Results 101 to 110 of about 235,727 (237)

Natural Products from Mexican Medicinal Plants as Promising Trypanocidal Drugs

open access: yesChemistrySelect, Volume 10, Issue 37, October 6, 2025.
Chagas disease (American Trypanosomiasis) is caused by the protozoan Trypanosoma cruzi. Worldwide it is one of the seventeen neglected tropical diseases. There is a need of new drugs. This review assesses the literature (2012‐2024) of secondary metabolites isolated from Mexican plants active against this parasite.
Karla Daniela Rodríguez‐Hernández   +2 more
wiley   +1 more source

Lack of correlation for anti-β1 autoantibodies and cardioelectric disorders in chagas cardiomyopathy [PDF]

open access: diamond, 2023
Analia G. Paolucci   +5 more
openalex   +1 more source

Association between positive serology for COVID-19 and chagas cardiomyopathy progression: The SaMi-Trop project

open access: yesTravel Medicine and Infectious Disease
Background: Chagas Disease (CD) can cause Chagas cardiomyopathy. The new coronavirus disease (COVID-19) also affects the cardiovascular system and may worsen Chagas cardiomyopathy.
Ariela Mota Ferreira   +15 more
doaj   +1 more source

Activation of Human CD11b+ B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease

open access: yesFrontiers in Immunology, 2019
B-cells mediate humoral adaptive immune response via the production of antibodies and cytokines, and by inducing T-cell activation. These functions can be attributed to distinct B-cell subpopulations. Infection with Trypanosoma cruzi, the causative agent
Livia Silva Araújo Passos   +15 more
doaj   +1 more source

The Impact of the Spatial Distribution of Ventricular Extrasystoles on Implantable Cardioverter‐Defibrillator Recipients

open access: yesPacing and Clinical Electrophysiology, Volume 48, Issue 10, Page 1157-1166, October 2025.
Distribution of distinct topographies and their relationship with NYHA classes and therapies. Each of the 111 dots represents a distinct PVC topography recorded in the 12L‐AECGs. Black dots represent PVC associated with patients classified as NYHA class I, green dots with NYHA class II, and yellow dots with NYHA class III.
Carlos Arthur Hansel Diniz da Costa   +7 more
wiley   +1 more source

Trypanosoma Cruzi Lineages Shape Macrophage Cytokine Profiles in Single and Mixed Infections

open access: yesParasite Immunology, Volume 47, Issue 9, September 2025.
ABSTRACT Chagas disease, caused by Trypanosoma cruzi, exhibits a wide clinical spectrum, which is influenced by the parasite's extensive genetic diversity. Growing evidence indicates that human infections are often multiclonal, involving a dynamic population of parasite clones, collectively termed the “cruziome”. The immunological consequences of these
Cecília Luiza Pereira   +5 more
wiley   +1 more source

Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy: Clinical Practice Update

open access: yesJournal of Education, Health and Sport
Background: Chronic Chagas cardiomyopathy is an arrhythmogenic, fibrosis-prone form of heart failure that develops years after Trypanosoma cruzi infection. Standard therapy has largely been extrapolated from non-Chagas trials.
Katarzyna Skibicka   +3 more
doaj   +1 more source

Circulating Plasma MicroRNA-208a as Potential Biomarker of Chronic Indeterminate Phase of Chagas Disease

open access: yesFrontiers in Microbiology, 2018
Chagas cardiomyopathy is the most severe clinical manifestation of chronic Chagas disease. The disease affects most of the Latin American countries, being considered one of the leading causes of morbidity and death in the continent.
Leandra Linhares-Lacerda   +14 more
doaj   +1 more source

Profile of soluble cell adhesion molecules as potential biomarkers in the cardiac stages of chronic Chagas disease

open access: yesFrontiers in Immunology
Chagas cardiomyopathy is the most severe chronic manifestation and leading cause of mortality in the disease. Chronic inflammation, resulting from persistent infection by T.
Victor Vaitkevicius-Antão   +11 more
doaj   +1 more source

Ventricular arrhythmias in Chagas disease

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2015
Sudden death is one of the most characteristic phenomena of Chagas disease, and approximately one-third of infected patients develop life-threatening heart disease, including malignant ventricular arrhythmias.
Marco Paulo Tomaz Barbosa   +3 more
doaj   +1 more source

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