Results 21 to 30 of about 93,229 (254)

A multicenter comparative study of the performance of four rapid immunochromatographic tests for the detection of anti-Trypanosoma cruzi antibodies in Brazil

open access: yesFrontiers in Medicine, 2023
Diagnosis of Trypanosoma cruzi (T. cruzi) infection in the chronic phase of Chagas disease (CD) is performed by serologic testing. Conventional tests are currently used with very good results but require time, laboratory infrastructure, and expertise ...
Jacqueline Araújo Domingos Iturra   +11 more
doaj   +1 more source

Chagas' Heart Disease [PDF]

open access: yesClinical Cardiology, 2000
AbstractChagas' disease is caused by a protozoan parasite, Trypanosoma cruzi, that is transmitted to humans through the feces of infected bloodsucking insects in endemic areas of Latin America, or occasionally by nonvectorial mechanisms, such as blood transfusion.
A, Rassi, A, Rassi, W C, Little
openaire   +2 more sources

Current knowledge of Chagas-related heart disease among pediatric cardiologists in the United States

open access: yesBMC Cardiovascular Disorders, 2021
Background Chagas disease is a pathogenic parasitic infection with approximately 8 million cases worldwide and greater than 300,000 cases in the United States (U.S.).
Sanchi Malhotra   +4 more
doaj   +1 more source

Insights from quantitative and mathematical modelling on the proposed WHO 2030 goals for Chagas disease [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Chagas disease (CD) persists as one of the neglected tropical diseases (NTDs) with a particularly large impact in the Americas. The World Health Organization (WHO) recently proposed goals for CD elimination as a public health problem to be reached by ...
Collaborating Group on Chagas Disease Modelling
doaj   +1 more source

Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]

open access: yes, 2017
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz   +17 more
core   +3 more sources

Repolarization Parameters Are Associated With Mortality In Chagas Disease Patients In The United States

open access: yesIndian Pacing and Electrophysiology Journal, 2014
Objective: The goal of this study was to examine the association between ECG repolarization parameters and mortality in Chagas disease (CD) patients living in the United States.
Jason Bradfield, MD   +6 more
doaj   +1 more source

Scalable Access to N‑Acylindole Linkages: Enabling the Synthesis of Antitrypanosomal Noncanonical Cyclic Peptides for Chagas Disease

open access: yesAngewandte Chemie, EarlyView.
A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley   +2 more sources

Acute chagas disease: new global challenges for an old neglected disease. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health.
Daniela V Andrade   +2 more
doaj   +1 more source

Função do átrio esquerdo na miocardiopatia chagásica Function of the left atrium in the Chagas' cardiomyopathy

open access: yesArquivos Brasileiros de Cardiologia, 2005
OBJETIVO: Estudar a função do átrio esquerdo em portadores de miocardiopatia dilatada de etiologia chagásica e correlacioná-la à função diastólica e à classe funcional.
Maria do Carmo Pereira Nunes   +3 more
doaj   +1 more source

Cultural barriers to effective communication between Indigenous communities and health care providers in Northern Argentina: an anthropological contribution to Chagas disease prevention and control [PDF]

open access: yes, 2014
INTRODUCTION: Ninety percent of the aboriginal communities of Argentina are located in areas of endemic vectorial transmission of Chagas disease. Control activities in these communities have not been effective.
Braunstein, Jose Alberto   +5 more
core   +1 more source

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