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Chagas disease persists as a global public health problem due to the high morbidity and mortality burden. Despite the possibility of a cure and advances in transmission control, epidemiological transformations, such as urbanisation and globalisation, and the emerging importance of oral and vertical transmission mean that Chagas disease should be ...
Billick MJ, Silverberg SL.
exaly +6 more sources
An Overview on the Therapeutics of Neglected Infectious Diseases—Leishmaniasis and Chagas Diseases
Neglected tropical diseases (NTDs) as termed by WHO include twenty different infectious diseases that are caused by bacteria, viruses, and parasites. Among these NTDs, Chagas disease and leishmaniasis are reported to cause high mortality in humans and ...
Brindha J +2 more
doaj +2 more sources
Genetic Variants Associated with Life Expectancy in Patients with Chagas Disease [PDF]
Single nucleotide polymorphisms (SNPs), as common genetic variations, can influence biological processes. Identifying these variations is crucial for recognizing high-risk subgroups, guiding preventive strategies, and enabling personalized management ...
Mario Bruno Principato +10 more
doaj +2 more sources
Population Pharmacokinetic Study of Benznidazole in Pediatric Chagas Disease Suggests Efficacy despite Lower Plasma Concentrations than in Adults [PDF]
Introduction:Chagas disease, caused by the parasite Trypanosoma cruzi, can lead to long term cardiac morbidity. Treatment of children with benznidazole is effective, but no pediatric pharmacokinetics data are available and clinical pharmacology ...
Altcheh, Jaime Marcelo +9 more
core +44 more sources
Formas clínicas y diagnóstico de la enfermedad de Chagas e inmunosupresores
La enfermedad de Chagas constituye una infección severa de alta prevalencia en Argentina y otros países latinoamericanos. La administración de drogas reumáticas inmunosupresoras en estos pacientes, muchas veces es necesaria, pero no se conoce aún la ...
Darío Scublinsky +4 more
doaj +3 more sources
The Learning Curve for Peroral Endoscopic Myotomy in Latin America: A Slide to the Right? [PDF]
Background/Aims Peroral endoscopic myotomy (POEM) has been increasingly used for achalasia in Latin America, where Chagas disease is prevalent, and this makes POEM more challenging.
Michel Kahaleh +23 more
doaj +1 more source
Se realizaron encuestas serológicas y entomológicas para determinar la prevalencia de la enfermedad de Chagas, la presencia del vector y el índice tripano triatomino, en la población escolar de la parroquia Juan Gómez Rendón, en la provincia del Guayas,
Verónica Calderón, Jaime Buestán
doaj +1 more source
Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host.
Lina S. Prieto Cárdenas +6 more
doaj +1 more source
Epidemiologia de Triatominos en la Provincia de Río Negro
Chagas es una enfermedad endemoepidémica de transmisión vec-torial en la Provincia de Rio Negro causada por Trypanosoma cruzi, transmitido por insectos vectores denominados triatominos (vinchu-cas).
Crowley P +9 more
doaj +1 more source
Approximately 8 million people worldwide are infected by the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. After a latent period that can last years or decades, 10% to 30% of infected people develop serious complications, such as cardiomyopathy or gastrointestinal dysfunction.
Tustin, Aaron W., Bowman, Natalie M.
openaire +2 more sources

