Results 91 to 100 of about 28,910 (233)
Human cerebral malaria and
Background Cerebral malaria, a severe form of Plasmodium falciparum infection, is an important cause of mortality in sub-Saharan African children.
Milner Danny A +21 more
doaj +1 more source
Acute Pancreatitis as an Extrahepatic Complication of Acute Hepatitis E Infection: A Case Report
ABSTRACT Clinicians should consider Hepatitis E Virus (HEV) a rare but significant etiology alongside established primary triggers, including gallstones and alcohol. Early HEV screening for hepatic and pancreatic dysfunction is required to improve care and avoid unnecessary interventions, especially in endemic regions.
Syed Abdur Rehman Shah +4 more
wiley +1 more source
CR1 Knops blood group alleles are not associated with severe malaria in the Gambia
The Knops blood group antigen erythrocyte polymorphisms have been associated with reduced falciparum malaria-based in vitro rosette formation (putative malaria virulence factor).
D T McNamara +20 more
core +1 more source
HMOX1 gene promoter alleles and high HO-1 levels are associated with severe malaria in Gambian children. [PDF]
Heme oxygenase 1 (HO-1) is an essential enzyme induced by heme and multiple stimuli associated with critical illness. In humans, polymorphisms in the HMOX1 gene promoter may influence the magnitude of HO-1 expression.
Madi Njie (177625) +101 more
core +1 more source
Epidemiological, clinical and therapeutic aspects of cerebral malaria imported in Albania
This is a case-report of two patients with cerebral malaria (CM) imported from West-African countries. Notably, this form of malaria was developed as a second disease episode, while the first episode was experienced in West Africa. These findings suggest
Arben Ndreu +9 more
doaj +1 more source
EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.
Disruption of blood-brain barrier (BBB) function is a key feature of cerebral malaria. Increased barrier permeability occurs due to disassembly of tight and adherens junctions between endothelial cells, yet the mechanisms governing junction disassembly ...
Thayer K Darling +9 more
doaj +1 more source
Each year approximately 300 million people are affected by malaria with over 1 million deaths in Africa Asia Oceania and South America attributable to malaria. Malaria is the most important of the parasitic diseases of human beings especially for those people living in sub-Saharan Africa where about 90%of deaths from malaria occur.
M A, Okunlola +2 more
openaire +2 more sources
Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco +17 more
wiley +1 more source
Malaria in pregnancy is one of the major causes of maternal morbidity worldwide, and leads to poor birth outcomes. There is a complex interaction between pregnancy and parasite-all favour the parasite and disadvantage the pregnant woman.
Jesus R. Alvarez +6 more
core +1 more source
Estimating the potential public health impact of seasonal malaria chemoprevention in African children. [PDF]
Seasonal malaria chemoprevention, previously known as intermittent preventive treatment in children, is highly effective in areas with a short malaria transmission season.
Greenwood, Brian M +15 more
core +1 more source

