Results 41 to 50 of about 39,559 (211)

Missense Variants in the A Isoform of FGF13 as a Novel Cause of Paroxysmal Dyskinesia

Movement Disorders, EarlyView.
Abstract Background Pathogenic variants within the unique N‐terminal inactivation particle of FGF13 isoform A (FGF13A) have so far been associated only with an X‐linked dominant epileptic encephalopathy (DEE). Objective The aim was to expand the clinical and molecular spectrum of FGF13A‐related disorder.
Cyril Mignot, Matthildi Athina Papathanasiou Terzi, Claudia Ravelli, Elisabeth Bosch, Xueqin Lin, Adeline Trauffler, Roseline Caumes, Andrew E. Fry, Clementine Fort, Gaelle Gauthe, Regina Trollmann, Thomas Wirth, Mathieu Anheim, Aurélie Méneret, Emmanuel Roze, Jean‐Madeleine de Sainte Agathe, Hailan He, Eleni Panagiotakaki, Gaëtan Lesca, André Reis, Diane Doummar, Thomas Smol, Georgia Vasileiou   +22 more
wiley   +1 more source

Revisiting the Association Between Calcium Channel Blockers and Parkinson's Disease in the E3N Cohort

Movement Disorders, EarlyView.
Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard, Agnès Fournier, Émeline Courtois, Fanny Artaud, Pascale Tubert‐Bitter, Emmanuel Roze, Ismaïl Ahmed, Anne C.M. Thiébaut, Alexis Elbaz, Thi Thu Ha Nguyen   +9 more
wiley   +1 more source

Awareness of cognitive decline trajectories in asymptomatic individuals at risk for AD

Alzheimer’s Research & Therapy, 2020
Background Lack of awareness of cognitive decline (ACD) is common in late-stage Alzheimer’s disease (AD). Recent studies showed that ACD can also be reduced in the early stages.
Federica Cacciamani, Luisa Sambati, Marion Houot, Marie-Odile Habert, Bruno Dubois, Stéphane Epelbaum, on behalf of the INSIGHT-PreAD study group   +6 more
doaj   +1 more source

Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements

Movement Disorders, EarlyView.
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano, Cécile Galléa, Asya Ekmen, Cécile Delorme, Eavan M. McGovern, Quentin Salardaine, Lina Daghsen, Manon Gomes, Vanessa Brochard, Eoin Mulroy, Kailash P. Bhatia, Carlo Fusco, Miryam Carecchio, Norbert Brüggemann, Alexander Münchau, Victoria Gonzalez, Diane Doummar, Christine Tranchant, Mathieu Anheim, Philippe Damier, Florence Riant, Mohamed Doulazmi, Agathe Roubertie, Caroline Dubacq, Oriane Trouillard, Romain Valabregue, Mélanie Didier, Benoit Beranger, Pierre Pouget, Marie Vidailhet, Sabine Meunier, Aurélie Méneret, Yulia Worbe, Emmanuel Roze   +33 more
wiley   +1 more source

Oméga 3 et neurotransmission cérébrale

Oléagineux, Corps gras, Lipides, 2004
Les acides gras polyinsaturés (AGPI) sont des constituants structuraux fondamentaux du système nerveux central (SNC) dont la teneur conditionne le fonctionnement des cellules neuronales. Ils sont des acteurs de la communication intercellulaire, notamment
Vancassel Sylvie
doaj   +1 more source

Le cerveau face à Dieu (épisode 172)

, 2021
Le contact avec Dieu pourrait se voir dans le cerveau. La méthode scientifique n’est peut-être pas parfaite, mais il semble que cela soit la meilleure approche que l’humanité ait trouvée pour comprendre le fonctionnement du vivant et du monde au sens ...
Christophe Rodo
core  

Psychosocial Determinants of Pain in Muscle Biopsy

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Open muscle biopsy (OMB) is a key diagnostic tool for neuromuscular diseases, though patients often worry about risks and discomfort. This study aimed to assess pain during and after OMB, factors influencing pain perception, and adverse events.
Beatrice Labella, Emmanuelle Lacene, Maud Beuvin, Anaïs Chanut, Angeline Madelaine, Favienne Levy‐Borsato, Guy Brochier, Clémence Labasse, Guillaume Bassez, Danielle Seilhean, Sarah Leonard‐Louis, Teresinha Evangelista   +11 more
wiley   +1 more source

L'Elagage synaptique

Cortica
Hebb (1949) a proposé que la force synaptique entre deux neurones augmente avec l'activité simultanée et que les connexions neuronales persistent si elles sont utilisées.
Cherine Fahim Fahmy
doaj   +1 more source

Kyste hydatique cérébral chez l'enfant: à propos de 5 cas

The Pan African Medical Journal, 2014
Le kyste hydatique cervical est une pathologie rare, mais non exceptionnel chez l'enfant. Nous rapportons rétrospectivement une série de cinq cas de kyste hydatique cérébral opérés, avec une revue de la littérature.
Mohamed Belahcen, Khalid Khattala, Aziz Elmadi, Youssef Bouabdellah   +3 more
doaj   +1 more source

‘Everything is a signal’: speaking circuits and noisy signs in the making of language‐oriented AI « Tout est signal » : circuits parlants et signes bruyants dans la création de l'IA orientée langage

Journal of the Royal Anthropological Institute, EarlyView.
Contemporary artificial intelligence (AI) technologies are often presumed to be capable of revealing unmediated truths about the world, including the truths language might hold, echoing the long‐standing assertion that language's primary function is to directly translate reality.
Beth M. Semel
wiley   +1 more source