Results 21 to 30 of about 28,548 (239)

Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis

Intensive Care Medicine Experimental, 2023
Background Although vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the full impact such agents have on cerebrovascular reactivity remains unclear.
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izabella Marquez, Fiorella Amenta, Kevin Y. Stein, Frederick A. Zeiler   +7 more
doaj   +1 more source

Impaired Cerebrovascular Reactivity in Multiple Sclerosis [PDF]

JAMA Neurology, 2014
Cerebrovascular reactivity (CVR) is an inherent indicator of the dilatory capacity of cerebral arterioles for a vasomotor stimulus for maintaining a spontaneous and instant increase of cerebral blood flow (CBF) in response to neural activation. The integrity of this mechanism is essential to preserving healthy neurovascular coupling; however, to our ...
Olga, Marshall, Hanzhang, Lu, Jean-Christophe, Brisset, Feng, Xu, Peiying, Liu, Joseph, Herbert, Robert I, Grossman, Yulin, Ge   +7 more
openaire   +2 more sources

The impact of sedative and vasopressor agents on cerebrovascular reactivity in severe traumatic brain injury

Intensive Care Medicine Experimental, 2023
Background The aim of this study is to evaluate the impact of commonly administered sedatives (Propofol, Alfentanil, Fentanyl, and Midazolam) and vasopressor (Dobutamine, Ephedrine, Noradrenaline and Vasopressin) agents on cerebrovascular reactivity in ...
Logan Froese, Emma Hammarlund, Cecilia A. I. Åkerlund, Jonathan Tjerkaski, Erik Hong, Caroline Lindblad, David W. Nelson, Eric P. Thelin, Frederick A. Zeiler   +8 more
doaj   +1 more source

Breath holding for 20 s following extended expiration is a practical, effective and robust standard when measuring cerebrovascular reactivity in healthy adults using BOLD fMRI at 3 T

NeuroImage: Reports, 2021
Background and Purpose: BOLD fMRI is becoming the preferred modality to study cerebrovascular reactivity. Amongst the vasoactive stimuli to induce it, breath holding is considered equal to other methods but both cerebrovascular reserve measures and ...
Jörg Larsen, Kai Kallenberg, Johanna Rühlmann, Jürgen Baudewig, Eike A. Nickel, Michael Knauth, Peter Dechent   +6 more
doaj   +1 more source

Breath holding index in episodic primary headaches [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Examination of cerebrovascular reactivity in patients with primary headaches is focused mainly on migraine, while the smaller number of studies deals with tensiontype and cluster headache, or comparison of cerebral haemodynamic in ...
Podgorac Ana, Petrušić Igor, Radojičić Aleksandra, Zidverc-Trajković Jasna   +3 more
doaj   +1 more source

Comparison of cerebrovascular reactivity tests: a pilot human study

Journal of Electrical Bioimpedance, 2017
In neurosurgery intensive care units, cerebrovascular reactivity tests for neuromonitoring are used to evaluate the status of cerebral blood flow autoregulation; lack of autoregulation indicates a poor patient outcome.
Bodo Michael, Mahon Richard, Razumovsky Alex, Kouperberg Efim, Crimmins Michael, Armonda Rocco, Baruch Martin   +6 more
doaj   +1 more source

Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care?

Intensive Care Medicine Experimental, 2022
Background Impaired cerebral autoregulation has been linked with worse outcomes, with literature suggesting that current therapy guidelines fail to significantly impact cerebrovascular reactivity.
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Carleen Batson, Trevor Slack, Kevin Y. Stein, Francois Mathieu, Frederick A. Zeiler   +7 more
doaj   +1 more source

Cerebrovascular reactivity mapping without gas challenges [PDF]

NeuroImage, 2017
Cerebrovascular reactivity (CVR), the ability of cerebral vessels to dilate or constrict, has been shown to provide valuable information in the diagnosis and treatment evaluation of patients with various cerebrovascular conditions. CVR mapping is typically performed using hypercapnic gas inhalation as a vasoactive challenge while collecting BOLD images,
Peiying, Liu, Yang, Li, Marco, Pinho, Denise C, Park, Babu G, Welch, Hanzhang, Lu   +5 more
openaire   +2 more sources

Cerebrovascular pressure reactivity and brain tissue oxygen monitoring provide complementary information regarding the lower and upper limits of cerebral blood flow control in traumatic brain injury: a CAnadian High Resolution-TBI (CAHR-TBI) cohort study

Intensive Care Medicine Experimental, 2022
Background Brain tissue oxygen tension (PbtO2) and cerebrovascular pressure reactivity monitoring have emerged as potential modalities to individualize care in moderate and severe traumatic brain injury (TBI).
Alwyn Gomez, Mypinder Sekhon, Donald Griesdale, Logan Froese, Eleen Yang, Eric P. Thelin, Rahul Raj, Marcel Aries, Clare Gallagher, Francis Bernard, Andreas H. Kramer, Frederick A. Zeiler   +11 more
doaj   +1 more source

Effect of Smoking on Cerebrovascular Reactivity [PDF]

Journal of Cerebral Blood Flow & Metabolism, 1996
Current smoking is a risk factor for stroke. The aim of this study was to evaluate the effect of smoking one cigarette on cerebral hemodynamics. Using transcranial Doppler ultrasound, we studied the changes of flow velocity after hypercapnia in the middle cerebral arteries (MCAs) of 24 healthy young smokers and 24 healthy controls matched for age and ...
M, Silvestrini, E, Troisi, M, Matteis, L M, Cupini, G, Bernardi   +4 more
openaire   +2 more sources