Results 211 to 220 of about 15,473 (263)

Design and Development of Sulfonamide-Chalcones as Antiepileptic Candidates: Computational and Zebrafish-Based Validation Approaches. [PDF]

ACS Omega
Adzahar AN, Nik Aizan NNF, Mohammad Latif MA, Mohd Fahmi MSA, Ismail AZ, Mohd Faudzi SM.   +5 more
europepmc   +1 more source

Quantifying Breslow intermediate reactivity in intermolecular Stetter reactions. [PDF]

Chem Sci
Duan Z, Zhu J, Majhi PK, Goodfellow AS, O'Donoghue AC, Young CM, Smith AD.   +6 more
europepmc   +1 more source

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Bioactivities of Chalcones

Current Medicinal Chemistry, 1999
This review outlines the different bioactivities of a variety of chalcones. The cytotoxic, anticancer, chemopreventative and mutagenic properties of a number of chalcones are described followed by an account of various of these unsaturated ketones as antimicrobial agents.
J R, Dimmock, D W, Elias, M A, Beazely, N M, Kandepu   +3 more
exaly   +3 more sources

Stereoselectivity of chalcone isomerase with chalcone derivatives: a computational study

Journal of Molecular Modeling, 2013
Chalcone isomerase (CHI) catalyzes the intramolecular cyclization of chalcones into flavonoids. The activity of CHI is essential for the biosynthesis of flavonoids precursors of floral pigments and phenylpropanoid plant defense compounds. In the present study, we explored the detailed binding structures and binding free energies for two different ...
Yuan, Yao, Hui, Zhang, Ze-Sheng, Li
openaire   +2 more sources

Anticancer activities of novel chalcone and bis-chalcone derivatives

Bioorganic & Medicinal Chemistry, 2006
A series of novel chalcones and bis-chalcones containing boronic acid moieties has been synthesized and evaluated for antitumor activity against the human breast cancer MDA-MB-231 (estrogen receptor-negative) and MCF7 (estrogen receptor-positive) cell lines and against two normal breast epithelial cell lines, MCF-10A and MCF-12A.
Aneta, Modzelewska, Catherine, Pettit, Geetha, Achanta, Nancy E, Davidson, Peng, Huang, Saeed R, Khan   +5 more
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An Amine-Promoted Aziridination of Chalcones

Angewandte Chemie - International Edition, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Yu-Mei Shen, Mei-Xin Zhao, Jiaxi Xu
exaly   +3 more sources

Chalcone dihalides—VII

Tetrahedron, 1975
Abstract 2′-hydroxychalcone dibromides substituted by OMe in the 6′-position are found to yield little or no aurone in dilute aqueous ethanolic potassium hydroxide. The proportion of aurone to flavone in their products parallels increasing hydroxide concentration.
J.A. Donnelly, H.J. Doran
openaire   +1 more source

Chemical sensing of chalcones by voltammetry: trans-Chalcone, cardamonin and xanthohumol

Electrochimica Acta, 2013
Abstract Xanthohumol (XN) and cardamonin (CD) belong to the chemical class of chalcones which are phenolic compounds of large interest due to their health promoting properties. In the present work, their electrochemical behavior on a hanging mercury drop electrode (HMDE) is compared to trans -chalcone by means of cyclic voltammetry (CV).
Tavares, E.M., Carvalho, A.M., Gonçalves, Luis M., Valente, I.M., Moreira, M.M., Guido, L.F., Rodrigues, J.A., Doneux, Thomas, Barros, Aquiles   +8 more
openaire   +2 more sources