Results 221 to 230 of about 29,683 (253)

Molekulární mechanismy účinků cfDNA

2023
The biological role of free circulating DNA is currently being investigated mainly in terms of the etiology of autoimmune conditions and cancer. It appears that the role of cfDNA of nuclear or mitochondrial origin in interacting with receptors of the innate immune system is quite complex and cfDNA is thus involved in a variety of molecular mechanisms ...
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lung cancer cfDNA

whole genome sequencing of lung cancer ...
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Baseline cfDNA characteristics and evolution of cfDNA profile during treatment with selective FGFR inhibitor TAS-120.

Journal of Clinical Oncology, 2019
3056 Background: There is an increasing role for cfDNA in monitoring response and mechanisms of resistance. We performed cfDNA analysis in a subset of patients enrolled on a Phase I trial with an irreversible, selective FGFR1-4 inhibitor, TAS-120.
Tyler J. Moss, Jordi Rodon Ahnert, Holly D. Oakley, Michael Kahle, Daniel D. Karp, Shubham Pant, Jeena Jacob, Victoria M. Raymond, Richard B. Lanman, Lawrence Kwong, Mark Routbort, Nital Soni, Jerry Huang, Milind M. Javle, Funda Meric-Bernstam   +14 more
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cfDNA-Test auch bei Zwillingsschwangerschaft verlässlich

gynäkologie + geburtshilfe, 2019
In allen Diskussionen uber die moralischen Aspekte der nichtinvasiven Pranataldiagnostik wird zumindest eines nicht angezweifelt: die Akkuratesse der Tests auf zellfreie DNA (cfDNA) bei Trisomie 21. Auch wenn Zwillinge unterwegs sind, trifft dies zu.
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Short cfDNA fragments

The development of minimally-invasive diagnostic tools is crucial for improving outcomes and managing complex diseases such as cancer or sepsis. Cell-free DNA (cfDNA), fragments of DNA circulating in body fluids, holds promise as a basis for such diagnostic tools.
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Closing in on cfDNA-based detection and diagnosis

Nature Reviews Cancer, 2020
Two papers in Nature Medicine report studies that validate the utility of cell-free methylated DNA analysis for early detection of renal cell carcinomas and diagnosis of central nervous system tumours.
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cfDNA fragmentomics for preeclampsia prediction

To investigate whether cfDNA fragmentomic features have the potential to predict early-onset or late-onset PE, we performed WGS of plasma cfDNA (>10X final read depth) from pregnant women with PE (n=109 for early-onset PE, n=333 for late-onset PE) and sampling-gestation-matched healthy controls (n=476).
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Gestational Diabetes mellitus cfDNA Research

The cfDNA analysis of 299 nested case control pairs recruited in Tianjin during three pregnancies was conducted to explore the dynamic change pattern of pregnant women with gestational diabetes mellitus.
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Using cfDNA and ctDNA as Oncologic Markers: A Path to Clinical Validation

International Journal of Molecular Sciences, 2023
Baskaran Subramani
exaly  

cfDNA methylation analysis detects RCC

Nature Reviews Urology, 2020
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