Results 71 to 80 of about 22,058 (147)

Direct synthesis, characterization, in vitro and in silico studies of simple chalcones as potential antimicrobial and antileishmanial agents

Royal Society Open Science
Chalcone represents a vital biosynthetic scaffold owing to its numerous therapeutic effects. The present study was intended to synthesize 17 chalcone derivatives (3a–q) by direct coupling of substituted acetophenones and benzaldehyde.
Haroon ur Rashid, Sherwali Khan, Irum, Asad Khan, Nasir Ahmad, Tanzeel Shah, Khalid Khan   +6 more
doaj   +1 more source

Comprehensive investigation on two-photon absorption enhancement via excited-state charge transfer in terminal modified chalcone derivatives

Results in Chemistry
Three chalcone derivatives with different terminal modifications (furan, biphenyl, pyrenyl) were designed and synthesized. The nonlinear optical (NLO) properties of chalcone derivatives were comprehensively analyzed by Z-scan, transient absorption ...
Linpo Yang, Jia Wei, Xueru Zhang, Yuxiao Wang, Minggen Zhao, Yinglin Song   +5 more
doaj   +1 more source

Pharmaceutical Potential of 2’,4’-Dichloro-4-Hydroxy-3-Methoxychalcone Synthesized from Vaniline

Journal of Tropical Pharmacy and Chemistry, 2018
Chalcone is an intermediate compound as the main precursor for the biosynthesis of flavonoid in plants. Chalcone has been known to have variety of different pharmacological activities.
Eka Rizky Meilinda, Hajrah Hajrah, Agung Rahmadani, Laode Rijai   +3 more
doaj  

Structural, electronic and bioactive profiling of a 2'-hydroxychalcone-Ag composite: a DFT-supported biomedical study on anticancer, antioxidant and antibacterial activities. [PDF]

RSC Adv
Butt AL, Saira F, Ahmed S, Tahir S, Iqbal A, Siddiqa A, Mazhar K, Sohaila Naz S.   +7 more
europepmc   +1 more source

Design, Synthesis, and Evaluation of Bis-Chalcones and Bis-Flavones as Selective COX-2 Inhibitors. [PDF]

Chem Biol Drug Des
Pereira R, Freitas M, Araújo AN, Silva VLM, Fernandes E.   +4 more
europepmc   +1 more source

Transition-Metal-Free One-Pot Synthesis of (Hetero)chalcones with Cysteine Protease Inhibitory Activity. [PDF]

ACS Omega
Arroio TR, Caires FJ, Almeida GO, Fernandes VHC, Pinto IWF, de Oliveira LVS, Vieira PC, Clososki GC.   +7 more
europepmc   +1 more source

Design, synthesis, and biological evaluation of novel chalcone derivatives: integrating molecular docking with <i>in vivo</i> anti-inflammatory and antinociceptive studies. [PDF]

RSC Adv
Shamim A, Nadeem H, Masaud SM, Hussain T, Bashir K, Alrokayan S, Haq IU, Latif M, Imran M, Irshad N.   +9 more
europepmc   +1 more source

Triazole and Pyrazole Hybrids of Electrophilic Natural Products as Promising Anticancer Agents. [PDF]

Molecules
Fermo AD, Bisi A, Orioli R, Gobbi S, Belluti F.   +4 more
europepmc   +1 more source

Mechanistic insights into hydroxy(tosyloxy)iodobenzene-mediated ditosyloxylation of chalcones: a DFT study. [PDF]

Beilstein J Org Chem
Parkash J, Saini S, Saini V, Bains O, Kamal R.   +4 more
europepmc   +1 more source

Theoretical Study of Electrostatic Embedding and Properties of a Novel Quinolinone-Chalcone Crystal and a Comparative Analysis with Dihydroquinolinone Analogs. [PDF]

ChemistryOpen
Valverde C, Pires NM, Borges AN, Fernandes DC, Duarte VS, D'Oliveira GDC, Custodio JMF, Pérez CN, Osório FAP, Napolitano HB.   +9 more
europepmc   +1 more source