Results 41 to 50 of about 312,210 (374)
Brazilian Journal of Infectious Diseases, 2023 Introdução/objetivos: Dentre as doenças infecciosas de grande importância para a saúde pública, a gripe ou influenza desempenha um papel significativo nos índices de morbidade e mortalidade em todo o mundo.
Wanderley Dias das Chagas Junior +12 more
doaj +1 more source
Feasibility, drug safety, and effectiveness of etiological treatment programs for Chagas disease in Honduras, Guatemala, and Bolivia: 10-year experience of Médecins Sans Frontières [PDF]
, 2009 BACKGROUND: Chagas disease (American trypanosomiasis) is a zoonotic or anthropozoonotic disease caused by the parasite Trypanosoma cruzi. Predominantly affecting populations in poor areas of Latin America, medical care for this neglected disease is often
Oliver Yun +35 more
core +2 more sources
Biomédica: revista del Instituto Nacional de Salud, 1999 Los estudios seroepidemiológicos para la detección de anticuerpos contra Trypanosoma cruzi requieren de un gran número de muestras y la obtención de sangre por punción venosa y su transporte se hacen difíciles y costosos.
Luis C. Orozco +8 more
doaj +1 more source
The Case for the Development of a Chagas Disease Vaccine: Why? How? When?
Tropical Medicine and Infectious Disease, 2021 Chagas disease is a major neglected tropical disease, transmitted predominantly by triatomine insect vectors, but also through congenital and oral routes. While endemic in the Americas, it has turned into a global disease.
Eric Dumonteil, Claudia P Herrera
semanticscholar +1 more source
Angewandte Chemie, EarlyView.A gram‐scale supply of bulbiferamide A, which features a rare N‐acylindole linkage and possesses potent inhibitory activity against Trypanosoma cruzi epimastigotes (IC50 = 4.1 µM)—the causative parasite of Chagas disease—was successfully achieved. Moreover, the cyclization strategy developed in this study facilitated the synthesis of noncanonical ...
Jie Zhang, Hugh Nakamura
wiley +2 more sources
Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region [PDF]
, 2017 The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases.
De Pablos, Luis Miguel +5 more
core +3 more sources
TcI isolates of Trypanosoma cruzi exploit the antioxidant network for enhanced intracellular survival in macrophages and virulence in mice [PDF]
, 2016 Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL),
Basombrío, Miguel Ángel Manuel +8 more
core +2 more sources
Chagas Disease in the United States: a Public Health Approach
Clinical Microbiology Reviews, 2019 Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal cardiac or gastrointestinal disease.
C. Bern +3 more
semanticscholar +1 more source
WHF IASC Roadmap on Chagas Disease
Global Heart, 2020 Background: Chagas Disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi, with some of the most serious manifestations affecting the cardiovascular system.
L. E. Echeverría +19 more
semanticscholar +1 more source
Acta Zoológica Lilloana, 2022 Se utilizó el método de prueba OMS para determinar la tolerancia de las ninfas en el 5º estado de Triatoma infestans. Las ninfas sobrevivientes mudaron normalmente y pusieron huevos viables.
Walter Hellmut Hack
doaj