Results 41 to 50 of about 30,495 (265)
Machine Learning Accelerates Crystallization for Structure Determination
Angewandte Chemie, EarlyView.Single‐crystal X‐ray diffraction (SCXRD) is often constrained by the difficulty of obtaining suitable crystals. Here, a machine learning‐accelerated co‐crystal discovery workflow is established for a crystalline mate strategy that achieves over 95% prediction accuracy and experimentally delivers 114 co‐crystals from 120 candidates.
Cui‐Zhou Luan +10 more
wiley +2 more sources
Regulation of autophagy-related gene expressions by Trans-chalcone in the lungs of adult male rats [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریزBackground. Autophagy is responsible for maintaining cellular homeostasis by degrading and recycling macromolecules and unwanted intracellular components, such as damaged organelles.
Fatemeh Salehi Mazdeh +4 more
doaj +1 more source
Natural Product Rottlerin Derivatives Targeting Quorum Sensing
Molecules, 2021 Rottlerin is a natural product consisting of chalcone and flavonoid scaffolds, both of which have previously shown quorum sensing (QS) inhibition in various bacteria.
Dittu Suresh +6 more
doaj +1 more source
SYNTHESIS AND CYTOTOXIC ACTIVITY OF CHALCONE DERIVATIVES ON HUMAN BREAST CANCER CELL LINES
Indonesian Journal of Chemistry, 2012 Chalcone, an α,β-unsaturated ketone, has been shown have many biological activities such as anticancer and antifungi. This research was conducted to synthesize the chalcone derivatives and to obtain their cytotoxic activity on human cervix cancer cell ...
Nuraini Harmastuti +4 more
doaj +1 more source
Antibiotics, 2022 Naringenin and its glycosylated derivative naringin are flavonoids that are synthesized by the phenylpropanoid pathway in plants. We found that naringenin is also formed by the actinobacterium Streptomyces clavuligerus, a well-known microorganism used to
Juan F. Martín, Paloma Liras
doaj +1 more source
Jurnal Kimia Riset, 2016 ABSTRAK Enkapsulasi merupakan sebuah proses dimana partikel kecil dikemas dalam sebuah partikel yang lebih besar sehingga membentuk kapsul. Metode tersebut akan digunakan untuk memodifikasi calkon, senyawa anti kanker yang memiliki kelarutan dalam air ...
Mochamamad Zakki Fahmi +3 more
doaj +1 more source
, 2014 Citation: 'chalcones' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.C00966 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
In silico screening of chalcones against Epstein-Barr virus nuclear antigen 1 protein [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2020 The Epstein-Barr nuclear antigen 1 (EBNA1) is a crucial protein expressed by the Epstein-Barr virus (EBV). The EBNA1 is necessary for the replication and transcriptional regulation of latent gene expression of the EBV.
Nitchakan Darai +6 more
doaj +1 more source
Advanced Science, EarlyView.This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu +9 more
wiley +1 more source
BMC Genomics, 2019 Background Trichophyton rubrum is the main etiological agent of skin and nail infections worldwide. Because of its keratinolytic activity and anthropophilic nature, infection models based on the addition of protein substrates have been employed to assess
Tamires Aparecida Bitencourt +11 more
doaj +1 more source