Results 101 to 110 of about 28,910 (233)

The Case for the Use of PPARγ Agonists as an Adjunctive Therapy for Cerebral Malaria

PPAR Research, 2012
Cerebral malaria is a severe complication of Plasmodium falciparum infection associated with high mortality even when highly effective antiparasitic therapy is used.
Lena Serghides
doaj   +1 more source

Modulation of cerebral malaria by curcumin as an adjunctive therapy

Brazilian Journal of Infectious Diseases, 2013
Cerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually.
Kunal Jain, Sumeet Sood, K. Gowthamarajan   +2 more
doaj   +1 more source

Evolution of Resistance to Avian Malaria Infection in an Endemic Hawaiian Honeycreeper

Ecology and Evolution, Volume 16, Issue 5, May 2026.
Hawaiian honeycreepers, a group of endemic song birds, represent one of the most stunning examples of an adaptive radiation. An evolutionary history devoid of malaria‐causing parasites has made them incredibly susceptible to disease. This work sought to identify genomic correlates of avian malaria infection.
John H. Neddermeyer, Loren Cassin‐Sackett, Eben H. Paxton, Michael G. Campana, Robert C. Fleischer, Jeffrey T. Foster   +5 more
wiley   +1 more source

Comparison of all-cause and malaria-specific mortality from two West African countries with different malaria transmission patterns. [PDF]

, 2008
BACKGROUND: Malaria is a leading cause of death in children below five years of age in sub-Saharan Africa. All-cause and malaria-specific mortality rates for children under-five years old in a mesoendemic malaria area (The Gambia) were compared with ...
Ndugwa, Robert P, Heribert Ramroth, Ali Sié, Momodou Jasseh, Olaf Müller, Bocar Kouyaté, Jasseh, Momodou, Sié, Ali, Robert P Ndugwa, Müller, Olaf, Ramroth, Heribert, Heiko Becher, Becher, Heiko, Kouyaté, Bocar, Greenwood, Brian, Brian Greenwood   +15 more
core   +1 more source

IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain.

, 2012
It is well established that IFN-γ is required for the development of experimental cerebral malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the temporal and tissue-specific cellular sources of IFN-γ during P.
Hunter, Christopher A, Couper, Kevin N, Riley, Eleanor M, Greig, Rachel, Blount, Daniel G, Blount, Daniel G., Stumhofer, Jason S, Hafalla, Julius CR, De Souza, J. Brian, Findlay, Emily Gwyer, Shaw, Tovah N, de Souza, J Brian, Riley, Eleanor M., Shaw, Tovah N., Stumhofer, Jason S., Hunter, Christopher A., Hafalla, Julius C R, Couper, Kevin N., Gwyer Findlay, Emily, Villegas-Mendez, Ana   +19 more
core   +1 more source

Influences of intermittent preventive treatment and persistent multiclonal Plasmodium falciparum infections on clinical malaria risk. [PDF]

, 2010
BACKGROUND: Intermittent preventive treatment (IPT) of malaria involves administration of curative doses of antimalarials at specified time points to vulnerable populations in endemic areas, regardless whether a subject is known to be infected.
Färnert, Anna, Kweku Margaret, Olsson Daniel, Daniel Olsson, Kweku, Margaret,, Daniel Chandramohan, Margaret Kweku, Chandramohan, Daniel,, Montgomery, Scott M.,, Montgomery, Scott M, Scott M. Montgomery, Liljander Anne, Liljander, Anne,, Greenwood, Brian,, Greenwood, Brian, Brian Greenwood, Kweku, Margaret, Chandramohan Daniel, Montgomery Scott M., Olsson, Daniel,, Greenwood Brian, Anna Färnert, Färnert, Anna,, Chandramohan, Daniel, Scott M Montgomery, Liljander, Anne, Anne Liljander, Färnert Anna, Olsson, Daniel   +28 more
core   +1 more source

Cerebral malaria.

Journal of neurology, neurosurgery, and psychiatry, 2000
Cerebral malaria may be the most common non-traumatic encephalopathy in the world. The pathogenesis is heterogeneous and the neurological complications are often part of a multisystem dysfunction. The clinical presentation and pathophysiology differs between adults and children.
Newton, CRJC, Hien, TT, White, N
openaire   +2 more sources

samkioko/Cerebral-malaria-EV-RNAseq: v2

<p>These customised R scripts were used to analyse the RNA content of extracellular vesicles obtained from plasma of cerebral malaria patients</p ...
samkioko
core   +1 more source

Activation of transforming growth factor beta by malaria parasite-derived metalloproteinases and a thrombospondin-like molecule [PDF]

, 2003
Much of the pathology of malaria is mediated by inflammatory cytokines (such as interleukin 12, interferon gamma, and tumor necrosis factor alpha), which are part of the immune response that kills the parasite.
Riley, Eleanor M, Sultan, Ali A, J. Brian de Souza, de Souza, J Brian, Eleanor M. Riley, Corran, Patrick H, Patrick H. Corran, Omer, Fakhreldin M, Riley, EM, Sultan, AA, Corran, PH, Ali A. Sultan, Omer, FM, de Souza, JB, Fakhreldin M. Omer   +14 more
core   +1 more source

Murine malaria is associated with significant hearing impairment

Malaria Journal, 2010
Background Plasmodium falciparum malaria has been suspected to cause hearing loss. Developmental, cognitive and language disorders have been observed in children, surviving cerebral malaria.
Stephan Kurt, Reindl Markus, Glueckert Rudolf, Fischer Marlene, Dietmann Anelia, Lackner Peter, Kositz Christian H, Schmutzhard Joachim, Riechelmann Herbert, Schrott-Fischer Annelies, Schmutzhard Erich   +10 more
doaj   +1 more source