Quantitation of High-Molecular Proteins in Cerebrospinal Fluid [PDF]
Clinical Chemistry and Laboratory Medicine, 1974 Es werden die technischen Bedingungen beschrieben, die sich fur die Bestimmung des
Schliep, Gisela +2 more
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Dynamics of brain-derived proteins in cerebrospinal fluid [PDF]
Clinica Chimica Acta, 2001 The recent theory of blood-cerebrospinal fluid (CSF) barrier function and dysfunction connects molecular flux and CSF flow rate. A reduced CSF flow rate is sufficient to account for the observed hyperbolic relation between different blood-derived protein concentrations in CSF in cases of a blood-CSF barrier dysfunction.The dynamics of brain-derived ...
Hansotto Reiber
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Cerebrospinal fluid protein biomarkers for Alzheimer’s disease [PDF]
NeuroRX, 2004 The introduction of acetylcholine esterase (AChE) inhibitors as a symptomatic treatment of Alzheimer's disease (AD) has made patients seek medical advice at an earlier stage of the disease. This has highlighted the importance of diagnostic markers for early AD.
Kaj Blennow
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Metabolites, 2022 The different molecular profiles of cerebrospinal fluid (CSF) between ventricular and lumbar compartments remain elusive, especially in the context of leptomeningeal metastasis (LM), which affects CSF flow.
Ji-Woong Kwon +9 more
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Heteromers of amyloid precursor protein in cerebrospinal fluid [PDF]
Molecular Neurodegeneration, 2015 Soluble fragments of the amyloid precursor protein (APP) generated by α- and β-secretases, sAPPα and sAPPβ, have been postulated as promising new cerebrospinal fluid (CSF) biomarkers for the clinical diagnosis of Alzheimer's disease (AD). However, the capacity of these soluble proteins to assemble has not been explored and could be relevant. Our aim is
Cuchillo-Ibáñez, Inmaculada +6 more
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SCO-spondin, a giant matricellular protein that regulates cerebrospinal fluid activity
Fluids and Barriers of the CNS, 2021 Cerebrospinal fluid is a clear fluid that occupies the ventricular and subarachnoid spaces within and around the brain and spinal cord. Cerebrospinal fluid is a dynamic signaling milieu that transports nutrients, waste materials and neuroactive ...
Vania Sepúlveda +4 more
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Sex-Related Differences in Cerebrospinal Fluid Plasma-Derived Proteins of Neurological Patients
Diagnostics, 2021 Background and aims: Cerebrospinal fluid (CSF) protein content presents a sexual dimorphism in humans. We investigated sex-related differences in CSF IgG levels and in the quantification of intrathecal IgG synthesis (IIS). Methods: CSF, serum albumin and
Massimiliano Castellazzi +10 more
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Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid. [PDF]
, 2016 BackgroundClinical diagnosis of parkinsonian syndromes like Parkinson's disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Boman, Andrea +8 more
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Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients. [PDF]
, 2015 Quantification of disease-associated proteins in the cerebrospinal fluid (CSF) has been critical for the study and treatment of several neurodegenerative disorders; however, mutant huntingtin protein (mHTT), the cause of Huntington's disease (HD), is at ...
Andreas Weiss +16 more
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Intrathecal synthesis of complement components C3c and C4 in the central nervous system infections with signs of the acute serous meningitis syndrome [PDF]
Vojnosanitetski Pregled, 2002 Two hundred and ten patients with meningismus and the infections of the central nervous system (CNS) with the clinical symptoms and signs of the acute serous meningitis syndrome, were divided into groups according to etiology (enterovirus meningitis ...
Tatomirović Željka +2 more
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