Chronic phase of Chagas disease: why should it be treated? A comprehensive review
The pathogenesis and evolutive pattern of Chagas disease suggests that the chronic phase should be more widely treated in order to (i) eliminate Trypanosoma cruzi and prevent new inflammatory foci and the extension of tissue lesions, (ii) promote tissue ...
José Rodrigues Coura +1 more
doaj +1 more source
Regulatory lymphoid and myeloid cells determine the cardiac immunopathogenesis of Trypanosoma cruzi infection [PDF]
Chagas disease is a multisystemic disorder caused by the protozoan parasite Trypanosoma cruzi, which affects ~8 million people in Latin America, killing 7,000 people annually.
Abrahamsohn +94 more
core +3 more sources
Proteomic inventory of myocardial proteins from patients with chronic Chagas' cardiomyopathy [PDF]
Priscila Camillo Teixeira +7 more
openalex +2 more sources
Incidence and Predictors of Progression to Chagas Cardiomyopathy: Long-Term Follow-Up of Trypanosoma cruzi –Seropositive Individuals [PDF]
Maria Carmo P. Nunes +19 more
openalex +1 more source
A multi-parametric analysis of Trypanosoma cruzi infection: common pathophysiologic patterns beyond extreme heterogeneity of host responses [PDF]
The extreme genetic diversity of the protozoan Trypanosoma cruzi has been proposed to be associated with the clinical outcomes of the disease it provokes: Chagas disease (CD).
Chillón-Marinas, Carlos +6 more
core +3 more sources
Integrated control of chagas disease for its elimination as public health problem: A review [PDF]
Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to disability in Latin America.
Segura, Elsa Leonor +1 more
core +4 more sources
Importance of Developing New Tools to Assess Cardiac Amyloidosis Using Echocardiography
Echocardiography, Volume 42, Issue 8, August 2025.
Claudio Tinoco Mesquita +2 more
wiley +1 more source
Chagas disease cardiomyopathy is a parasite-driven inflammatory disease to which there are no effective treatments. Here we evaluated the therapeutic potential of N,N-dimethylsphingosine(DMS), which blocks the production of sphingosine-1-phosphate(S1P ...
Juliana Fraga Vasconcelos +10 more
doaj +1 more source

