edema Rate in An Animal Model of Stroke

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Oxidative stress and neuroinflammation are the main causes of cerebral ischemia. Saponin with steroid or triterpenoid compounds with a sugar part has strong antioxidant and anti-inflammatory properties.
Elmira Shiri, Mohammad Reza Bigdeli, Akram Eidi, Seyed Pejman Mortazavi   +3 more
doaj  

A depletable pool of adenosine in area CA1 of the rat hippocampus [PDF]

, 2001
Adenosine plays a major modulatory and neuroprotective role in the mammalian CNS. During cerebral metabolic stress, such as hypoxia or ischemia, the increase in extracellular adenosine inhibits excitatory synaptic transmission onto vulnerable neurons via
Caldwell, Darren, Dale, Nicholas, Frenguelli, Bruno G., Nuritova, Feruza, Pearson, Tim   +4 more
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The Roles of High Mobility Group Box 1 in Cerebral Ischemic Injury

Frontiers in Cellular Neuroscience, 2020
High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that plays an important role in stabilizing nucleosomes and DNA repair. HMGB1 can be passively released from necrotic neurons or actively secreted by microglia, macrophages/monocytes, and ...
Xiaoyun Gou, Xiaoyun Gou, Junjie Ying, Junjie Ying, Yan Yue, Yan Yue, Xia Qiu, Xia Qiu, Peng Hu, Peng Hu, Yi Qu, Yi Qu, Jinhui Li, Jinhui Li, Dezhi Mu, Dezhi Mu   +15 more
doaj   +1 more source

The future of ischemic stroke: flow from prehospital neuroprotection to definitive reperfusion. [PDF]

, 2014
Recent advances in ischemic stroke enable a seamless transition of the patient flow from the prehospital setting to definitive reperfusion, without the arbitrary separation of therapeutic phases of ischemia based on time alone.
Ip, Hing Lung, Liebeskind, David S
core   +1 more source

Salidroside ameliorates cerebral ischemic injury and regulates the glutamate metabolism pathway in astrocytes

Frontiers in Pharmacology
Background and AimSalidroside (SA) is the main active component of Rhodiola rosea L., with potential in treating cardiovascular and cerebrovascular diseases and cerebral ischemia.
Xiaoyu Zheng, Hongwei Zhang, Hongwei Zhang, Yehao Zhang, Zhao Ding, Zishan Huang, Zishan Huang, Haoran Li, Haoran Li, Mingjiang Yao, Wenting Song, Jianxun Liu   +11 more
doaj   +1 more source