A SQUAMOSA MADS-box gene involved in the regulation of anthocyanin accumulation in bilberry fruits [PDF]
Anthocyanins are important health promoting phytochemicals that are abundant in many fleshy fruits. Bilberry (Vaccinium myrtillus L.) is one of the best sources of these compounds.
Fraser, Paul D.+11 more
core +5 more sources
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles [PDF]
New N-acetyl/N-thiocarbamoylpyrazoline derivatives were designed and synthesized in high yields to assess their inhibitory activity and selectivity against human monoamine oxidase A and B.
Carradori, Simone+8 more
core +1 more source
Chalcones IX : Syntheses of Some Methoxy Chalcones
Department of Chemistry, H. B. Technological Institute, Kanpur Received 15 October 1971 Chalcones IX : Syntheses of Some Methoxy Chalcones.
SHYAM SUNDER MISRA, DINKAR
openaire +3 more sources
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype [PDF]
Hedgehog (Hh) inhibitors have emerged as valid tools in the treatment of a wide range of cancers. Indeed, aberrant activation of the Hh pathway occurring either by ligand-dependent or -independent mechanisms is a key driver in tumorigenesis.
Alfonsi, Romina+13 more
core +1 more source
Control of anthocyanin biosynthesis pathway gene expression by eutypine, a toxin from Eutypa lata, in grape cell tissue cultures [PDF]
Eutypine, 4-hydroxy-3-(3-methyl-3-butene-1-ynyl) benzaldehyde, is a toxin produced by Eutypa lata, the causal agent of Eutypa dieback in grapevine. The effect of the toxin on anthocyanin synthesis has been investigated in Vitis vinifera cv.
Afifi, Maha+6 more
core +2 more sources
The effects of trans-chalcone and chalcone 4 hydrate on the growth of Babesia and Theileria
Chemotherapy is a principle tool for the control and prevention of piroplasmosis. The search for a new chemotherapy against Babesia and Theileria parasites has become increasingly urgent due to the toxic side effects of and developed resistance to the current drugs.
Naoaki Yokoyama+8 more
openaire +5 more sources
The chemical modification and optimization of biologically active compounds are essential steps in the identification of promising lead compounds for drug development.
Byung-Hak Kim+3 more
doaj +1 more source
How to perform RT-qPCR accurately in plant species?: a case study on flower colour gene expression in an azalea (Rhododendron simsii hybrids) mapping population [PDF]
Background: Flower colour variation is one of the most crucial selection criteria in the breeding of a flowering pot plant, as is also the case for azalea (Rhododendron simsii hybrids).
De Keyser, Ellen+3 more
core +2 more sources
Our previous work identified isoxazole-based chalcones and their dihydropyrazole derivatives as two important five-membered heterocycles having antitubercular activity.
A. Shaik+5 more
semanticscholar +1 more source
Trans-Chalcone Attenuates Pain and Inflammation in Experimental Acute Gout Arthritis in Mice
Gouty arthritis is characterized by an intense inflammatory response to monosodium urate crystals (MSU), which induces severe pain and reduction in the life quality of patients.
Larissa Staurengo-Ferrari+12 more
doaj +1 more source