Results 51 to 60 of about 2,186,596 (297)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Effect of chain stiffness on the structure of single-chain polymer nanoparticles [PDF]
Journal of Physics: Condensed Matter, 2017 20 pages, 17 ...
Angel J Moreno +5 more
openaire +5 more sources
A structural database of chain–chain and domain–domain interfaces of proteins
Protein Science, 2022 Abstract In this study, we mined the PDB and created a structural library of 178,465 interfaces that mediate protein–protein/domain–domain interactions. Interfaces involving the same CATH fold(s) were clustered together. Our analysis of the library reveals similarities between chain–chain and domain–domain interactions.
Neeladri Sen, M.S. Madhusudhan
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Crystals, 2021 The luminescence of materials in condensed phases is affected by not only their molecular structures but also their aggregated structures. In this study, we designed new liquid-crystalline luminescent materials based on biphenylacetylene with a bulky ...
Hussain Sami +6 more
doaj +1 more source
Formation of Chain-Folded Structures from Supercooled Polymer Melts
, 2000 The formation of chain-folded structures from the melt is observed in molecular dynamics simulations resembling the lamellae of polymer crystals. Crystallization and subsequent melting temperatures are related linearly to the inverse lamellar thickness ...
Armistead K. A. +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
CHAIN STRUCTURES IN SCHEDULES TASKS
Prikladnaya diskretnaya matematika, 2016 Summary: Some algorithms for constructing the following schedules are developed: 1) one-processor schedule with a partial precedence, 2) a multiprocessor schedule without idle time and conditions of partial precedence.
openaire +2 more sources
On the structure of flat chains modulo p [PDF]
Advances in Calculus of Variations, 2017 Abstract In this paper, we prove that every equivalence class in the quotient group of integral 1-currents modulo p in Euclidean space contains an integral current, with quantitative estimates on its mass and the mass of its boundary.
Marchese A., Stuvard S.
openaire +6 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source