Results 81 to 90 of about 1,645,602 (269)

Comparison of CD8+ T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria

Frontiers in Immunology, 2019
CD8+ T cells have been shown to play a critical role in the pathogenesis of experimental cerebral malaria (ECM) in mice, but their role in development of human cerebral malaria (HCM) remains unclear.
Valentina Barrera, Michael J. Haley, Patrick Strangward, E. Attree, S. Kamiza, K. Seydel, T. Taylor, D. Milner, A. Craig, Kevin N. Couper   +9 more
semanticscholar   +1 more source

Epidemiology and the Burden of malaria in Mozambique, The [PDF]

, 2006
[eng] Malaria occurs mostly in the tropical regions of the world. Sub-Saharan Africa is the area most affected. The occurrence of a very efficient mosquito vectors Anopheles gambiae complex and Anopheles funestus group sustain high transmission of the ...
Mabunda, Samuel José Alvés
core   +5 more sources

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

Phytotherapy Research, EarlyView.
ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley   +1 more source

The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development

Cell Reports, 2019
Summary Malaria represents a major cause of death from infectious disease. Hemozoin is a Plasmodium-derived product that contributes to progression of cerebral malaria.
M. Raulf, T. Johannssen, Svea Matthiesen, K. Neumann, S. Hachenberg, S. Mayer-Lambertz, F. Steinbeis, J. Hegermann, P. Seeberger, W. Baumgärtner, C. Strube, J. Ruland, B. Lepenies   +12 more
semanticscholar   +1 more source

CR1 Knops blood group alleles are not associated with severe malaria in the Gambia [PDF]

, 2003
The Knops blood group antigen erythrocyte polymorphisms have been associated with reduced falciparum malaria-based in vitro rosette formation (putative malaria virulence factor).
D T McNamara, McNamara, D T, Moulds, JM, Kasehagen, LJ, Zimmerman, P A, J Alexandra Rowe, Hill, Adrian, Zimmerman, PA, McNamara, DT, A V S Hill, Fitness, J, P A Zimmerman, J M Moulds, Moulds, J M, Rowe, J Alexandra; id_orcid, Hill, A V S, L J Kasehagen, J Fitness, Kasehagen, L J, Rowe, JA, Hill, AV   +20 more
core   +1 more source

A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population

Malaria Journal, 2009
Background Interleukin-12 (IL-12), a heterodimeric cytokine composed of p35 and p40 subunits, has been thought to play an important role in the pathogenesis of malaria. The IL-12p40 subunit is encoded by the IL12B gene.
Tsuchiya Naoyuki, Hananantachai Hathairad, Tokunaga Katsushi, Patarapotikul Jintana, Naka Izumi, Ohashi Jun   +5 more
doaj   +1 more source

Angiotensin II Moderately Decreases Plasmodium Infection and Experimental Cerebral Malaria in Mice. [PDF]

PLoS ONE, 2015
Angiotensin II, a peptide hormone that regulates blood pressure, has been proposed as a protective factor against cerebral malaria based on a genetic analysis.
Julio Gallego-Delgado, Charlotte Baravian, Innocent Edagha, Maureen C Ty, Marta Ruiz-Ortega, Marta Ruiz-Ortega, Wenyue Xu, Ana Rodriguez   +7 more
doaj   +1 more source

Molecular characterization of CD36 deficiency in blood donors of Middle Eastern and African origin reveals transcript‐level defects beyond genomic variants

Transfusion, EarlyView.
Abstract Background The increasing diversity of blood donor populations has created new challenges for transfusion services worldwide. The identification of donors lacking relevant high‐prevalence antigens is becoming increasingly important to ensure compatible blood products for alloimmunized patients and to support the development of rare donor ...
Sarah Petermann, Inga Stellmacher, Brigitte K. Flesch, Tanja Rehling, Irina Häcker, Marc F. Schetelig, Alexander Carbol, Lambros Kordelas   +7 more
wiley   +1 more source

Cerebral Malaria

Jurnal Biologi Tropis, 2023
Cerebral malaria is the worst complication of malaria caused by Plasmodium spp. This disease is spread in tropical and subtropical countries and can attack all age groups and genders. The peak incidence occurs in preschool children and very often causes death in children.
Dinda Salsabila, Alifia Mawadddah, Athalitha Andhera Nabil, Baiq Ramdhani Amelia Negara, Herdiana Nurul Utami, Indri Setiawati, Ni Nyoman Geriputri   +6 more
openaire   +1 more source

Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement. [PDF]

, 2012
In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered
Pan-Ngum Wirichada, George Mtove (124816), Gesase Samwel, Woodrow, Charles, Saiwaew, Somporn, Mwanga-Amumpaire Juliet, Fanello, CI, Kathryn Maitland, Ermelinda Gomes, Sarah Joseph (140503), White, Lisa, Nicholas J. White (35779), Ilse C E Hendriksen, Arjen M Dondorp, Gomes, Ermelinda, Samwel Gesase, Charles Woodrow, Sue J. Lee (140486), Rasaq Olaosebikan, Kesinee Chotivanich (140505), Fanello, Caterina I, Nicholas J White, Hendriksen Ilse C. E., White Nicholas J., von Seidlein Lorenz, Tshefu, Antoinette K, Antoinette K. Tshefu (140488), Sarah Joseph, von Seidlein, Lorenz, Antoinette K Tshefu, Lee, Sue, Silamut, Kamolrat, Tshefu Antoinette K., Woodrow, C, Corine Karema (140493), Ilse C. E. Hendriksen (140479), Mwanga-Amumpaire, J, Day Nicholas P. J., White Lisa J., White, Nicholas J, Caterina I. Fanello (140506), Maitland, K, Lee Sue J., Nicholas P J Day, Dondorp, Arjen M, Kamolrat Silamut (140501), Maitland Kathryn, Woodrow Charles, Dondorp, Adrianus, Arjen M. Dondorp (140509), Reyburn, Hugh, Day, Nicholas P J, Tshefu, AK, Day, Nicholas, Sue J Lee, Corine Karema, Juliet Mwanga-Amumpaire (140482), White, NJ, Lorenz von Seidlein (45473), Amos Ben, White, Lisa J, Lisa J White, Maitland, Kathryn, Amos, Ben, Somporn Saiwaew (140495), Silamut Kamolrat, Olaosebikan, Rasaq, Gomes, E, Lorenz von Seidlein, Pan-Ngum, W, Mtove, G, Samwel Gesase (140499), Hendriksen, ICE, Wirichada Pan-Ngum (2583205), Nicholas P. J. Day (35781), George Mtove, Joseph, Sarah, Gesase, Samwel, Hendriksen, IC, Chotivanich Kesinee, Saiwaew, S, Lisa J. White (101780), Hendriksen, Ilse C E, von Seidlein, L, Fanello Caterina I., Hugh Reyburn (45198), Reyburn Hugh, Juliet Mwanga-Amumpaire, Charles Woodrow (140489), Hendriksen, AM, Ben Amos (140491), Lee, Sue J, Gomes Ermelinda, Chotivanich, Kesinee, Wirichada Pan-Ngum, White, Nicholas, White, LJ, Ben Amos, Dondorp, AM, Gesase, S, Pan-Ngum, Wirichada, Mwanga-Amumpaire, Juliet, Amos, B, Karema, C, Day, NP, Joseph, S, Day, NPJ, Karema Corine, Saiwaew Somporn, Joseph Sarah, Karema, Corine, Lee, SJ, Chotivanich, K, Ermelinda Gomes (140497), Somporn Saiwaew, Kamolrat Silamut, Reyburn, H, Hugh Reyburn, Kesinee Chotivanich, Rasaq Olaosebikan (130780), Olaosebikan Rasaq, Kathryn Maitland (21356), Dondorp Arjen M., Silamut, K, Mtove George, Olaosebikan, R, Mtove, George, Caterina I Fanello   +127 more
core   +1 more source