Results 21 to 30 of about 2,358 (114)

Increased circulating T cell reactivity to GM3 and GQ1b gangliosides in primary progressive multiple sclerosis [PDF]

, 2003
We have previously shown that patients with primary progressive multiple sclerosis (MS) have significantly elevated plasma levels of antibody to GM3 ganglioside compared to patients with relapsing-remitting MS, healthy subjects and patients with other ...
Acarin, Arnon, Baba, Bech, Beraud, Chiba, Endo, Feix, Greer, Greer, Ho, Ilyas, Judith M Greer, Kasai, Kaye D Hooper, Kracun, Kusunoki, Lublin, Markovic-Plese, Martin, Mata, McDonald, Michael F Good, Michael P Pender, Moody, Mullin, Nigel P Wolfe, Offner, Offner, Pamela A McCombe, Pender, Pender, Pender, Peter A Csurhes, Poser, Rees, Sadatipour, Shamshiev, Stevens   +38 more
core   +1 more source

Sphingolipids in Emotional Well‐Being

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Sphingolipids are essential constituents of neuronal membranes and are increasingly recognized as contributors to the key behavioral manifestations associated with emotional well‐being. ABSTRACT Emotional well‐being is a multifactorial concept, which comprises not only life quality of human individuals, but also their mental and physical health.
L. S. Kalinichenko, I. Zoicas, C. Mühle, J. Kornhuber, C. P. Müller   +4 more
wiley   +1 more source

Lannea coromandelica (Houtt.) Merr.: A Comprehensive Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacological Activity

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Nawfal Hasan Siam, Sumaya Akter, Anika Rahman, Taniza Tasnim, Md. Mhamudul Huda Ruhed, Anika Ahmed, Naznin Rahman, Afsana Akter Mim, Tasnim Tabassum, Md. Mazharul Islam Chowdhury, Jakir Ahmed Chowdhury   +10 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]

, 1998
The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, A.
core   +2 more sources

ER stress in antigen‐presenting cells promotes NKT cell activation through endogenous neutral lipids [PDF]

, 2020
CD1d-restricted invariant natural killer T (iNKT) cells constitute a common glycolipid-reactive innate-like T-cell subset with a broad impact on innate and adaptive immunity.
Cheng, Tan‐Yun, Cloots, Eva, De Geest, Bruno, Drennan, Michael, Elewaut, Dirk, Gaublomme, Djoere, Govindarajan, Srinath, Gysens, Fien, Janssens, Sophie, Maelegheer, Margaux, Moody, D Branch, Venken, Koen, Verheugen, Eveline   +12 more
core   +2 more sources

Alternate pathways of cerebroside catabolism [PDF]

Lipids, 1973
AbstractA search was made for new degradative pathways for glucosyl and galactosyl ceramides in an effort to explain the failure of these lipids to accumulate in the brains of children with Krabbe's or Gaucher's disease. Using various buffers and incubation conditions, we tested brain homogenates from 12 day old rats with the stearate‐labeled and ...
Lin, Yuh‐nan, Radin, Norman S.
openaire   +3 more sources

Characterization and Mechanism Prediction of Active Components in Fuganlin Oral Liquid for Respiratory Tract Infections Using UPLC–Q‐TOF–MS and Network Pharmacology

Journal of Analytical Methods in Chemistry, Volume 2026, Issue 1, 2026.
Fuganlin oral liquid (FOL) has been clinically employed for the treatment of pediatric qi deficiency colds, manifesting symptoms such as fever, cough, asthma, and sore throat. However, the chemical composition and bioactive components of FOL have not been clearly elucidated.
Mengyue Zhang, Feng Han, Mingxuan Yang, Zhishan Ye, Ying Cui, Yuefei Wang, Jing Yang, Xin Chai, Rongda Xu   +8 more
wiley   +1 more source

Antimicrobial activities of secondary metabolites of endophytic fungi isolated from Catharanthus roseus [PDF]

, 2017
Introduction: Recently, several endophytes have been shown to possess the potentials to synthesize novel bioactive compounds that have found use for drug discovery. We isolated endophytic fungi associated with Catharanthus roseus collected from the river
Abba, Chika C., Akpotu, Mark O., Esimone, Charles O., Eze, Peter M., Nwachukwu, Charles U., Okoye, Festus B. C., Umeokoli, Blessing O.   +6 more
core   +2 more sources

Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain Development

Journal of Neurochemistry, Volume 169, Issue 10, October 2025.
Ceramides and sphingolipids in brain development and cell compartments. Ceramides and sphingolipids are known to influence multiple steps of brain development, including the formation of the neural tube, neural stem cell polarity and proliferation at the ventricular boundary, neuronal migration—for example, whilst migrating on radial glial processes ...
Kaviya Chinnappa, Fiona Ballorin, Fiona Francis   +2 more
wiley   +1 more source