Results 31 to 40 of about 30,495 (265)
Sintesis Khalkon dan Uji Aktivitas Tabir Surya Secara In Vitro
Indonesian Journal of Pharmaceutical Education, 2023 Synthesis of 2',4'-dihydroxy-3,4-dimethoxychalcone and in vitro test of its sunscreen activity have been carried out. Chalcone was synthesized from 3,4-dimethoxybenzaldehyde and 2,4-dihydroxyacetophenone through Claisen-Schmidt condensation.
Dewi Darmiyani Napu
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Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
Allergology International, 2010 Background: : Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes.
Chiaki Iwamura +5 more
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Chempublish Journal, 2023 Molecular docking study of 6 chalcone analogues with protein target from the crystallographic structure modeling of Bcl-2 protein with PDB code 2W3L was carried out using computational media using the Molecular Operating Environment (MOE) program.
Neni Frimayanti +2 more
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Chalcone Scaffold: A masterpiece for medicinal chemistry recent biological insights [PDF]
Journal of Advanced Biomedical and Pharmaceutical Sciences, 2023 In medicinal chemistry, privileged structures are frequently used as an effective template for finding new drugs. Chalcone is a typical simple sugar that occurs in a wide variety of naturally occurring compounds. Chalcone derivatives are also prepared in
Mohamed Abdelaziz +3 more
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Bangladesh Journal of Pharmacology, 2016 The aim of the current study was to investigate the in vitro and in vivo anti-tumor effects of naringenin chalcone in U87MG human glioblastoma cells and in xenograft mice model.
Shuai Zhang +4 more
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Synthesis and Biological Evaluation of Amino Chalcone Derivatives as Antiproliferative Agents
Molecules, 2020 Chalcone is a common scaffold found in many biologically active compounds. The chalcone scaffold was also frequently utilized to design novel anticancer agents with potent biological efficacy.
Chao-Fan Lu +14 more
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Thermal study of chalcones [PDF]
Journal of Thermal Analysis and Calorimetry, 2018 Chalcones α-β-unsaturated ketones are found in large plant species. Synthesis of chalcones and its three analogues hydroxy group at 2′, 3′ and 4′ positions (2–4) was carried out. The studies of thermal behavior were made by thermogravimetry (TG) and differential scanning calorimetry, both under oxygen and nitrogen purge gases.
Marcelo Kobelnik +5 more
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Acta Pharmaceutica Sinica B, 2018 Prenylflavonoids are valuable natural products that have diverse biological properties, and are usually generated biologically by multiple metabolic enzymes in nature.
Jianhua Li +6 more
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Study of Michael addition on chalcones and or chalcone analogues
Journal of Saudi Chemical Society, 2012 AbstractMichael addition reaction of 1,3-diphenyl-propenone 1a, e, and f with o-amino thiophenol in the presence of indium trichloride gave the benzothiazine derivatives 2a–c. Condensation of the compound 1a, e with o-phenylene diamine in triethylamine gave the benzodiazepine derivatives 3a–b.
Al-Jaber, Nabila A. +2 more
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Chalcone suppresses tumor growth through NOX4-IRE1α sulfonation-RIDD-miR-23b axis
Redox Biology, 2021 Chalcone is a polyphenolic compound found abundantly in natural plant components. They have been acclaimed as potential antitumor compounds in multiple tumor cells. However, not much attention has been paid to elucidate its antitumor mechanism of action.
Hyun-Kyoung Kim +8 more
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