Results 21 to 30 of about 23,013 (219)
Bangladesh Journal of Pharmacology, 2016 The aim of the current study was to investigate the in vitro and in vivo anti-tumor effects of naringenin chalcone in U87MG human glioblastoma cells and in xenograft mice model.
Shuai Zhang +4 more
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Chempublish Journal, 2023 Molecular docking study of 6 chalcone analogues with protein target from the crystallographic structure modeling of Bcl-2 protein with PDB code 2W3L was carried out using computational media using the Molecular Operating Environment (MOE) program.
Neni Frimayanti +2 more
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Acta Pharmaceutica Sinica B, 2018 Prenylflavonoids are valuable natural products that have diverse biological properties, and are usually generated biologically by multiple metabolic enzymes in nature.
Jianhua Li +6 more
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Synthesis and Biological Evaluation of Amino Chalcone Derivatives as Antiproliferative Agents
Molecules, 2020 Chalcone is a common scaffold found in many biologically active compounds. The chalcone scaffold was also frequently utilized to design novel anticancer agents with potent biological efficacy.
Chao-Fan Lu +14 more
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Chalcone Scaffold: A masterpiece for medicinal chemistry recent biological insights [PDF]
Journal of Advanced Biomedical and Pharmaceutical Sciences, 2023 In medicinal chemistry, privileged structures are frequently used as an effective template for finding new drugs. Chalcone is a typical simple sugar that occurs in a wide variety of naturally occurring compounds. Chalcone derivatives are also prepared in
Mohamed Abdelaziz +3 more
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Angewandte Chemie, EarlyView.One catalyst for two products: CO acts as a molecular trigger for adaptive alkyne hydrogenation using supported Pd nanoparticles. The catalyst reversibly switches between the formation of alkanes under H2 and Z‐alkenes under H2/CO for 37 structurally diverse alkynes.
Manisha Durai +7 more
wiley +2 more sources
Regulation of autophagy-related gene expressions by Trans-chalcone in the lungs of adult male rats [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریزBackground. Autophagy is responsible for maintaining cellular homeostasis by degrading and recycling macromolecules and unwanted intracellular components, such as damaged organelles.
Fatemeh Salehi Mazdeh +4 more
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Chalcone suppresses tumor growth through NOX4-IRE1α sulfonation-RIDD-miR-23b axis
Redox Biology, 2021 Chalcone is a polyphenolic compound found abundantly in natural plant components. They have been acclaimed as potential antitumor compounds in multiple tumor cells. However, not much attention has been paid to elucidate its antitumor mechanism of action.
Hyun-Kyoung Kim +8 more
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SYNTHESIS AND CYTOTOXIC ACTIVITY OF CHALCONE DERIVATIVES ON HUMAN BREAST CANCER CELL LINES
Indonesian Journal of Chemistry, 2012 Chalcone, an α,β-unsaturated ketone, has been shown have many biological activities such as anticancer and antifungi. This research was conducted to synthesize the chalcone derivatives and to obtain their cytotoxic activity on human cervix cancer cell ...
Nuraini Harmastuti +4 more
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Natural Product Rottlerin Derivatives Targeting Quorum Sensing
Molecules, 2021 Rottlerin is a natural product consisting of chalcone and flavonoid scaffolds, both of which have previously shown quorum sensing (QS) inhibition in various bacteria.
Dittu Suresh +6 more
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