Results 31 to 40 of about 240,071 (288)

Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]

, 2017
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz, Efraín A. Gómez, Felipe Martinez, Felix Ramires, Jean L. Rouleau, John J.V. McMurray, Karl Swedberg, Kenneth Dickstein, Lars Køber, Li Shen, Luis Eduardo Echeverría, Luiz Carlos Bodanese, Michael R. Zile, Milton Packer, null null, Pardeep S. Jhund, Scott D. Solomon, William T. Abraham   +17 more
core   +3 more sources

Protective immunity against Trypanosoma cruzi [PDF]

, 2009
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel, Padilla, Ángel Marcelo, Parodi Ramoneda, Cecilia María   +2 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

DETECÇÃO E CARACTERIZAÇÃO GENÉTICA DE VÍRUS SINCICIAL RESPIRATÓRIO HUMANO EM CASOS DE INFECÇÃO RESPIRATÓRIA AGUDA NO ESTADO DO AMAPÁ, BRASIL, DURANTE O ANO DE 2023

Brazilian Journal of Infectious Diseases, 2023
Introdução/Objetivos: As infecções respiratórias agudas (IRA) constituem um importante problema em saúde pública, especialmente aquelas desencadeadas pelo Vírus Sincicial Respiratório (VSR), um dos principais agentes virais associados à doença grave na ...
Luana Soares Barbagelata, Amanda Mendes Silva Cruz, Edivaldo Costa Sousa Júnior, Wanderley Dias das Chagas Júnior, Delana Andreza Melo Bezerra, Agatha Monike Silva Nunes, Edvaldo Tavares da Penha Júnior, Edna Maria Acunã de Souza, Alessandra Alves Polaro Lima, Andreia Santos Costa, Márcia Socorro Pereira Cavalcante, Fernando Neto Tavares, Mirleide Cordeiro dos Santos   +12 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Primeiro registro de epidemias causadas pelo vírus Oropouche nos Estados do Maranhão e Goiás, Brasil

Revista do Instituto de Medicina Tropical de São Paulo, 1989
Os autores descrevem a ocorrência de epidemias causadas pelo vírus Oropouche (ORO) nos Estados do Maranhão (MA) e Goiás (GO) em 1988. 36 amostras de vírus foram obtidas a partir da inoculação do sangue de 120 pacientes em camundongos recém nascidos.
Pedro Fernando da Costa Vasconcelos, Jorge Fernando Soares Travassos da Rosa, Sueli Corrêa Guerreiro, Nicolas Dégallier, Elizabeth Salbé Travassos da Rosa, Amélia Paes de Andrade Travassos da Rosa   +5 more
doaj   +1 more source

Identifying Health Centers in Honduras Infested with Rhodnius Prolixus Using the Seroprevalence of Chagas Disease in Children Younger than 13 Years. [PDF]

, 2005
The objective of this study is to determine if a Chagas disease protocol starting with a serological survey is as reliable at identifying insect-infested areas as one using the gold standard entomological survey.
Doust, J, Lucas, R, Spurling, G
core   +1 more source

Importancia en el sistema de salud de la infección por Treponema pallidum, la enfermedad de Chagas y el virus de la inmunodeficiencia humana 1 en amerindios de Argentina: un estudio observacional [PDF]

, 2017
El objetivo de este trabajo fue estimar la prevalencia de Treponema pallidum, Trypanosoma cruzi y virus de la inmunodeficiencia humana (HIV-1) en 5 comunidades originarias de Argentina.
Berini, Carolina Andrea, Biglione, Mirna Marcela, de Rissio, Ana María, Delfino, Cecilia María, Eirin, Maria Emilia, Espejo, Rogelio, Gallo Vaulet, Maria Lucia, Malan, Richard, Pedrozo, Williams René, Puca, Alberto, Rodríguez Fermepin, Marcelo   +10 more
core   +2 more sources

Assembling a True “Olympic Gel” From over 16 000 Combinatorial DNA Rings

Advanced Materials, EarlyView.
Olympic gels are an elusive class of soft matter, consisting of molecular networks held together purely by mechanically interlocked rings. Their topological structure promises unique properties and functions, but their synthesis has proven notoriously difficult.
Sarah K. Speed, Yu‐Hsuan Peng, Azra Atabay, Krishna Gupta, Toni Müller, Carolin Fischer, Ilka M. Hermes, Jens‐Uwe Sommer, Michael Lang, Elisha Krieg   +9 more
wiley   +1 more source

Persistence of experimental Rocio virus infection in the golden hamster (Mesocricetus auratus)

Memorias do Instituto Oswaldo Cruz, 2012
Rocio virus (ROCV) is an encephalitic flavivirus endemic to Brazil. Experimental flavivirus infections have previously demonstrated a persistent infection and, in this study, we investigated the persistence of ROCV infection in golden hamsters ...
Daniele Freitas Henriques, Juarez Antonio Simões Quaresma, Helen Thais Fuzii, Márcio Roberto Teixeira Nunes, Eliana Vieira Pinto da Silva, Valéria Lima Carvalho, Lívia Carício Martins, Samir Mansour Moraes Casseb, Jannifer Oliveira Chiang, Pedro Fernando da Costa Vasconcelos   +9 more
doaj   +1 more source