Results 21 to 30 of about 33,682 (280)

Green light LED activated ligation of a scalable, versatile chalcone chromophore

open access: yes, 2021
Herein we introduce a photoreactive chalcone moiety that can be synthesized at a scale of several grams with ease, and efficiently undergoes a [2 + 2] photocycloaddition with light up to just below 500 nm as determined by an action plot.
De Bruycker, Kevin   +5 more
core   +1 more source

Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase

open access: yesJournal of Natural Products, 2023
By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation-thiolation didomain, which catalyzes the formation of naringenin chalcone, was found. Structural prediction and molecular docking analysis indicated that a C-terminal thioesterase domain was involved in the Claisen-type cyclization.
Sho Furumura   +7 more
openaire   +2 more sources

A conserved strategy of chalcone isomerase-like protein to rectify promiscuous chalcone synthase specificity

open access: yesNature Communications, 2020
Chalcone synthase is the first committed enzyme in the plant flavonoid biosynthesis pathway, yet shows low product specificity in vitro. Here Waki et al.
Toshiyuki Waki   +20 more
doaj   +1 more source

The Benefits of Chalcone and Its Derivatives as Antibacterial Agents: A Review

open access: yesBIO Web of Conferences, 2020
Chalcone is a secondary metabolite compound found in plants. Chalcones contain two aryl rings, namely ring A and B which connected to the α,β unsaturated ketones.
Mustikasari Kamilia   +1 more
doaj   +1 more source

Chalcone-Based Pyridinium Salts and Their Diastereoselective Dearomatization To Access Bibridged Benzoazepines

open access: yes, 2020
New chalcone-based pyridinium salts have been successfully exploited, which could smoothly participate in the highly diastereoselective dearomatization with binucleophilic enaminones by taking advantage of their multiple reactive sites to construct ...
Zhao-Hui Cui (6872906)   +5 more
core   +1 more source

2-Hydroxychalcone as a Potent Compound and Photosensitizer Against Dermatophyte Biofilms

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Dermatophytes, fungi that cause dermatophytosis, can invade keratinized tissues in humans and animals. The biofilm-forming ability of these fungi was described recently, and it may be correlated with the long treatment period and common recurrences of ...
Níura Madalena Bila   +9 more
doaj   +1 more source

A new member of the chalcone synthase (CHS) family in sugarcane

open access: yesGenetics and Molecular Biology, 2001
Sequences from the sugarcane expressed sequence tag (SUCEST) database were analyzed based on their identities to genes encoding chalcone-synthase-like enzymes.
Miriam G.G. Contessotto   +3 more
doaj   +1 more source

Sintesis Khalkon dan Uji Aktivitas Tabir Surya Secara In Vitro

open access: yesIndonesian Journal of Pharmaceutical Education, 2023
Synthesis of 2',4'-dihydroxy-3,4-dimethoxychalcone and in vitro test of its sunscreen activity have been carried out. Chalcone was synthesized from 3,4-dimethoxybenzaldehyde and 2,4-dihydroxyacetophenone through Claisen-Schmidt condensation.
Dewi Darmiyani Napu
doaj   +1 more source

Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells

open access: yesAllergology International, 2010
Background: : Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes.
Chiaki Iwamura   +5 more
doaj   +1 more source

Molecular Docking Study of Chalcone Analogue Compounds with Hydroxy and Methoxy Subtituents as Bcl-2 Inhibitors

open access: yesChempublish Journal, 2023
Molecular docking study of 6 chalcone analogues with protein target from the crystallographic structure modeling of Bcl-2 protein with PDB code 2W3L was carried out using computational media using the Molecular Operating Environment (MOE) program.
Neni Frimayanti   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy