Results 11 to 20 of about 23,013 (219)
Molecules, 2023 Chalcones are interesting anticancer drug candidates which have attracted much interest due to their unique structure and their extensive biological activity.
Mahmoud I. M. Darwish +10 more
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Indonesian Journal of Chemistry, 2018 The synthesis of chalcone derivatives as target compounds and anticancer test against breast (T47D) and colon (WiDr) cell line had been performed.
Chairil Anwar +5 more
doaj +1 more source
The Benefits of Chalcone and Its Derivatives as Antibacterial Agents: A Review
BIO Web of Conferences, 2020 Chalcone is a secondary metabolite compound found in plants. Chalcones contain two aryl rings, namely ring A and B which connected to the α,β unsaturated ketones.
Mustikasari Kamilia +1 more
doaj +1 more source
Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase
Journal of Natural Products, 2023 By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation-thiolation didomain, which catalyzes the formation of naringenin chalcone, was found. Structural prediction and molecular docking analysis indicated that a C-terminal thioesterase domain was involved in the Claisen-type cyclization.
Sho Furumura +7 more
openaire +2 more sources
Nature Communications, 2020 Chalcone synthase is the first committed enzyme in the plant flavonoid biosynthesis pathway, yet shows low product specificity in vitro. Here Waki et al.
Toshiyuki Waki +20 more
doaj +1 more source
2-Hydroxychalcone as a Potent Compound and Photosensitizer Against Dermatophyte Biofilms
Frontiers in Cellular and Infection Microbiology, 2021 Dermatophytes, fungi that cause dermatophytosis, can invade keratinized tissues in humans and animals. The biofilm-forming ability of these fungi was described recently, and it may be correlated with the long treatment period and common recurrences of ...
Níura Madalena Bila +9 more
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Hepatoprotective and antifibrotic effects of trans-chalcone against bile duct ligation-induced liver fibrosis in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Several lines of research have shown that hepatic fibrosis is one of the leading causes of death worldwide. Trans-chalcone is a flavonoid precursor with anti-oxidant and anti-inflammatory effects.
Faezeh Javadi +5 more
doaj +1 more source
A new member of the chalcone synthase (CHS) family in sugarcane
Genetics and Molecular Biology, 2001 Sequences from the sugarcane expressed sequence tag (SUCEST) database were analyzed based on their identities to genes encoding chalcone-synthase-like enzymes.
Miriam G.G. Contessotto +3 more
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Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
Allergology International, 2010 Background: : Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes.
Chiaki Iwamura +5 more
doaj +1 more source
Sintesis Khalkon dan Uji Aktivitas Tabir Surya Secara In Vitro
Indonesian Journal of Pharmaceutical Education, 2023 Synthesis of 2',4'-dihydroxy-3,4-dimethoxychalcone and in vitro test of its sunscreen activity have been carried out. Chalcone was synthesized from 3,4-dimethoxybenzaldehyde and 2,4-dihydroxyacetophenone through Claisen-Schmidt condensation.
Dewi Darmiyani Napu
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