Results 41 to 50 of about 33,682 (280)

Chalcone-based imidazo[2,1-b]thiazole derivatives: synthesis, crystal structure, potent anticancer activity, and computational studies

open access: yes, 2023
In this work, two novel chalcone-based imidazothiazole derivatives ITC-1 and ITC-2 were synthesized and characterized by 1H NMR, 13C NMR and high-resolution mass spectrometry with electrospray ionization, and chemical structure of ITC-1 was confirmed by ...
Burçin Türkmenoğlu (17456071)   +9 more
core   +1 more source

Natural Product Rottlerin Derivatives Targeting Quorum Sensing

open access: yesMolecules, 2021
Rottlerin is a natural product consisting of chalcone and flavonoid scaffolds, both of which have previously shown quorum sensing (QS) inhibition in various bacteria.
Dittu Suresh   +6 more
doaj   +1 more source

SYNTHESIS AND CYTOTOXIC ACTIVITY OF CHALCONE DERIVATIVES ON HUMAN BREAST CANCER CELL LINES

open access: yesIndonesian Journal of Chemistry, 2012
Chalcone, an α,β-unsaturated ketone, has been shown have many biological activities such as anticancer and antifungi. This research was conducted to synthesize the chalcone derivatives and to obtain their cytotoxic activity on human cervix cancer cell ...
Nuraini Harmastuti   +4 more
doaj   +1 more source

Comparative Molecular Mechanisms of Biosynthesis of Naringenin and Related Chalcones in Actinobacteria and Plants: Relevance for the Obtention of Potent Bioactive Metabolites

open access: yesAntibiotics, 2022
Naringenin and its glycosylated derivative naringin are flavonoids that are synthesized by the phenylpropanoid pathway in plants. We found that naringenin is also formed by the actinobacterium Streptomyces clavuligerus, a well-known microorganism used to
Juan F. Martín, Paloma Liras
doaj   +1 more source

Chalcone-Thiazole Hybrids: Rational Design, Synthesis, and Lead Identification against 5‑Lipoxygenase

open access: yes, 2019
A hybrid pharmacophore approach is used to design and synthesize novel chalcone-thiazole hybrid molecules. Herein, thiazole has been hybridized with chalcone to obtain a new class of 5-LOX inhibitors.
Mukesh Doble (412086)   +2 more
core   +1 more source

Study of Michael addition on chalcones and or chalcone analogues

open access: yesJournal of Saudi Chemical Society, 2012
AbstractMichael addition reaction of 1,3-diphenyl-propenone 1a, e, and f with o-amino thiophenol in the presence of indium trichloride gave the benzothiazine derivatives 2a–c. Condensation of the compound 1a, e with o-phenylene diamine in triethylamine gave the benzodiazepine derivatives 3a–b.
Al-Jaber, Nabila A.   +2 more
openaire   +1 more source

Green Synthesis of 4-Nitro-4’-Methoxy Chalcone by Grinding Technique and its Antibacterial Activity

open access: yesJurnal Kimia Sains dan Aplikasi
This research aims to synthesize 4-nitro-4’-methoxy chalcone and determine the potential of 4-nitro-4’-methoxy chalcone as an antibacterial against Staphylococcus aureus and Escherichia coli bacteria.
Elfi Susanti V. H.   +5 more
doaj   +1 more source

STUDI PELEPASAN TERKONTROL TERHADAP NANOENKAPSULASI DIMETOKSI AMINO CALKON SEBAGAI DESAIN KANDIDAT SENYAWA ANTI KANKER YANG EFEKTIF

open access: yesJurnal Kimia Riset, 2016
ABSTRAK Enkapsulasi merupakan sebuah proses dimana partikel kecil dikemas dalam sebuah partikel yang lebih besar sehingga membentuk kapsul. Metode tersebut akan digunakan untuk memodifikasi calkon, senyawa anti kanker yang memiliki kelarutan dalam air ...
Mochamamad Zakki Fahmi   +3 more
doaj   +1 more source

chalcones [PDF]

open access: yes, 2014
Citation: 'chalcones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C00966 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals

open access: yesAdvanced Functional Materials, EarlyView.
The current work introduces a photoreversible polyester network derived from radical ring‐opening polymerization of cyclic ketene acetals. It combines photoreversible cross‐linking with initiator‐free multi‐photon printing. Reversible network formation, tunable mechanical properties, and selective degradation highlight its potential as a versatile ...
Till Meissner   +5 more
wiley   +1 more source

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