Results 91 to 100 of about 32,185 (293)

Predicting the Efficacy of Adjuvant Chemotherapy Using Immuno‐Nutritional and Inflammatory Markers in Elderly Patients With Stage III Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine whether immuno‐nutritional and inflammatory markers could serve as predictors of the outcomes of postoperative adjuvant chemotherapy for stage III colorectal cancer in elderly patients. Postoperative lymphocyte‐to‐monocyte ratio and postoperative C‐reactive protein‐to‐albumin ratio accurately predicted the efficacy of ...
Tomoya Tago, Yasuyuki Takamizawa, Takeharu Kato, Hiroshi Nagata, Konosuke Moritani, Shunsuke Tsukamoto, Yukihide Kanemitsu   +6 more
wiley   +1 more source

Lower neurovascular coupling response despite higher cerebral blood flow at rest in apolipoprotein ɛ4 positive adults.

PLoS ONE
Cerebral blood flow at rest declines with age. However, age-related changes in functional measures of cerebrovascular health including cerebrovascular reactivity and neurovascular coupling are not well understood.
Andrew G Pearson, Kathleen B Miller, Adam T Corkery, Nicole A Loggie, Anna J Howery, Leonardo A Rivera-Rivera, Oliver Wieben, Kevin M Johnson, Sterling C Johnson, Jill N Barnes   +9 more
doaj   +1 more source

Early Effects of the Serious Accidents Punishment Act on Occupational Health Outcomes in Korea: A Nationwide Difference‐in‐Differences Study (2017–2023)

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Work‐related injury and occupational disease remain major public health challenges worldwide; South Korea continues to report comparatively high industrial accident rates among OECD countries. To strengthen managerial accountability for worker safety, the Korean government enacted the Serious Accidents Punishment Act (SAPA) in 2021,
Hyewon Park, Misong Woo, Wanhyung Lee
wiley   +1 more source

Behavioral, respiratory and metabolic consequences of impaired cerebrovascular reactivity

, 2020
Carbon dioxide (CO2) and protons (H+) have a strong influence on cerebral perfusion, but the function of this is not clear yet. Here, we found that GPR4, a receptor for H+ in the vasculature, sensed CO2/H+ and that an endothelial Gαq/11-dependent ...
Wagner, Carsten A, Assmann, Julian C, MüllerFielitz, Helge, Ludewig, Peter, Wenzel, Jan, Lembrich, Beate, Bettoni, Carla, Brands, Josefine, Raasch, Walter, König, Gabriele M, Kostenis, Evi, Natsagdorj, Rentsenkhand, Schmidt, Kjestine, Fiehler, Jens, Sedlacik, Jan, Stölting, Ines, Wegmann, Michael, deWit, Cor, Offermanns, Stefan, Wlather, Thomas, Gass, Peter, Richter, Marius, Vogt, Miriam A, Huber, Gianna, Schwaninger, Markus   +24 more
core  

Transcranial Doppler ultrasound to assess cerebrovascular reactivity: reliability, reproducibility and effect of posture [PDF]

, 2013
Transcranial Doppler ultrasound (TCD) allows measurement of blood flow velocities in the intracranial vessels, and can be used to assess cerebral vasodilator responses to a hypercapnic stimulus. The reliability of this technique has not been established,
Mark A. Cutting, Jonathan D. Buckley, McDonnell, Michelle N., Michelle N. McDonnell, Berry, N., Peter R.C. Howe, Buckley, J., Keage, Hannah A., Hannah A. Keage, Howe, Peter R. C., Buckley, Jonathan D., Keage, H., McDonnell, M., Howe, P., Cutting, Mark A., Narelle M. Berry, Cutting, M., Berry, Narelle M.   +17 more
core   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Effects of sevoflurane versus propofol on cerebrovascular reactivity to carbon dioxide during laparoscopic surgery

, 2017
Chunyi Wang,1,* Cheng Ni,1,* Gang Li,1 Yan Li,1 Liyuan Tao,2 Nan Li,2 Jun Wang,1 Xiangyang Guo1 1Department of Anesthesiology, 2Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China *These authors contributed ...
Li G, Li Y, Tao L, Wang C, Guo X, Ni C, Wang J, Li N   +7 more
core  

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

Annals of Neurology, EarlyView.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones, Blessing Nyakutsikwa, Michael H. Askenase, Matthew Gittins, Mary Newland, Siobhan Crilly, Paul R. Kasher, Yvonne Davidson, Federico Roncaroli, Stuart M. Allan, Lauren H. Sansing, Wendy Ziai, Daniel F. Hanley, INFLAME‐ICH Investigators, Mark Harrigan, David Miller, Judy Huang, Wendy Ziai, Jack Jallo, Fred Rincon, Gaurav Gupta, Igor Rybinnik, Diederik Bulters, Mary Leigh Gelea, Andras Buki, Erzsebet Ezer, Hiren Patel, Adrian Parry‐Jones, Charles Matouk, Kevin Sheth / Lauren Sansing, Ali Zomorodi, Michael James, Pal Barzo, Krisztian Tanczos, Gregory Thompson, Ventatakrishna Rajajee/Aditya Pandey, Peter Nakaji, Shawn E. Wright, Walter Galicich, Thomas Bergman, Andrew Carlson, Huy Tran, Philipp Taussky, Safdar Ansari, Fuat Arikan, Marcelino Baguena, Ronald Reimer, W. David Freeman, Ania Pollack, John Terry, Geza Mezey, Katalin Szabo/Laszlo Csiba, Robert F. James, Steven J. Barrer, Larami MacKenzie   +54 more
wiley   +1 more source

Advances in Chitosan Nanoparticles: A Comprehensive Review of Properties, Synthesis, Characterization, Multidisciplinary Applications, and Future Perspectives

Journal of Applied Polymer Science, EarlyView.
This review highlights the synthesis of chitosan nanoparticles from natural sources, the thorough characterization of them, and use of microscopic and spectroscopic methods. It emphasizes that it has some indispensable properties such as being non‐toxic, antimicrobial, and capable of controlled drug release.
Mariam Sohail Mansoor, Nayab Raza, Furqana Bibi, Madiha Mumtaz, Asif Abbas, Farasat Haider, Basit Ali   +6 more
wiley   +1 more source

Acute hyperglycemia reduces cerebrovascular reactivity: The role of glycemic variability

, 2014
Cerebral vasomotor reactivity (CVR) is reduced in patients with diabetes mellitus (DM), and glucose variability (GV) might be responsible for cerebrovascular ...
Donno, S, Palazzo, P, Lauro, D, Altavilla, R, Di Flaviani, A, Giordani, I, Picconi, F, Pasqualetti, P, FRONTONI, SIMONA, Vernieri, F, LAURO, DAVIDE, Ylli, D, Malandrucco, I, Frontoni, S, Passarelli, F   +14 more
core   +1 more source