Therapeutics Potential of Cronassial in Experimental Autoimmune Encephalomyelitis: Insights Into Glycosphingolipids and Humoral Immunity. [PDF]
ScientificWorldJournalCurrently, significant attention is being paid to the study of the mechanisms underlying the development of multiple sclerosis (MS), especially factors related to humoral immunity, apoptosis, and sphingolipid metabolism processes. These factors play a key role in neuroinflammation and neurodegeneration during both the acute and chronic stages of the ...
Ghazaryan G +3 more
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Exploring New Frontiers: Alternative Breast Cancer Treatments Through Glycocalyx Research. [PDF]
Breast JBreast cancer (BC) treatment is developing toward more precise and personalized care through the approval of different comprehensive approaches. Clinical practice emphasizes significant patient‐to‐patient variability in treatment response among patients, even those with similar clinical and biological profiles. Recent studies have demonstrated that the
Gorodetska I +5 more
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AAV-Mediated Gene Delivery in Adult GM1-Gangliosidosis Mice Corrects Lysosomal Storage in CNS and Improves Survival [PDF]
, 2010 Background: GM1-gangliosidosis is a glycosphingolipid (GSL) lysosomal storage disease caused by a genetic deficiency of acid β-galactosidase (βgal), which results in the accumulation of GM1-ganglioside and its asialo-form (GA1) primarily in the CNS.
Baek, Rena C. +7 more
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Properties of cerebroside galactosidase [PDF]
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1968 SUMMARY Rat brain cerebrosidase was shown by centrifugal fractionation to be a lysosomal enzyme. The pH optimum was found to be 4.5. Taurocholate greatly stimulated its action. The addition of palmitic acid had little effect on the enzyme activity, but ceramide, sphingosine, and ceramide lactoside inhibited.
Bowen, David M., Radin, Norman S.
openaire +3 more sources
Bright spots in the darkness of cancer: A review of starfishes-derived compounds and their anti-tumor action [PDF]
, 2019 The fight against cancer represents a great challenge for researchers and, for this reason, the search for new promising drugs to improve cancer treatments has become inevitable.
Arizza V. +4 more
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Journal of Lipid Research, 1978 Submicrogram quantities of trimethylsilyl derivatives of cerebrosides obtained from the spleen of a patient with Gaucher's disease and from bovine brain were analyzed by direct probe inlet-chemical ionization mass spectrometry, using isobutane as the ...
T Murata, T Ariga, M Oshima, T Miyatake
doaj +1 more source
A method for fractionation of cerebrosides into classes with different fatty acid compositions
Journal of Lipid Research, 1972 A method is described for the separation of beef brain cerebrosides into three fractions containing different classes of fatty acids: nonhydroxy (I), unsaturated nonhydroxy (II), and hydroxy fatty acid cerebrosides (III).
Aureliu J. Acher, Julian N. Kanfer
doaj +1 more source
Off-resonance magnetisation transfer contrast (MTC) MRI using fast field-cycling (FFC) [PDF]
, 2010 Peer ...
Choi, Chang-Hoon +2 more
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Effect of cerebroside preparations on sterol excretion in the rat*
Journal of Lipid Research, 1960 The addition of cerebroside preparations to synthetic diets fed to rats caused an increased excretion of sterol in the feces as measured by the Liebermann-Burchard reaction.
K.K. Carroll
doaj +1 more source
Preparation and analysis of benzoylated cerebrosides
Journal of Lipid Research, 1973 The benzoylation of cerebrosides with benzoyl chloride and with benzoic anhydride is described, and the derivatives that contained hydroxy and nonhydroxy fatty acids were isolated by high pressure liquid chromatography (HPLC).
Robert H. McCluer, James E. Evans
doaj +1 more source