Results 101 to 110 of about 43,468 (306)
The Role of Asiatic Acid in Preventing Dental Pulp Inflammation: An in-vivo Study
Clinical, Cosmetic and Investigational Dentistry, 2023 Arlina Nurhapsari,1,2 Risya Cilmiaty,3 Adi Prayitno,3 Bambang Purwanto,4 Soetrisno Soetrisno5 1Doctoral Degree of Medical Science, Faculty of Medicine, Sebelas Maret University, Surakarta, Central Java, Indonesia; 2Department of Conservative Dentistry ...
Nurhapsari A +4 more
doaj
Frontiers in Physiology, 2018 Calcitonin gene-related peptide (CGRP) is a highly potent vasoactive peptide released from sensory nerves, which is now proposed to have protective effects in several cardiovascular diseases.
Zizheng Kee, X. Kodji, S. Brain
semanticscholar +1 more source
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
Allergy, EarlyView.ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source
The Journal of Headache and Pain, 2019 Background Monoclonal antibodies against calcitonin gene-related peptide (CGRP) or its receptor are efficacious for the prevention of migraine headaches.
Raffi Manoukian +5 more
doaj +1 more source
Encoding of danger by parabrachial CGRP neurons
Nature, 2018 Animals must respond to various threats to survive. Neurons that express calcitonin gene-related peptide in the parabrachial nucleus (CGRPPBN neurons) relay sensory signals that contribute to satiation and pain-induced fear behaviour, but it is unclear ...
C. Campos +3 more
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro +14 more
wiley +1 more source
Treatment of Persistent Post-traumatic Headache With the anti-CGRP Receptor Antibody Erenumab: a Case Report [PDF]
, 2021 Mike Papenhoff, Marcel Dudda
openalex +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
International Journal of Molecular Sciences, 2019 Neuron-glia interactions contribute to pain initiation and sustainment. Intra-ganglionic (IG) secretion of calcitonin gene-related peptide (CGRP) in the trigeminal ganglion (TG) modulates pain transmission through neuron-glia signaling, contributing to ...
Shaista Afroz +8 more
semanticscholar +1 more source
British Journal of Pharmacology, EarlyView.Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source