Results 61 to 70 of about 30,495 (265)

Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: synthesis and biological evaluation of antivascular activity.

open access: yes, 2009
The alpha-methyl chalcone SD400 is a potent inhibitor of tubulin assembly and possesses potent anticancer activity. Various chalcone analogues were synthesized and evaluated for their cell growth inhibitory properties against the K562 human chronic ...
Kendall, A   +5 more
core   +1 more source

Trans-Chalcone Attenuates Pain and Inflammation in Experimental Acute Gout Arthritis in Mice

open access: yesFrontiers in Pharmacology, 2018
Gouty arthritis is characterized by an intense inflammatory response to monosodium urate crystals (MSU), which induces severe pain and reduction in the life quality of patients.
Larissa Staurengo-Ferrari   +12 more
doaj   +1 more source

Cytotoxic Activity of Methoxy-4’amino Chalcone Derivatives Against Leukemia Cell Lines

open access: yesMCBS (Molecular and Cellular Biomedical Sciences), 2019
Background: Chemotherapy is a common treatment for leukemia as well as in other cancer treatment. The lack of tumor selectivity and development of multi-drug resistance by chemotherapy caused the development of new strategy in cancer treatment become a ...
Arina Novilla   +4 more
doaj   +1 more source

A Photoswitchable Chalcone-Carbohydrate Conjugate Obtained by CuAAC Click Reaction [PDF]

open access: yes, 2022
Flavylium/Chalcone-based molecular switches comprise features such as pH-gated photochromism and fluorescence properties that make them attractive for many applications, ranging from stimuli-responsive materials to photopharmacology. However, in contrast
Pereira, Maria Manuela A.   +5 more
core   +1 more source

Evaluation of the anti-tumor and immunomodulatory effects of synthetic chalcones in a tumor mouse model [PDF]

open access: yesEgyptian Journal of Cancer and Biomedical Research, 2019
Introduction: Traditional treatment of cancer by using chemotherapy not only kills cancer cells but also normal cells. It also fails in the complete prevention of the spread of tumor cells. Chalcone have several biological activities, such as antioxidant,
Mohamed Nasef   +3 more
doaj   +1 more source

Effects of high‐moisture extrusion processing on reducing anti‐nutritional factors and allergenicity in plant‐based materials—A mini review

open access: yesFood Biomacromolecules, EarlyView.
Abstract The rising demand for plant‐based meat alternatives has had advancements in processing technologies such as extrusion to meet consumer preferences for enhanced sensory qualities and nutritional benefits. High moisture extrusion (HME), a thermo‐mechanical process employing elevated moisture levels (40%–70%), has emerged as a promising method ...
Nur Hameedah Binte Ramadhan   +2 more
wiley   +1 more source

Green Synthesis of Chalcone Derivatives Using Chalcones as Precursor

open access: yes, 2022
Recently, the use of green methodologies like sonication, use of ionic liquids, etc. attracted the attention of researchers in the field of organic synthesis as they have advantages such as mild reaction conditions, environmentally benign procedures, etc.
Surbhi Dhadda   +2 more
openaire   +1 more source

Development and validation of a UV–Vis spectrophotometric method for estimation of total content of chalcone

open access: yesMethodsX
In this study, a straightforward spectrophotometric method was developed for quantifying the total content of chalcones in a sample. The method exhibits linearity, accuracy, precision, repeatability, and enables the estimation of total chalcone content ...
J.R.S. Botelho   +4 more
doaj   +1 more source

Advances in protein–polyphenol complexation: Unraveling mechanisms, modulation, and functional outcomes

open access: yesFood Biomacromolecules, EarlyView.
Abstract Polyphenolic compounds have attracted increasing market demand and extensive attention due to their potential health benefits and bioactivities. Meanwhile, proteins are widely used in the food industry for their nutritional and functional properties. However, the application of proteins in the food industry is often limited by challenges, such
Fang Li   +7 more
wiley   +1 more source

Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects

open access: yesFuture Postharvest and Food, Volume 3, Issue 2, Page 142-162, June 2026.
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq   +2 more
wiley   +1 more source

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