Results 171 to 180 of about 10,638 (220)
Some of the next articles are maybe not open access.
Stereoselectivity of chalcone isomerase with chalcone derivatives: a computational study
Journal of Molecular Modeling, 2013Chalcone isomerase (CHI) catalyzes the intramolecular cyclization of chalcones into flavonoids. The activity of CHI is essential for the biosynthesis of flavonoids precursors of floral pigments and phenylpropanoid plant defense compounds. In the present study, we explored the detailed binding structures and binding free energies for two different ...
Yuan, Yao, Hui, Zhang, Ze-Sheng, Li
openaire +2 more sources
Anticancer activities of novel chalcone and bis-chalcone derivatives
Bioorganic & Medicinal Chemistry, 2006A series of novel chalcones and bis-chalcones containing boronic acid moieties has been synthesized and evaluated for antitumor activity against the human breast cancer MDA-MB-231 (estrogen receptor-negative) and MCF7 (estrogen receptor-positive) cell lines and against two normal breast epithelial cell lines, MCF-10A and MCF-12A.
Aneta, Modzelewska +5 more
openaire +2 more sources
Tetrahedron, 1975
Abstract 2′-hydroxychalcone dibromides substituted by OMe in the 6′-position are found to yield little or no aurone in dilute aqueous ethanolic potassium hydroxide. The proportion of aurone to flavone in their products parallels increasing hydroxide concentration.
J.A. Donnelly, H.J. Doran
openaire +1 more source
Abstract 2′-hydroxychalcone dibromides substituted by OMe in the 6′-position are found to yield little or no aurone in dilute aqueous ethanolic potassium hydroxide. The proportion of aurone to flavone in their products parallels increasing hydroxide concentration.
J.A. Donnelly, H.J. Doran
openaire +1 more source
Chemical sensing of chalcones by voltammetry: trans-Chalcone, cardamonin and xanthohumol
Electrochimica Acta, 2013Abstract Xanthohumol (XN) and cardamonin (CD) belong to the chemical class of chalcones which are phenolic compounds of large interest due to their health promoting properties. In the present work, their electrochemical behavior on a hanging mercury drop electrode (HMDE) is compared to trans -chalcone by means of cyclic voltammetry (CV).
Tavares, E.M. +8 more
openaire +2 more sources
Expression of chalcone synthase and chalcone isomerase proteins in Arabidopsis seedlings
Plant Molecular Biology, 1997Antibodies have been developed against the first two enzymes of flavonoid biosynthesis in Arabidopsis thaliana. Chalcone synthase (CHS) and chalcone isomerase (CHI) were overexpressed and purified from Escherichia coli as fusion proteins with glutathione S-transferase from Schistosoma japonicum.
C C, Cain +3 more
openaire +2 more sources
Acta Crystallographica Section C Crystal Structure Communications, 1993
1-(7-Hydroxy-2,2-dimethylchroman-6-yl)-3-phenyl-2-propen-1-one, C 20 H 20 O 3 , M r =308.38, P2 1 /a, a=12.002 (2), b=11.013 (2), c=12.652 (3) A, β=106.24 (3) o , V=1605.6 A 3 , Z=4, D m =1.26 (2), D x =1.275 Mg m -3 , λ(Mo Kα)=0.71069 A, μ=0.079 mm -1 , F(000)=656, T=293 K, R=0.037, wR=0.034 for 892 reflections with I>3σ(I).
ALEX, G +5 more
openaire +2 more sources
1-(7-Hydroxy-2,2-dimethylchroman-6-yl)-3-phenyl-2-propen-1-one, C 20 H 20 O 3 , M r =308.38, P2 1 /a, a=12.002 (2), b=11.013 (2), c=12.652 (3) A, β=106.24 (3) o , V=1605.6 A 3 , Z=4, D m =1.26 (2), D x =1.275 Mg m -3 , λ(Mo Kα)=0.71069 A, μ=0.079 mm -1 , F(000)=656, T=293 K, R=0.037, wR=0.034 for 892 reflections with I>3σ(I).
ALEX, G +5 more
openaire +2 more sources
STEM CELLS, 1994
On the basis of our recent findings that licochalcone A isolated from Xin-jiang licorice showed anti-inflammatory and anti-tumorigenic activities, we synthesized more than 40 chalcone derivatives to examine their anti-tumorigenic activities. In vitro inhibitory activity against phosphorylation of phospholipids promoted by tetradecanoylphorbol-13 ...
openaire +2 more sources
On the basis of our recent findings that licochalcone A isolated from Xin-jiang licorice showed anti-inflammatory and anti-tumorigenic activities, we synthesized more than 40 chalcone derivatives to examine their anti-tumorigenic activities. In vitro inhibitory activity against phosphorylation of phospholipids promoted by tetradecanoylphorbol-13 ...
openaire +2 more sources
Antimalarial Activity of Ferrocenyl Chalcones.
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Wu, X., Wilairat, P., Go, M.-L.
openaire +2 more sources
Coupling–Isomerization Synthesis of Chalcones
Chemistry – A European Journal, 2006AbstractThe Sonogashira coupling of electron‐deficient (hetero)aryl halides 1 and (hetero)aryl or alkenyl 1‐propargyl alcohols 2 does not terminate at the stage of the expected internal propargyl alcohols, but rather gives rise to the formation of α,β‐unsaturated ketones 3 with a variety of acceptor substituents.
Roland U, Braun +2 more
openaire +2 more sources