Results 301 to 310 of about 45,269 (354)

Beyond tumour suppression: cGAS-STING pathway in urologic malignancies: Context-dependent duality and therapeutic implications. [PDF]

Clin Transl Med
Wei Q, Zhao K, Wu Y, Wu W, Hao N.
europepmc   +1 more source

Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast

Australian Endodontic Journal, EarlyView.
ABSTRACT Etidronic acid (HEBP) causes fewer alterations in dentine and can be used mixed with sodium hypochlorite during root canal preparation. This study investigated the cytotoxicity effects of the HEDP and EDTA on human periodontal ligament fibroblast cells. Primary culture was established from human periodontal ligament tissue of one donor and was
Bruno Vila Nova de Almeida, Patrícia de Almeida Rodrigues, Geovanni Pereira Mitre, Maria Sueli da Silva Kataoka, João de Jesus Viana Pinheiro, Talita Tartari, Oscar Faciola Pessoa   +6 more
wiley   +1 more source

β-Hydroxybutyrate Acts as an Exercise Mimetic to Protect the Aging Liver. [PDF]

Aging Cell
Li K, Wang L, Zhu D, Wang W, Guo Y, Gao H, Zhou M, Xiao W.   +7 more
europepmc   +1 more source

A model for de novo pigmentation of amelanotic retinal pigment epithelial cells

Acta Ophthalmologica, EarlyView.
Abstract Purpose Retinal Pigment Epithelial (RPE) cells perform critical functions in the visual cycle. Their melanin pigmentation, which is organized into specialized compartments – melanosomes, is highly critical for proper vision. A chemical method to induce pigmentation in a non‐pigmented model of ARPE‐19 cells was applied using L‐DOPA as a ...
Santosh Gupta, Lyubomyr Lytvynchuk, Taras Ardan, Hana Studenovska, Georgina Faura, Lars Eide, Ljubo Znaor, Slaven Erceg, Knut Stieger, Jan Motlik, Goran Petrovski   +10 more
wiley   +1 more source

Alpha-herpesvirus US1 interacts with cGAS to suppress type I IFN responses and antiviral defense. [PDF]

PLoS Pathog
Qu W, Yuan Y, Shen D, Zhang J, Huang X, Wu L, Yin H, Zhao Z, Wang H, Chai L, Wu J, He X, Zhu C, Zhao D, Li X.   +14 more
europepmc   +1 more source

Bridging innate and adaptive tumor immunity: cGAS-STING pathway activation to potentiate immune checkpoint blockade. [PDF]

J Exp Clin Cancer Res
Li Z, Zheng W, Liu Y, Cao R, Wei J, Jia H.   +5 more
europepmc   +1 more source

Excessive Kynurenine Metabolism Impairs Lysosomal acidification and Triggers mtDNA Release via the AHR/CISH/ATP6V1A Axis in Decidual Macrophages Associated with Unexplained Recurrent Pregnancy Loss. [PDF]

Int J Biol Sci
Song G, Li H, Zhang M, Li Y, Tao X, Wang A, Wang J, Novakovic B, Cannon RD, Saffery R, Qi H, Zhang H, Zhou X.   +12 more
europepmc   +1 more source

STING agonists as antiviral agents. [PDF]

FEBS Lett
Nelson TS, Ma Z.
europepmc   +1 more source

RNF185 promotes esophageal squamous cell carcinoma progression by regulating BAK1 ubiquitination and activating the cGAS-STING-IRF3 pathway. [PDF]

Eur J Med Res
Wang KH, Zhu H, Xu MD, Wang YP, Fan QQ, Cen DP, Wang SJ.   +6 more
europepmc   +1 more source