Results 101 to 110 of about 50,213 (312)
The Journal of Headache and Pain, 2019 Background Monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its receptor are efficacious for the prevention of migraine headaches.
Raffi Manoukian +5 more
doaj +1 more source
Comorbidity Patterns Between Hearing Loss and Symptomatic Dizziness in Middle‐Aged and Older Adults
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective To explore the comorbidity patterns between hearing loss and symptomatic dizziness (HL‐SD) in middle‐aged and older adults. Methods This cross‐sectional study used data from the 1999 to 2004 National Health and Nutrition Examination Survey (NHANES). After excluding incomplete data, 2961 participants aged 40–69 were analyzed. Logistic
Chun‐Yan Liu +6 more
wiley +1 more source
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
Allergy, EarlyView.ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source
Infection control in the brain and the eye
Acta Ophthalmologica, EarlyView.Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Female mice exhibit a more sensitive automated squint response to pain induced by CGRP and amylin [PDF]
, 2021 Brandon J. Rea +7 more
openalex +1 more source
The Journal of Headache and Pain, 2019 Background Monoclonal antibodies (mAbs) towards CGRP or the CGRP receptor show good prophylactic antimigraine efficacy. However, their site of action is still elusive.
Jacob C. A. Edvinsson +6 more
doaj +1 more source
Acta Ophthalmologica, EarlyView.Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry +27 more
wiley +1 more source
Comparison of CGRP and NO Responses in the Human Peripheral Microcirculation of Migraine and Control Subjects [PDF]
, 2008 M-L Edvinsson, Lars Edvinsson
openalex +1 more source
The Calcitonin/Calcitonin Gene-Related Peptide Family in Invertebrate Deuterostomes
Frontiers in Endocrinology, 2018 Calcitonin (CT)/CT gene-related peptide (CGRP) family peptides (CT/CGRP family peptides) including CT, CGRP, adrenomedullin, amylin, and CT receptor-stimulating peptide have been identified from various vertebrates and perform a variety of important ...
Toshio Sekiguchi
doaj +1 more source
TrkA abundance is increased in cutaneous nerves in bortezomib‐induced neuropathy
Brain Pathology, EarlyView.Cutaneous nerves in bortezomib‐induced peripheral neuropathy (BIPN) show reduced nerve fiber density, increased TrkA expression, and enhanced dermal angiogenesis, highlighting a pathological switch in NGF/TrkA signaling that may contribute to nerve damage and pain. Abstract Tropomyosin receptor kinase A (TrkA), a high‐affinity receptor for nerve growth
Yuying Jin +14 more
wiley +1 more source