Results 11 to 20 of about 111,359 (301)
The Lancet, 2023 Chagas disease persists as a global public health problem due to the high morbidity and mortality burden. Despite the possibility of a cure and advances in transmission control, epidemiological transformations, such as urbanisation and globalisation, and
Andrea Silvestre de Sousa +3 more
semanticscholar +6 more sources
An Overview on the Therapeutics of Neglected Infectious Diseases—Leishmaniasis and Chagas Diseases
Frontiers in Chemistry, 2021 Neglected tropical diseases (NTDs) as termed by WHO include twenty different infectious diseases that are caused by bacteria, viruses, and parasites. Among these NTDs, Chagas disease and leishmaniasis are reported to cause high mortality in humans and ...
Brindha J +2 more
doaj +2 more sources
Chagas Disease: From Discovery to a Worldwide Health Problem
Frontiers in Public Health, 2019 Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in his honor, just over a century ago. He described the clinical aspects of the disease, characterized by its etiological agent (Trypanosoma cruzi) and identified its ...
Thaisa Lucas Sandri +2 more
exaly +2 more sources
The Learning Curve for Peroral Endoscopic Myotomy in Latin America: A Slide to the Right? [PDF]
Clinical Endoscopy, 2021 Background/Aims Peroral endoscopic myotomy (POEM) has been increasingly used for achalasia in Latin America, where Chagas disease is prevalent, and this makes POEM more challenging.
Michel Kahaleh +23 more
doaj +1 more source
Revista Científica de Ciencias Naturales y Ambientales, 2021 Se realizaron encuestas serológicas y entomológicas para determinar la prevalencia de la enfermedad de Chagas, la presencia del vector y el índice tripano triatomino, en la población escolar de la parroquia Juan Gómez Rendón, en la provincia del Guayas,
Verónica Calderón, Jaime Buestán
doaj +1 more source
Pharmaceuticals, 2022 Chagas and leishmaniasis are two neglected diseases considered as public health problems worldwide, for which there is no effective, low-cost, and low-toxicity treatment for the host.
Lina S. Prieto Cárdenas +6 more
doaj +1 more source
Epidemiologia de Triatominos en la Provincia de Río Negro
Ciencia Veterinaria, 2021 Chagas es una enfermedad endemoepidémica de transmisión vec-torial en la Provincia de Rio Negro causada por Trypanosoma cruzi, transmitido por insectos vectores denominados triatominos (vinchu-cas).
Crowley P +9 more
doaj +1 more source
Pediatrics In Review, 2016 Approximately 8 million people worldwide are infected by the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease. After a latent period that can last years or decades, 10% to 30% of infected people develop serious complications, such as cardiomyopathy or gastrointestinal dysfunction.
Tustin, Aaron W., Bowman, Natalie M.
openaire +2 more sources
Molecules, 2021 Several methoxybenzo[h]quinoline-3-carbonitrile analogs were designed and synthesized in a repositioning approach to developing compounds with anti-prostate cancer and anti-Chagas disease properties.
Hegira Ramírez +6 more
doaj +1 more source
Navigating drug repurposing for Chagas disease: advances, challenges, and opportunities
Frontiers in Pharmacology, 2023 Chagas disease is a vector-borne illness caused by the protozoan parasite Trypanosoma cruzi (T. cruzi). It poses a significant public health burden, particularly in the poorest regions of Latin America.
Exequiel O. J. Porta +2 more
semanticscholar +1 more source