Results 1 to 10 of about 36,381 (254)

Serum Ceruloplasmin Level as a Predictor for the Progression of Diabetic Nephropathy in Korean Men with Type 2 Diabetes Mellitus [PDF]

Diabetes & Metabolism Journal, 2015
BackgroundOxidative stress is known to be associated with progression of diabetic kidney disease. Ceruloplasmin acts as a pro-oxidant under conditions of severe oxidative stress.
Min Jung Lee, Chang Hee Jung, Yu Mi Kang, Jung Eun Jang, Jaechan Leem, Joong-Yeol Park, Woo Je Lee   +6 more
doaj   +2 more sources

Association of serum trace elements with non-invasive fibrosis scores in metabolic dysfunction-associated steatotic liver disease. [PDF]

Sci Rep
Liver biopsy is not a routine screening tool for detecting fibrosis progression in metabolic dysfunction-associated steatotic liver disease (MASLD). Noninvasive methods based on serum biomarkers are used instead.
Banisefid E, Zonouzi SK, Hamzehzadeh S, Nikniaz Z, Moghaddamziabari S, Alizadeh L.   +5 more
europepmc   +2 more sources

Serum copper and ceruloplasmin levels as biomarkers reflecting liver fibrosis in children with autoimmune hepatitis. [PDF]

Clin Exp Pediatr
Background Clinical, biochemical, histological, and immunological indicators are frequently used to diagnose autoimmune hepatitis (AIH), a chronic inflammatory liver disease affecting children.
Nagi SAM, Elashmawy MI, Elashkar AE, Hafez MZ, Emara AAE, Abdelhay OM, Fouda AAB, Doma MA, Awad AM, Saba AM, Ahmed HA, Allah AMG, Abdelraheem FM, Gad MA, Soliman MA, Abdalrhman TI, Awad KH, El-Lebedy IAKM, Abdelnaser MM, Kareem MZA, Hassan MF, Khalifa SSM.   +21 more
europepmc   +2 more sources

Evaluation of salivary ceruloplasmin for the diagnosis of Wilson's disease. [PDF]

Sci Rep
The serum ceruloplasmin assay is the most commonly used test for diagnosing Wilson’s disease (WD). Despite the utility of non-invasive tests for diagnosing WD, no such tests have been developed.
Zhang N, Wu L, Jiang P, Ji Z, Yin M, Zhou H, He L, Xia Z, Wang F, Xiao X, Han H.   +10 more
europepmc   +2 more sources

Impact of Parenteral Copper and Zinc Administration on Reproduction, Inflammation, and Antioxidant Responses of <i>Bos indicus</i> Beef Heifers. [PDF]

Animals (Basel)
Two experiments evaluated the effects of copper (Cu) and zinc (Zn) injection on body weight (BW), body condition score (BCS), pregnancy rate, ovarian traits, and antioxidant and inflammatory responses of beef heifers. In Exp.
Silva LGD, Vedovatto M, Ranches J, Martins EC, Ferreira MF, Lima EA, Ferreira LCL, Reis WVAD, Franco GL.   +8 more
europepmc   +2 more sources

TDMQ20 as A Drug Candidate for Wilson's Disease: Comparison with D-Penicillamine, Trientine, and Tetrathiomolybdate In Vitro and In Mice. [PDF]

Pharmaceutics
Background/Objectives: The lifelong treatment of Wilson’s disease (WD) currently relies on copper chelators with relatively poor metal specificity, which frequently exhibit serious adverse effects.
Zhu Y, Peng W, Liu G, Li L, Zhou Z, Nguyen M, Robert A, Liu Y, Meunier B.   +8 more
europepmc   +2 more sources

Assessing whether serum ceruloplasmin promotes non-alcoholic steatohepatitis via regulating iron metabolism [PDF]

Journal of Medical Biochemistry, 2023
Background: Non-alcoholic steatohepatitis (NASH) is a progressive form of non-alcoholic fatty liver disease (NAFLD). The diagnostic gold standard for detecting NASH still relies upon an invasive pathological biopsy.
Xia Ziqiang, Hu Mei, Zheng Liang, Zheng Endian, Deng Min, Wu Jinming, Sheng Xiong   +6 more
doaj   +1 more source

Assessment of the diagnostic value of serum ceruloplasmin for Wilson’s disease in children

BMC Gastroenterology, 2022
Background Serum ceruloplasmin is one of the major diagnostic parameters for Wilson’s disease (WD). Age and gender difference of serum ceruloplasmin remain controversy.
Xinshuo Lu, Simin Li, Wen Zhang, Yunting Lin, Zhikun Lu, Yanna Cai, Xueying Su, Yongxian Shao, Zongcai Liu, Huiying Sheng, Yonglan Huang, Li Liu, Chunhua Zeng   +12 more
doaj   +1 more source

Role of serum ceruloplasmin in the diagnosis of Wilson's disease: A large Chinese study

Frontiers in Neurology, 2022
BackgroundConventionally, serum ceruloplasmin levels below the lower reference limit (0. 20 g/L) is considered a diagnostic cutoff point for Wilson's disease (WD).
Yue Yang, Wenjie Hao, Taohua Wei, LuLu Tang, Nannan Qian, Yulong Yang, Hu Xi, Shijie Zhang, Wenming Yang, Wenming Yang   +9 more
doaj   +1 more source

DISTINCT PHENOTYPE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH LOW LEVELS OF FREE COPPER AND OF CERULOPLASMIN [PDF]

Arquivos de Gastroenterologia, 2020
BACKGROUND: Copper deficiency has been linked to alterations in lipid metabolism and hepatic steatosis. Oxidative stress plays a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD).
Vinicius S NUNES, Adriana R ANDRADE, Ana L V GUEDES, Marcio A DINIZ, Claudia P OLIVEIRA, Eduardo L R CANÇADO   +5 more
doaj   +1 more source