Results 211 to 220 of about 42,468 (308)

Mitochondrial DNA release via VDAC1 in keratinocytes: a key driver of innate immunity and vitiligo pathogenesis. [PDF]

Cell Death Dis
Lv J, Xu W, Jiang P, Yu W, Xue H, Hu N, Cao Y, Zhang H, Yin C, Gao R.   +9 more
europepmc   +1 more source

CGA General Half [PDF]

IEEE Annals of the History of Computing, 2019
openaire   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Interferon stimulatory DNA activates the DNA damage signaling through ATM and DNA-PK sensing. [PDF]

J Biol Chem
Kemiha S, Rejón-Franco L, Ghibaudo E, Eloiflin RJ, Chemarin M, Hawillo K, Laguette N, Técher H.   +7 more
europepmc   +1 more source

Advances of cGAS

Advances in Marine Sciences, 2017
openaire   +1 more source

‘CLOSING THE CARBON LOOP’: Climate Policy Discourses and the Material Politics of Municipal Waste‐to‐Biofuel Programs

International Journal of Urban and Regional Research, EarlyView.
Abstract Waste‐to‐biofuel (WTB) programs have gained popularity as a municipal circular economy and an emissions reduction strategy. The upgrading of biofuels to renewable natural gas (RNG) has drawn particular interest, as RNG can displace conventional fossil fuels in any existing natural gas end use and be delivered through existing pipeline ...
Taylor Davey
wiley   +1 more source

Degradable STING nanomodulators orchestrate the innate-to-adaptive immune response for NIR-II photothermal-immunotherapy via a cancer-immunity cycle. [PDF]

Mater Today Bio
Wei Q, Zhu Z, Li Y, Sun S, Gao G, Wan Y, Hao Y, Lei J, Xu J, Hu Q, Zheng W, Guo Y, Shen JW.   +12 more
europepmc   +1 more source

Cenozoic Tectonics Ignite Mitochondrial Codon Innovations Propelling Canid Body Size Evolution and Transcontinental Radiations

Integrative Zoology, EarlyView.
We decode mitochondrial genomes across all extant canids, revealing lineage‐specific codon optimization driven by altitude, predation, and body size. A tripartite framework integrates geological events, metabolic constraints, and adaptive radiation to explain carnivore evolution.
Xiaoyang Wu, Xibao Wang, Yongquan Shang, Yao Chen, Haotian Cai, Tian Xia, Qinguo Wei, Weilai Sha, Honghai Zhang   +8 more
wiley   +1 more source

Bridging innate immunity and iron-dependent death: the interplay between cyclic GMP-AMP synthase-stimulator of interferon genes nexus and ferroptosis in cancer and inflammation. [PDF]

Front Cell Dev Biol
Chen XX, Hou YQ, Chen XX, Zhou Q, Wang X.   +4 more
europepmc   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source