Results 51 to 60 of about 23,013 (219)

Simple chalcones and bis-chalcones ethers as possible pleiotropic agents

Journal of Enzyme Inhibition and Medicinal Chemistry, 2015
The synthesis, the antioxidative properties and the lipoxygenase (LOX) and acetylcholinesterase (AChE) inhibition of a number of 4-hydroxy-chalcones diversely substituted as well as of a series of bis-chalcones ether derivatives are reported. The chalcones derivatives were readily produced using a Claisen-Schmidt condensation in a ultra sound bath in ...
Liargkova, T., Hadjipavlou-Litina, D.J., Koukoulitsa, C., Voulgari, E., Avgoustakis, C.   +4 more
openaire   +3 more sources

Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α‐Mangostin: A Structure–Activity Relationship Insight

ChemFoodChem, EarlyView.
Free phenolic hydroxyl groups in the chemical structure of the natural xanthone α‐mangostin (MGT) contribute positively to achieving the anticancer profile against murine colon cancer, murine triple negative breast cancer, and human osteosarcoma cancer. ABSTRACT The α‐mangostin (MGT) is a natural xanthone obtained from the pericarp of mangosteen fruit (
Otávio Augusto Chaves, Afonso Santine M. M. Velez, Lívia Stenico, Douglas Chaves de Alcântara Pinto, Debora Decote‐Ricardo, Eliezer Avila Gandra, Marco Edilson Freire de Lima, Carlos Serpa   +7 more
wiley   +1 more source

Evaluation of the anti-tumor and immunomodulatory effects of synthetic chalcones in a tumor mouse model [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2019
Introduction: Traditional treatment of cancer by using chemotherapy not only kills cancer cells but also normal cells. It also fails in the complete prevention of the spread of tumor cells. Chalcone have several biological activities, such as antioxidant,
Mohamed Nasef, Mohamed Gaber, Asmaa El Gamal, Mohamed Salem   +3 more
doaj   +1 more source

Chalcones X : Syntheses of Naphthalene Chalcone Analogues

, 1972
Department of Chemistry, H. B. Technological Institute, Kanpur Received 23 October 1971; revised MSS received 27 March 1972 Chalcones X : Syntheses of Naphthalene Chalcone Analogues.
SHYAM SUNDER MISRA, DINKAR
openaire   +2 more sources

Green Synthesis of Chalcone Derivatives Using Chalcones as Precursor

, 2022
Recently, the use of green methodologies like sonication, use of ionic liquids, etc. attracted the attention of researchers in the field of organic synthesis as they have advantages such as mild reaction conditions, environmentally benign procedures, etc.
Surbhi Dhadda, Prakash Giri Goswami, Himanshu Sharma   +2 more
openaire   +1 more source

Synthesis of the Core Tetracycle of the Spirobiflavonoid Daphnodorin C

European Journal of Organic Chemistry, EarlyView.
Core spirotetracycle of daphnodorin C: Oxidative ring contraction of benzofuro[3,2‐b]chromenones affords novel 2,3′‐spirobi[benzofuran]diones, rather than the isomeric spiroketals. The first synthesis of the spirobi[benzofuran]dione core structure of the spirobiflavonoid daphnodorin C is described.
Lukas Heemann, Peter G. Jones, Thomas Lindel   +2 more
wiley   +1 more source

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

European Journal of Organic Chemistry, EarlyView.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

Effects of high‐moisture extrusion processing on reducing anti‐nutritional factors and allergenicity in plant‐based materials—A mini review

Food Biomacromolecules, EarlyView.
Abstract The rising demand for plant‐based meat alternatives has had advancements in processing technologies such as extrusion to meet consumer preferences for enhanced sensory qualities and nutritional benefits. High moisture extrusion (HME), a thermo‐mechanical process employing elevated moisture levels (40%–70%), has emerged as a promising method ...
Nur Hameedah Binte Ramadhan, Yuzhu Mao, Juan Du   +2 more
wiley   +1 more source

Advances in protein–polyphenol complexation: Unraveling mechanisms, modulation, and functional outcomes

Food Biomacromolecules, EarlyView.
Abstract Polyphenolic compounds have attracted increasing market demand and extensive attention due to their potential health benefits and bioactivities. Meanwhile, proteins are widely used in the food industry for their nutritional and functional properties. However, the application of proteins in the food industry is often limited by challenges, such
Fang Li, Ziming Xu, Tian Zhao, Gongshuai Song, Danli Wang, Tinglan Yuan, Ling Li, Jinyan Gong   +7 more
wiley   +1 more source

Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin

Frontiers in Microbiology, 2017
Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable.
Bing Zhang, Bing Zhang, Zihao Teng, Xianhe Li, Gejin Lu, Xuming Deng, Xuming Deng, Xiaodi Niu, Jianfeng Wang, Jianfeng Wang   +9 more
doaj   +1 more source