Results 71 to 80 of about 1,645,602 (269)

Gene expression profiling in blood from cerebral malaria patients and mild malaria patients living in Senegal

BMC Medical Genomics, 2019
Background Plasmodium falciparum malaria remains a major health problem in Africa. The mechanisms of pathogenesis are not fully understood. Transcriptomic studies may provide new insights into molecular pathways involved in the severe form of the disease.
Alassane Thiam, Michel Sanka, Rokhaya Ndiaye Diallo, Magali Torres, Babacar Mbengue, Nicolas Fernandez Nunez, Fatou Thiam, Gora Diop, Geneviève Victorero, Catherine Nguyen, Alioune Dieye, Pascal Rihet   +11 more
doaj   +1 more source

Evaluating predictive values of umbilical cord arterial lactate for adverse newborn outcomes among term‐births in northern Uganda: A cross sectional analytical study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 408-420, April 2025.
Abstract Objective Birth asphyxia is one of the leading causes of death for neonates worldwide. Lack of an objective cost effective test to predict poor newborn outcomes at birth affects the ability to respond appropriately. This study determined predictive values of umbilical cord arterial lactate in relation to adverse neonatal outcomes. Methods This
Elizabeth Ayebare, James K. Tumwine, Jolly Nankunda, Anna Hjelmstedt, Wibke Jonas, Grace Ndeezi, Nicola Orsini, Claudia Hanson   +7 more
wiley   +1 more source

Estados alterados de la conciencia tras un daño cerebral [PDF]

, 2021
Las personas somos conscientes de nosotras mismas y de nuestro entorno a través de la conciencia. No obstante, los estados alterados de la conciencia son situaciones como el coma u otros estados clínicos en los que personas con un daño cerebral severo no
Federación Española de Daño Cerebral
core  

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Cerebral Malaria in Mouse and Man

Frontiers in Immunology, 2018
Cerebral malaria (CM) is an acute encephalopathy caused by the malaria parasite Plasmodium falciparum, which develops in a small minority of infected patients and is responsible for the majority of deaths in African children.
Nazanin Ghazanfari, Scott N. Mueller, W. Heath   +2 more
semanticscholar   +1 more source

Cuaderno técnico. Defensa de derechos de las personas con daño cerebral y sus familias [PDF]

, 2022
Las personas con daño cerebral y sus familias en ocasiones ven vulnerados sus derechos ante la falta de información sociosanitaria y ante la existencia limitada de recursos especializados en el ámbito educativo, sanitario o laboral; entre otros.
Federación Española de Daño Cerebral
core  

Differences in gene transcriptomic pattern of Plasmodium falciparum in children with cerebral malaria and asymptomatic carriers. [PDF]

PLoS ONE, 2014
The mechanisms underlying the heterogeneity of clinical malaria remain largely unknown. We hypothesized that differential gene expression contributes to phenotypic variation of parasites which results in a specific interaction with the host, leading to ...
Talleh Almelli, Grégory Nuel, Emmanuel Bischoff, Agnès Aubouy, Mohamed Elati, Christian William Wang, Marie-Agnès Dillies, Jean-Yves Coppée, Georges Nko Ayissi, Leonardo Kishi Basco, Christophe Rogier, Nicaise Tuikue Ndam, Philippe Deloron, Rachida Tahar   +13 more
doaj   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Malaria Policy Advisory Committee to the WHO : conclusions and recommendations of March 2013 meeting [PDF]

, 2013
The Malaria Policy Advisory Committee to the World Health Organization met in Geneva, Switzerland from 13 to 15 March, 2013. This article provides a summary of the discussions, conclusions and recommendations from that meeting.Meeting sessions included ...
WHO Malaria Policy Advisory Committee and Secretariat,, WHO Malaria Policy Advisory Committee and Secretariat   +1 more
core   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source