Results 161 to 170 of about 15,473 (263)

Structure-guided hydrophobic modulation at the 3-position of <i>Senecio nutans</i>-derived chalcones Drives divergent vascular mechanisms. [PDF]

Front Pharmacol
Palacios J, Yu González CL, Aravena D, Romero-Parra J, Martínez-Cifuentes M, Parra C.   +5 more
europepmc   +1 more source

A Near Telomere‐to‐Telomere Genome of Belamcanda chinensis Provides Insights Into Genome Evolution and the Biosynthesis of Characteristic Isoflavones

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4285-4301, June 2026.
ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Yuan‐Yuan Wang, Bi‐Huan Chen, Gui‐Sheng Xiang, Yi‐Na Wang, Run Yang, Xiao‐Bo Li, Shi‐Yan Yuan, Yu‐Cheng Zhao, Guang‐Hui Zhang, Min‐Jian Qin, Sheng‐Chao Yang   +10 more
wiley   +1 more source

Licorice-derived prenylated chalcones alleviate knee osteoarthritis via multi-target modulation of PI3K-Akt, MAPK and HIF-1α signaling: an integrative UPLC-Q-TOF-MS/MS, network pharmacology and molecular dynamics study. [PDF]

Front Bioinform
Qian W, Zeng J.
europepmc   +1 more source

The ZmCOP1s–ZmCOL3 Module Enhances Late Flowering, Grain Yield and Grain Quality in Maize

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4415-4432, June 2026.
ABSTRACT Flowering time is a key determinant of yield and regional adaptation in crops and is largely controlled by light signalling. In this study, we identified two maize orthologs of Arabidopsis CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1), designated ZmCOP1a and ZmCOP1b, which activate light signalling and reduce plant height. Loss‐of‐function mutants of
Shuling Yang, Yanpei Zhang, Lianhua Cui, Weimin Zhan, Shizhan Chen, Yu Zhang, Haolei Han, Linhu Song, Longchao Du, Kangni Zhang, Huan Liu, Shaoci Wang, Yong Shi, Jihua Tang, Xiangguo Liu, Jianping Yang   +15 more
wiley   +1 more source

Discovery of Synthetic Imine-Chalcones Targeting Mayaro Virus Replication. [PDF]

Pathogens
Corrêa-Amorim LDS, Rocha NCD, Barboza GKP, Carlos MFLP, Echevarria A, Rabelo VW, Paixão ICNP.   +6 more
europepmc   +1 more source

Genome assembly and genome‐wide association studies decipher the genetic basis of isovitexin synthesis and yield traits in mungbean

The Plant Journal, Volume 126, Issue 5, June 2026.
Significance Statement A high‐quality mungbean genome was assembled and connected with domestication and GWAS analysis. EVM0030058 improved isovitexin in hairy roots. VrLFRH1 was found associated with yield‐related traits. This study presents a high‐quality chromosome‐level genome assembly of the southern Chinese mungbean cultivar Sulv1, with superior ...
Jinyang Liu, Suhua Zhang, Qiang Yan, Jingbin Chen, Yun Lin, Chenchen Xue, Ranran Wu, Prakit Somta, Xingxing Yuan, Yuan‐Ming Zhang, Xin Chen   +10 more
wiley   +1 more source

Synthesis and Bioactivity Studies of Benzimidazole-Chalcone Hybrids. [PDF]

Molecules
Makgoathana HD, Mthembu ST, Mhlanga TV, Selepe MA, Sonopo MS.   +4 more
europepmc   +1 more source

Overexpression of cytosolic NADP‐malic enzyme 1 from the common ice plant enhances water‐deficit and high‐light stress tolerance by modulating water‐use efficiency and flavonoid biosynthesis

The Plant Journal, Volume 126, Issue 5, June 2026.
SUMMARY Innovative strategies are essential to enhance crop resilience against drought and heat stress intensified by climate change. Crassulacean acid metabolism (CAM) is a specialized photosynthetic pathway that improves water‐use efficiency (WUE) by shifting CO2 fixation to the nighttime. The common ice plant (Mesembryanthemum crystallinum) utilizes
Sang Hun Kim, Dong Yeol Song, Chan Hui Lee, Seo Young Yang, John C. Cushman, Sung Don Lim   +5 more
wiley   +1 more source

Natural chalcones as dual inhibitors of HDACs and NF-κB

, 2012
Histone deacetylase enzymes (HDACs) are emerging as a promising biological target for cancer and inflammation. Using a fluorescence assay, we tested the in vitro HDAC inhibitory activity of twenty-one natural chalcones, a widespread group of natural ...
Orlikova, B., Diederich, M., Golais, F., Schnekenburger, M., Zloh, Mire, Tasdemir, D.   +5 more
core  

Cytotoxic Profiling of 3',4',5'-Trimethoxychalcones Reveals Cell-Line-Dependent Cytotoxic Activity: An In Vitro and In Silico Study. [PDF]

Chem Biodivers
Mehandzhiyski AY, Beraich A, Velkov Z, Zaharieva M, Konstantinov S, Batovska D.   +5 more
europepmc   +1 more source