Results 41 to 50 of about 48,655 (255)

SYNTHESIS AND CYTOTOXIC ACTIVITY OF CHALCONE DERIVATIVES ON HUMAN BREAST CANCER CELL LINES

open access: yesIndonesian Journal of Chemistry, 2012
Chalcone, an α,β-unsaturated ketone, has been shown have many biological activities such as anticancer and antifungi. This research was conducted to synthesize the chalcone derivatives and to obtain their cytotoxic activity on human cervix cancer cell ...
Nuraini Harmastuti   +4 more
doaj   +1 more source

In silico screening of chalcones against Epstein-Barr virus nuclear antigen 1 protein [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2020
The Epstein-Barr nuclear antigen 1 (EBNA1) is a crucial protein expressed by the Epstein-Barr virus (EBV). The EBNA1 is necessary for the replication and transcriptional regulation of latent gene expression of the EBV.
Nitchakan Darai   +6 more
doaj   +1 more source

Chiral Modification of the Tetrakis(pentafluorophenyl)borate Anion with Myrtanyl Groups [PDF]

open access: yes, 2019
The synthesis and characterization of chiral [B(C6F5)4]– derivatives bearing a myrtanyl group instead of a fluoro substituent in the para position are described.
Oestreich, Martin, Pommerening, Phillip
core   +1 more source

STUDI PELEPASAN TERKONTROL TERHADAP NANOENKAPSULASI DIMETOKSI AMINO CALKON SEBAGAI DESAIN KANDIDAT SENYAWA ANTI KANKER YANG EFEKTIF

open access: yesJurnal Kimia Riset, 2016
ABSTRAK Enkapsulasi merupakan sebuah proses dimana partikel kecil dikemas dalam sebuah partikel yang lebih besar sehingga membentuk kapsul. Metode tersebut akan digunakan untuk memodifikasi calkon, senyawa anti kanker yang memiliki kelarutan dalam air ...
Mochamamad Zakki Fahmi   +3 more
doaj   +1 more source

Silencing CHALCONE SYNTHASE in maize impedes the incorporation of tricin into lignin and increases lignin content [PDF]

open access: yes, 2016
Lignin is a phenolic heteropolymer that is deposited in secondary-thickened cell walls, where it provides mechanical strength. A recent structural characterization of cell walls from monocot species showed that the flavone tricin is part of the native ...
Boerjan, Wout   +12 more
core   +1 more source

Beyond antioxidants: the cellular and molecular interactions of flavonoids and how these underpin their actions on the brain [PDF]

open access: yes, 2010
The consumption of flavonoid-rich foods and beverages has been suggested to limit the neurodegeneration associated with a variety of neurological disorders and to prevent or reverse normal or abnormal deteriorations in cognitive performance.
Spencer, Jeremy Paul
core   +1 more source

Thermal study of chalcones [PDF]

open access: yesJournal of Thermal Analysis and Calorimetry, 2018
Chalcones α-β-unsaturated ketones are found in large plant species. Synthesis of chalcones and its three analogues hydroxy group at 2′, 3′ and 4′ positions (2–4) was carried out. The studies of thermal behavior were made by thermogravimetry (TG) and differential scanning calorimetry, both under oxygen and nitrogen purge gases.
Marcelo Kobelnik   +5 more
openaire   +2 more sources

Trans-chalcone activity against Trichophyton rubrum relies on an interplay between signaling pathways related to cell wall integrity and fatty acid metabolism

open access: yesBMC Genomics, 2019
Background Trichophyton rubrum is the main etiological agent of skin and nail infections worldwide. Because of its keratinolytic activity and anthropophilic nature, infection models based on the addition of protein substrates have been employed to assess
Tamires Aparecida Bitencourt   +11 more
doaj   +1 more source

Surface intermediate species of the 4-isobutylacetophenone adsorption-reaction over fosfotungstic Wells-Dawson heteropoly acid [PDF]

open access: yes, 2009
Surface adsorbed species of isobutylbenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid have been screened in the present investigation.
Briand, Laura Estefania   +2 more
core   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci   +13 more
wiley   +1 more source

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