Results 41 to 50 of about 8,895 (244)
Composition of cerebroside acids as a function of age
The brains of from 11 to 30 rats of various age groups—23 to 418 days old—were pooled and analyzed for total lipids, total cerebrosides, and the individual cerebroside acids.
Yasuo Kishimoto, Norman S. Radin
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An improved procedure for the conversion of cerebroside to ceramide and sphingosine has been devised, consisting of periodate opening of the glycosidic ring, reduction with NaBH4, and hydrolysis under very mild acid conditions to ceramide.
H.E. Carter, J.A. Rothfus, Roy Gigg
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2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A2. [PDF]
Cytosolic phospholipase A2 (GIVA cPLA2) is the only PLA2 that exhibits a marked preference for hydrolysis of arachidonic acid containing phospholipid substrates releasing free arachidonic acid and lysophospholipids and giving rise to the generation of ...
Barbayianni, Efrosini +10 more
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Gray matter, white matter, and myelin were isolated from the frontal lobes of the brains of humans aged 10 months, 6 yr, 9 yr, and 55 yr. The major lipids, including ethanolamine glycerophosphatides (EGP), serine glycerophosphatides (SGP), choline ...
John S. O'Brien, E. Lois Sampson
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Preparation of 6‐ 3 H glucocerebroside [PDF]
Glucocerebroside (1–0‐β‐glucosyl ceramide) can be labeled with 3 H‐borohydride at the 6‐position of the glucose moiety. The 6‐trityl ether of cerebroside is formed first, the remaining hydroxyl groups are acetylated, the trityl group is removed, and the
McMaster, Marvin C., Radin, Norman S.
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Lipid Composition of rat brain myelin in triethyl tin-induced edema
Chronic triethyl tin intoxication was induced in young adult rats by oral feeding of triethyl tin sulfate. Progressively severe brain edema developed during the 3-month experimental period.
YOSHIKATSU ETO +2 more
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Effect of an Inhibitor of Glucosylceramide Synthesis on Cultured Human Keratinocytes [PDF]
Glucosylceramide (GlcCer) is a major glycosphingolipid component of epidermis, which is thought to be related to the barrier function of skin permeability.
Abe, Akira +5 more
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Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action [PDF]
The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable.
Arizza V. +4 more
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Four glycosphingolipids were isolated from rabbit aorta, plasma, and red blood cells. They were identified, by thin-layer chromatography and by quantitative analysis of hexose and fatty acid, as cerebroside, diglycosyl ceramide, triglycosyl ceramide, and
Eric Coles, J. Lindsley Foote
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Human Brain Lipidomics: Investigation of Formalin Fixed Brains
Human brain lipidomics have elucidated structural lipids and lipid signal transduction pathways in neurologic diseases. Such studies have traditionally sourced tissue exclusively from brain bank biorepositories, however, limited inventories signal that ...
Aaron W. Beger +5 more
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