Results 81 to 90 of about 212,620 (328)

Vascular dementia: Current concepts and nomenclature harmonization. [PDF]

, 2012
Several types of cerebrovascular lesions are associated with cognitive decline, but the role of each type in dementia manifestation has yet to be determined.
Grinberg, Lea Tenenholz
core  

microRNA expression in peripheral blood cells following acute ischemic stroke and their predicted gene targets. [PDF]

, 2014
BackgroundmicroRNA (miRNA) are important regulators of gene expression. In patients with ischemic stroke we have previously shown that differences in immune cell gene expression are present.
Ander, Bradley P, Jickling, Glen C, Liu, Dazhi, Noblett, Dylan, Stamova, Boryana, Zhan, Xinhua   +5 more
core   +3 more sources

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Progressive Cerebral Small Vessel Disease Caused by an Autoimmune Response to Intravesical Bacille-Calmette-Guérin Treatment

Frontiers in Neurology, 2020
Systemic BCGitis and autoimmune diseases are possible adverse events of intravesical Bacille Calmette-Guérin-(BCG)-instillations in the treatment of urothelioma cancer.
Anouck Becker, Iris Quasar Grunwald, Iris Quasar Grunwald, Marcus M. Unger, Stefanie Behnke, Joerg Spiegel, Umut Yilmaz, Silke Walter, Silke Walter, Klaus Faßbender   +9 more
doaj   +1 more source

Genetics of Cerebral Small Vessel Disease [PDF]

Journal of Stroke, 2015
Cerebral small vessel disease (SVD) is an important cause of stroke and cognitive impairment among the elderly and is a more frequent cause of stroke in Asia than in the US or Europe. Although traditional risk factors such as hypertension or diabetes mellitus are important in the development of cerebral SVD, the exact pathogenesis is still uncertain ...
openaire   +3 more sources

Cerebral Amyloid and Hypertension are Independently Associated with White Matter Lesions in Elderly. [PDF]

, 2015
In cognitively normal (CN) elderly individuals, white matter hyperintensities (WMH) are commonly viewed as a marker of cerebral small vessel disease (SVD).
Alzheimer’s Disease Neuroimaging Initiative, Braskie, Meredith N, Carmichael, Owen T, DeCarli, Charles, Scott, Julia A, Thompson, Paul M, Tosun, Duygu, Weiner, Michael   +7 more
core   +2 more sources

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Imaging-validated correlates and implications of the pathophysiologic mechanisms of ageing-related cerebral large artery and small vessel diseases: a systematic review and meta-analysis

Behavioral and Brain Functions
Background Cerebral large artery and small vessel diseases are considered substrates of neurological disorders. We explored how the mechanisms of neurovascular uncoupling, dysfunctional blood–brain-barrier (BBB), compromised glymphatic pathway, and ...
Joseph A. Ackah, Xuelong Li, Huixing Zeng, Xiangyan Chen   +3 more
doaj   +1 more source

Dawson's Fingers in Cerebral Small Vessel Disease [PDF]

Frontiers in Neurology, 2020
To explore Dawson's fingers in cerebral small vessel disease (CSVD) and factors related to the development of Dawson's finger, we collected and analyzed clinical data of 65 patients with CSVD. We found a venous abnormality feature called Dawson's fingers around the ventricles in magnetic resonance images (MRIs) of 20 out of 65 patients with CSVD (30. 8%
Aowei Lv, Zaiqiang Zhang, Ying Fu, Yaping Yan, Li Yang, Wenli Zhu   +5 more
openaire   +3 more sources

Cerebral blood flow autoregulation is impaired in schizophrenia [PDF]

, 2017
Patients with schizophrenia have a higher risk of cardiovascular diseases and higher mortality from them than does the general population; however, the underlying mechanism remains unclear.
al, et, Ku, Hsiao-Lun, Lane, Timothy
core