Results 241 to 250 of about 98,582 (280)

Dysregulated TIE‐2 expression is associated with blood‐brain barrier leakiness and Alzheimer's disease‐related neuropathology

Brain Pathology, EarlyView.
Ince et al., have analysed TIE‐1 and ‐2 expression in human brain tissue, including microvessel‐enriched fractions (MVF) and covering a spectrum of AD‐associated pathology, and in CSF from independent cohorts spanning a clinical spectrum from normal cognition to AD.
Selvi Ince, Carol Van Hulle, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Carey Gleason, Barbara B. Bendlin, Ozioma Okonkwo, Sanjay Asthana, Kaj Blennow, Henrik Zetterberg, Sterling C. Johnson, Seth Love, J. Scott Miners   +12 more
wiley   +1 more source

Tongxinluo capsule in the treatment of cerebral small vessel disease: protocol of a randomised, double-blind, placebo-controlled, multicentre clinical study (TOPS-CSVD). [PDF]

Stroke Vasc Neurol
Wang Y, Xie X, Xu J, Lei P, Wang K, Zhang J, Yu J, Cui M, Dong Q.   +8 more
europepmc   +1 more source

Wasteosomes accumulate in periventricular white matter hyperintensities and exhibit complex relationships with mixed pathology, sclerotic index, and perivascular space

Brain Pathology, EarlyView.
In a mixed diagnostic cohort of pathologically diagnosed Alzheimer's disease, cerebrovascular disease, mixed pathology, and control tissue, we connected the histopathological wasteosome profile in periventricular (PV) brain sections to 7T FLAIR‐MRI confirmed PV white matter hyperintensities (WMHs), vascular stenosis and perivascular space size ...
Nikita Ollen‐Bittle, Isabella Boesgaard, Austyn Roseborough, Meaghan Frank, Qi Zhang, Stephen H. Pasternak, Robert Hammond, Shawn N. Whitehead   +7 more
wiley   +1 more source

Siltation and tidal effects: a comprehensive, clinical, and didactic approach to reasoning about vertebrobasilar hypoflow conditions. [PDF]

Braz J Otorhinolaryngol
Neto ACL, Mezzalira R, Bittar RSM.
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

"Double Trouble": Ultra-Early Formation and Rupture of a De Novo Terminal Basilar Artery Aneurysm After Aneurysmal Subarachnoid Hemorrhage. [PDF]

Vasc Health Risk Manag
Wang Y, Chen F, Chen H, Zhang L.
europepmc   +1 more source

Circulating proteins and risk of small vessel stroke: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Gao Z, Xu Y, Chen Y, Kang D, Lin Y, Yao P.   +5 more
europepmc   +1 more source

CerebrAlcare Pills on CereBral Small VesseL DiseasE (CABLE) trial: rationale and design. [PDF]

Stroke Vasc Neurol
Zhou M, Gong Y, Han S, Wang M, Gu W, Chen HS, Zheng W, Feng K, Wang D, Li H, Zheng Z, Pan Y, Chen W, Wang Y.   +13 more
europepmc   +1 more source

Interactions between blood pressure variability, cerebral autoregulation, and covert cerebral small vessel disease in relation to cognitive performance in community-dwelling older adults. [PDF]

Alzheimers Dement
Chi NF, Peng LN, Lin CJ, Cheng HM, Chen CH, Wang PN, Chung CP.   +6 more
europepmc   +1 more source

Editorial: Vascular diseases of the brain: insights, progress and lessons learned. [PDF]

Front Neurol
Rehwald R, Sudre CH, Vilela PL, Jäger HR.   +3 more
europepmc   +1 more source