Results 61 to 70 of about 28,625 (273)

Direct Quantification of Protein–Protein Interactions in Living Bacterial Cells

open access: yesAdvanced Science, EarlyView.
Quantitative measurement of protein–protein interactions in living cells is vital for biotechnology applications. Fluorescence resonance energy transfer (FRET) signals in bacterial cells are often weak, leading to false‐positive. Quantitative FRET measurements are implemented to overcome the weak FRET signal.
Soojung Yi   +12 more
wiley   +1 more source

Cytotoxic Activity of Methoxy-4’amino Chalcone Derivatives Against Leukemia Cell Lines

open access: yesMCBS (Molecular and Cellular Biomedical Sciences), 2019
Background: Chemotherapy is a common treatment for leukemia as well as in other cancer treatment. The lack of tumor selectivity and development of multi-drug resistance by chemotherapy caused the development of new strategy in cancer treatment become a ...
Arina Novilla   +4 more
doaj   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

open access: yesAdvanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang   +10 more
wiley   +1 more source

Trans-chalcone activity against Trichophyton rubrum relies on an interplay between signaling pathways related to cell wall integrity and fatty acid metabolism

open access: yesBMC Genomics, 2019
Background Trichophyton rubrum is the main etiological agent of skin and nail infections worldwide. Because of its keratinolytic activity and anthropophilic nature, infection models based on the addition of protein substrates have been employed to assess
Tamires Aparecida Bitencourt   +11 more
doaj   +1 more source

Integrated Green Biorefinery for the Production of Anthocyanins, Fermentable Sugars, and High Pure Lignin from Miscanthus × giganteus

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Integrated production of pigments, fermentation sugars, and pure lignin has been investigated for the creation of profitable biorefinery developments. Choline chloride‐based natural deep eutectic solvents possess unique solvent capabilities to interact with plant cell wall components to disintegrate lignin‐carbohydrate complex.
Tirath Raj, Vijay Singh
wiley   +1 more source

Does the abiotic environment influence the distribution of flower and fruit colors?

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Premise Color in flowers and fruits carries multiple functions, from attracting animal partners (pollinators, dispersers) to mitigating environmental stress (cold, drought, UV‐B). With research historically focusing on biotic interactions as selective agents, however, it remains unclear whether abiotic stressors impact flower and fruit colors ...
Agnes S. Dellinger   +3 more
wiley   +1 more source

Antiproliferative Effect of Acridine Chalcone Is Mediated by Induction of Oxidative Stress

open access: yesBiomolecules, 2020
Chalcones are naturally occurring phytochemicals with diverse biological activities including antioxidant, antiproliferative, and anticancer effects. Some studies indicate that the antiproliferative effect of chalcones may be associated with their pro ...
Peter Takac   +6 more
doaj   +1 more source

Antiviral effects and mechanism of Qi pi pill against influenza viruses

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang   +10 more
wiley   +1 more source

Plant defense multigene families: I. Divergence of Fusarium solani-induced expression in Pisum and Lathyrus [PDF]

open access: yesarXiv, 2003
The defense response in plants challenged with pathogens is characterized by the activation of a diverse set of genes. Many of the same genes are induced in the defense responses of a wide range of plant species. How plant defense gene families evolve may therefore provide an important clue to our understanding of how disease resistance evolves ...
arxiv  

4-({4-[(2E)-3-(2,5-Dimethoxyphenyl)prop-2-enoyl]phenyl}amino)-4-oxobutanoic Acid

open access: yesMolbank, 2017
A dimethoxy amide chalcone has been synthesized in a two-step reaction. First, an amine chalcone was synthesized by the reaction of 4′-aminoacetophenone and 2,5-dimethoxybenzaldehyde using 40% NaOH solution as a catalyst in ethanol, and then followed by ...
Hery Suwito   +4 more
doaj   +1 more source

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