Mechanistic insights into hydroxy(tosyloxy)iodobenzene-mediated ditosyloxylation of chalcones: a DFT study. [PDF]
Beilstein J Org ChemParkash J +4 more
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Chalcone and <i>Trans</i>-Chalcone Induce Transcriptomic Changes in <i>Caenorhabditis elegans</i> Compatible with a Novel Cumulative Damage Mode of Action. [PDF]
MoleculesGalli G +5 more
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Cyclization-Modulated Structure and Oxidative Behavior of Methoxy-Substituted Chalcones: Implications for Diesel-Biodiesel Additive Design. [PDF]
ACS Omegade Paula RLG +9 more
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This review outlines the different bioactivities of a variety of chalcones. The cytotoxic, anticancer, chemopreventative and mutagenic properties of a number of chalcones are described followed by an account of various of these unsaturated ketones as antimicrobial agents.
J R, Dimmock +3 more
exaly +3 more sources
Stereoselectivity of chalcone isomerase with chalcone derivatives: a computational study
Journal of Molecular Modeling, 2013Chalcone isomerase (CHI) catalyzes the intramolecular cyclization of chalcones into flavonoids. The activity of CHI is essential for the biosynthesis of flavonoids precursors of floral pigments and phenylpropanoid plant defense compounds. In the present study, we explored the detailed binding structures and binding free energies for two different ...
Yuan, Yao, Hui, Zhang, Ze-Sheng, Li
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Anticancer activities of novel chalcone and bis-chalcone derivatives
Bioorganic & Medicinal Chemistry, 2006A series of novel chalcones and bis-chalcones containing boronic acid moieties has been synthesized and evaluated for antitumor activity against the human breast cancer MDA-MB-231 (estrogen receptor-negative) and MCF7 (estrogen receptor-positive) cell lines and against two normal breast epithelial cell lines, MCF-10A and MCF-12A.
Aneta, Modzelewska +5 more
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Abstract 2′-hydroxychalcone dibromides substituted by OMe in the 6′-position are found to yield little or no aurone in dilute aqueous ethanolic potassium hydroxide. The proportion of aurone to flavone in their products parallels increasing hydroxide concentration.
J.A. Donnelly, H.J. Doran
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An Amine-Promoted Aziridination of Chalcones†
Angewandte Chemie - International Edition, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Jiaxi Xu, Yu-Mei Shen, Mei-Xin Zhao
exaly +3 more sources
Chemical sensing of chalcones by voltammetry: trans-Chalcone, cardamonin and xanthohumol
Electrochimica Acta, 2013Abstract Xanthohumol (XN) and cardamonin (CD) belong to the chemical class of chalcones which are phenolic compounds of large interest due to their health promoting properties. In the present work, their electrochemical behavior on a hanging mercury drop electrode (HMDE) is compared to trans -chalcone by means of cyclic voltammetry (CV).
Tavares, E.M. +8 more
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Expression of chalcone synthase and chalcone isomerase proteins in Arabidopsis seedlings
Plant Molecular Biology, 1997Antibodies have been developed against the first two enzymes of flavonoid biosynthesis in Arabidopsis thaliana. Chalcone synthase (CHS) and chalcone isomerase (CHI) were overexpressed and purified from Escherichia coli as fusion proteins with glutathione S-transferase from Schistosoma japonicum.
C C, Cain +3 more
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