Results 11 to 20 of about 48,655 (255)
Hepatoprotective and antifibrotic effects of trans-chalcone against bile duct ligation-induced liver fibrosis in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Several lines of research have shown that hepatic fibrosis is one of the leading causes of death worldwide. Trans-chalcone is a flavonoid precursor with anti-oxidant and anti-inflammatory effects.
Faezeh Javadi +5 more
doaj +1 more source
Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities. [PDF]
, 2017 Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food.
Jafari, Mahtab +3 more
core +1 more source
Indonesian Journal of Chemistry, 2018 The synthesis of chalcone derivatives as target compounds and anticancer test against breast (T47D) and colon (WiDr) cell line had been performed.
Chairil Anwar +5 more
doaj +1 more source
Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]
, 2012 Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Tomasch, Miriam +3 more
core +1 more source
The solubility and stability of heterocyclic chalcones compared with trans-chalcone [PDF]
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2020 Heterocyclic chalcones are a recently explored subgroup of chalcones that have sparked interest due to their significant antibacterial and antifungal capabilities. Herein, the structure and solubility of two such compounds, (E)-1-(1H-pyrrol-2-yl)-3-(thiophen-2-yl)prop-2-en-1-one and (E)-3-phenyl-1-(1H-pyrrol-2-yl)prop-2-en-1-one, are assessed.
Stephen G. Sweeting +8 more
openaire +4 more sources
2-Hydroxychalcone as a Potent Compound and Photosensitizer Against Dermatophyte Biofilms
Frontiers in Cellular and Infection Microbiology, 2021 Dermatophytes, fungi that cause dermatophytosis, can invade keratinized tissues in humans and animals. The biofilm-forming ability of these fungi was described recently, and it may be correlated with the long treatment period and common recurrences of ...
Níura Madalena Bila +9 more
doaj +1 more source
Design and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold [PDF]
, 2019 The virtual screening of a library of chalcone derivatives led us to the identification of potential new MDM2 ligands. The chalcones with the best docking scores obeying the Lipinski rule of five were subsequently prepared by base-catalyzed aldol ...
Cidade, Honorina +12 more
core +3 more sources
Nature Communications, 2020 Chalcone synthase is the first committed enzyme in the plant flavonoid biosynthesis pathway, yet shows low product specificity in vitro. Here Waki et al.
Toshiyuki Waki +20 more
doaj +1 more source
The Benefits of Chalcone and Its Derivatives as Antibacterial Agents: A Review
BIO Web of Conferences, 2020 Chalcone is a secondary metabolite compound found in plants. Chalcones contain two aryl rings, namely ring A and B which connected to the α,β unsaturated ketones.
Mustikasari Kamilia +1 more
doaj +1 more source
Sintesis Khalkon dan Uji Aktivitas Tabir Surya Secara In Vitro
Indonesian Journal of Pharmaceutical Education, 2023 Synthesis of 2',4'-dihydroxy-3,4-dimethoxychalcone and in vitro test of its sunscreen activity have been carried out. Chalcone was synthesized from 3,4-dimethoxybenzaldehyde and 2,4-dihydroxyacetophenone through Claisen-Schmidt condensation.
Dewi Darmiyani Napu
doaj +1 more source