Results 71 to 80 of about 28,625 (273)

Synthesis and Identification of Phenyl Azochalcone & bis- azo – Chalcone Derivatives Derived from P-amino Acetophenone [PDF]

open access: yesKirkuk Journal of Science, 2018
This work involves the synthesis of different substituted amino-chalcones via claisen- schmidt condensation reaction between p-amino acetophenone and different aromatic substituted benzaldehydes. The second step involves the conversion of amino-chalcones
Zahraa Talib Ghlib   +2 more
doaj   +1 more source

Chalcone suppresses tumor growth through NOX4-IRE1α sulfonation-RIDD-miR-23b axis

open access: yesRedox Biology, 2021
Chalcone is a polyphenolic compound found abundantly in natural plant components. They have been acclaimed as potential antitumor compounds in multiple tumor cells. However, not much attention has been paid to elucidate its antitumor mechanism of action.
Hyun-Kyoung Kim   +8 more
doaj  

Tandem chalcone-sulfonamide hybridization, cyclization and further Claisen–Schmidt condensation: Tuning molecular diversity through reaction time and order and catalyst

open access: yesArabian Journal of Chemistry, 2020
We here report the synthesis of novel chalcone-sulfonamide compounds based on the hybridization at 2′ position and nitro substitution at the side chalcone phenyl ring followed by tandem cyclization into quinolinone derivatives and then a further aldol ...
Mirian R.C. de Castro   +7 more
doaj  

Evaluation of direct pulp capping with a synthetic chalcone: a preliminary histological study.

open access: yesJournal of Oral Research, 2015
The aim of this study is to evaluate the action of the synthetic chalcone 1-phenyl-3-(4-chlorophenyl)-2-propen-1-one to induce pulp healing in rats.
David Tames   +6 more
doaj   +1 more source

Chalcone Attenuates Staphylococcus aureus Virulence by Targeting Sortase A and Alpha-Hemolysin

open access: yesFrontiers in Microbiology, 2017
Staphylococcus aureus (S.aureus) resistance, considered a dilemma for the clinical treatment of this bacterial infection, is becoming increasingly intractable.
Bing Zhang   +9 more
doaj   +1 more source

Exploring quinolinone–chalcones: Synthesis, antioxidant potential and industrial applications in biofuels

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biofuels undergo oxidative degradation, which reduces their storage stability and efficiency, hindering their large‐scale adoption and integration into the global energy matrix. To address this issue, we synthesized and characterized four novel quinolinone–chalcone derivatives (substituted with Br, Cl, OCH3 and OCH2CH3) as potential ...
Vitor S. Duarte   +8 more
wiley   +1 more source

One‐Pot Hetero‐Di‐C‐Glycosylation of the Natural Polyphenol Phloretin by a Single C‐Glycosyltransferase With Broad Sugar Substrate Specificity

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 5, Page 1296-1304, May 2025.
Here, an efficient system for synthesizing high‐value polyphenol hetero‐di‐C‐glycosides with two distinct C‐glycosyl residues was established using a two‐step glycosylation catalyzed by C‐glycosyltransferase in one pot. The desired C‐β‐galactosyl‐C‐β‐glucosyl and C‐β‐glucosyl‐C‐β‐xylosyl phloretin were obtained at concentrations of 0.6 and 6 g/L ...
Tuo Li   +4 more
wiley   +1 more source

Biocatalytic access to diverse prenylflavonoids by combining a regiospecific C-prenyltransferase and a stereospecific chalcone isomerase

open access: yesActa Pharmaceutica Sinica B, 2018
Prenylflavonoids are valuable natural products that have diverse biological properties, and are usually generated biologically by multiple metabolic enzymes in nature.
Jianhua Li   +6 more
doaj  

Structural and Interactional Analysis of the Flavonoid Pathway Proteins: Chalcone Synthase, Chalcone Isomerase and Chalcone Isomerase-like Protein

open access: yesInternational Journal of Molecular Sciences
Chalcone synthase (CHS) and chalcone isomerase (CHI) catalyze the first two committed steps of the flavonoid pathway that plays a pivotal role in the growth and reproduction of land plants, including UV protection, pigmentation, symbiotic nitrogen fixation, and pathogen resistance.
Jacob A. Lewis   +7 more
openaire   +2 more sources

Nanomaterials for co‐immobilization of multiple enzymes

open access: yesBMEMat, Volume 3, Issue 1, March 2025.
This review offers an overview of commonly used methods and strategies for enzyme co‐immobilization and summarizes recent research advancements in nanomaterials for enzyme co‐immobilization over the past 5 years. Also, the advantages and challenges of these nanomaterials for enzyme co‐immobilization are also discussed along with potential future ...
Jingyu Zhang   +3 more
wiley   +1 more source

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