Results 211 to 220 of about 23,420 (253)
Some of the next articles are maybe not open access.
Journal of Genetic Counseling, 2019
AbstractPrenatal cell‐free DNA screening (cfDNA) provides more genetic risk information about the fetus than has ever been possible. At the same time, the rapid expansion of new cfDNA panels raises important questions about how to structure patient‐centered discussions that best support patients' decision‐making about its use. To address this question,
Ruth M, Farrell +4 more
openaire +2 more sources
AbstractPrenatal cell‐free DNA screening (cfDNA) provides more genetic risk information about the fetus than has ever been possible. At the same time, the rapid expansion of new cfDNA panels raises important questions about how to structure patient‐centered discussions that best support patients' decision‐making about its use. To address this question,
Ruth M, Farrell +4 more
openaire +2 more sources
Association of cfDNA levels and bothrops envenomation
Toxicon, 2021In the Amazon, around 90% of snakebites are caused by the Bothrops genus. Complications arising from Bothrops envenomations result from the inflammatory and coagulotoxic activities of the venom. The aim of this study was to investigate the potential of cell-free DNA (cfDNA) as a biomarker of severity in Bothrops snakebites. Patients were treated at the
Êndila, de Souza Barbosa +10 more
openaire +2 more sources
Journal of Physics: Condensed Matter, 2022
Abstract In this study, a comprehensive numerical simulation was done to investigate the electrokinetic translocation of cfDNA molecule as well as the possibility of its detection and separation in insulator based dielectrophoresis (iDEP) systems.
Azita Abdollahi, Hossein Shokouhmand
openaire +2 more sources
Abstract In this study, a comprehensive numerical simulation was done to investigate the electrokinetic translocation of cfDNA molecule as well as the possibility of its detection and separation in insulator based dielectrophoresis (iDEP) systems.
Azita Abdollahi, Hossein Shokouhmand
openaire +2 more sources
cfDNA detection for HPV+ squamous cell carcinomas
Oral Oncology, 2021High-risk human papillomavirus (HPV) is an etiologic factor in a spectrum of squamous cell carcinomas including anal, cervical, and oropharyngeal. HPV cell free DNA (cfDNA) is shed from the primary tumor into systemic circulation and can be detected using several platforms including quantitative PCR, digital droplet PCR, or next generation sequencing ...
Kate, Chatfield-Reed +2 more
openaire +2 more sources
Closing in on cfDNA-based detection and diagnosis
Nature Reviews Cancer, 2020Two papers in Nature Medicine report studies that validate the utility of cell-free methylated DNA analysis for early detection of renal cell carcinomas and diagnosis of central nervous system tumours.
openaire +2 more sources
Assessing HER2 Amplification in Plasma cfDNA
2018Digital PCR (dPCR) is a highly accurate method to determine DNA concentration. In dPCR, DNA is portioned into many discrete single entities, and these are analyzed individually for the presence or absence of a target molecule of interest. Here we describe how digital PCR can be employed to determine the presence of oncogenic amplification through ...
Garcia-Murillas, I, Turner, NC
openaire +3 more sources
From cfDNA to Sequencing: Workflows and Potentials
2018Cell-free DNA (cfDNA) is acquiring increasingly importance in oncologic clinical practice, mostly due to its role in predicting the onset of therapy resistance by following the mutation status changes of patients. In this field, high-sensitivity methods like next-generation sequencing (NGS) could help to accurately detect somatic mutations at low ...
Michela, Tebaldi, Samanta, Salvi
openaire +2 more sources
The samples contain genomic sequencing data of cfDNA from healthy individuals and those with kidney disease.
openaire +1 more source
openaire +1 more source
, 2017 Since the discovery of cfDNA (cell-free DNA), many of its applications in molecular medicine have been considered and researched: from diagnosing and monitoring tumors, and predicting disease outcome using specific biomarkers, to the detection and prediction of aberrant fetus development using noninvasive prenatal diagnostics.
openaire