A conserved strategy of chalcone isomerase-like protein to rectify promiscuous chalcone synthase specificity [PDF]
Nature Communications, 2020 Chalcone synthase is the first committed enzyme in the plant flavonoid biosynthesis pathway, yet shows low product specificity in vitro. Here Waki et al.
Toshiyuki Waki +20 more
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Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase. [PDF]
J Nat Prod, 2023 By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation–thiolation didomain, which catalyzes the formation of naringenin chalcone, was found.
Furumura S +7 more
europepmc +4 more sources
Lineage-Specific Expansion of the Chalcone Synthase Gene Family in Rosids. [PDF]
PLoS ONE, 2015 Rosids are a monophyletic group that includes approximately 70,000 species in 140 families, and they are found in a variety of habitats and life forms. Many important crops such as fruit trees and legumes are rosids.
Kattina Zavala, Juan C Opazo
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Identification of annotation artifacts concerning the chalcone synthase (CHS) [PDF]
BMC Research Notes, 2023 Objective Chalcone synthase (CHS) catalyzes the initial step of the flavonoid biosynthesis. The CHS encoding gene is well studied in numerous plant species.
Martin Bartas +3 more
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Genome-wide identification and localization of chalcone synthase family in soybean (Glycine max [L]Merr). [PDF]
BMC Plant Biol, 2018 Soybean is a paleopolyploid that has undergone two whole genome duplication events. Gene duplication is a type of genomic change that can lead to novel functions of pre-existing genes.
Anguraj Vadivel AK +3 more
europepmc +4 more sources
Genome-wide characterization of chalcone synthase genes in sweet cherry and functional characterization of CpCHS1 under drought stress. [PDF]
Front Plant Sci, 2022 Cherries are one of the important fruit trees. The growth of cherry is greatly affected by abiotic stresses such as drought, which hinders its development.
Hou Q +6 more
europepmc +2 more sources
Transcriptomic and Coexpression Network Analyses Revealed Pine Chalcone Synthase Genes Associated with Pine Wood Nematode Infection. [PDF]
Int J Mol Sci, 2021 Pine wood nematode (PWN) causes serious diseases in conifers, especially pine species. To investigate the transcriptomic profiles of genes involved in pine-PWN interactions, two different pine species, namely, Pinus thunbergii and P.
Chen Q, Zhang R, Li D, Wang F.
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E183K Mutation in Chalcone Synthase C2 Causes Protein Aggregation and Maize Colorless [PDF]
Frontiers in Plant Science, 2021 Flavonoids give plants their rich colors and play roles in a number of physiological processes. In this study, we identified a novel colorless maize mutant showing reduced pigmentation throughout the whole life cycle by EMS mutagenesis. E183K mutation in
Haixiao Dong +10 more
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Two Chalcone Synthase Isozymes Participate Redundantly in UV-Induced Sakuranetin Synthesis in Rice. [PDF]
Int J Mol Sci, 2020 Chalcone synthase (CHS) is a key enzyme in the flavonoid pathway, participating in the production of phenolic phytoalexins. The rice genome contains 31 CHS family genes (OsCHSs).
Park HL +5 more
europepmc +2 more sources
Discovery of a previously unknown biosynthetic capacity of naringenin chalcone synthase by heterologous expression of a tomato gene cluster in yeast. [PDF]
Sci Adv, 2020 A previously unknown chalcone synthase activity for HCAA synthesis is uncovered via characterization of a tomato gene cluster in yeast. Chalcone synthase (CHS) canonically catalyzes carbon-carbon bond formation through iterative decarboxylative Claisen ...
Kong D, Li S, Smolke CD.
europepmc +2 more sources